Inhibition of the RTEM .beta.-lactamase from Escherichia coli. Interaction of the enzyme with derivatives of olivanic acid

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

1978 • 791 citations

Penicillinase Synthesis Controlled By Infectious R Factors In Enterobacteriaceae

1965 • 555 citations

The β-lactamases of Gram-negative bacteria and their rôle in resistance to β-lactam antibiotics

1976 • 539 citations

Thienamycin, a new .BETA.-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties.

1979 • 502 citations

Naturally-occurring .BETA.-lactamase inhibitors with antibacterial activity.

1976 • 388 citations

.beta.-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin

1980 • 222 citations

Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

1978 • 204 citations

Analytical isoelectric focusing of R factor-determined beta-lactamases: correlation with plasmid compatibility

1976 • 172 citations

THE α-KETO ANALOGUES OF ARGININE, ORNITHINE, AND LYSINE

1954 • 152 citations

A direct spectrophotometric assay and determination of Michaelis constants for the β-lactamase reaction

1975 • 144 citations

Mechanisms of action of naturally occurring irreversible enzyme inhibitors

1975 • 144 citations

Penicillinase active sites: Labelling of serine‐44 in β‐lactamase I by 6β‐bromopenicillanic acid

1979 • 129 citations

6-beta-bromopenicillanic acid, a potent beta-lactamase inhibitor.

1978 • 105 citations

A semi-synthetic penicillinase inactivator

1979 • 91 citations

Structures of olivanic acid derivatives MM 4550 and MM 13902; two new, fused β-lactams isolated from Streptomyces olivaceus

1977 • 88 citations

Acquisition of substrate-specific parameters during the catalytic reaction of penicillinase.

1976 • 85 citations

β-Lactamase inactivation by mechanism-based reagents

1980 • 79 citations

6 β-Bromopenicillanic acid inactivates β-lactamase I

1979 • 75 citations

Isolation and structure of a .BETA.-lactamase inhibitor from Streptomyces.

1977 • 56 citations

PS-5 inhibition of a .BETA.-lactamase from Proteus vulgaris.

1980 • 23 citations

Inhibition of β-lactamase of Bacillus licheniformis 749/C by compound PS-5, a new β-lactam antibiotic

1980 • 22 citations

Theoretical considerations on the indirect determination of anionsDetermination of sulphate with barium chloranilate

1964 • 19 citations

Biphasic kinetics induced by modified substrates of penicillinase

1975 • 11 citations

Méthode Modifiée pour la Préparation des Acides α‐Sulfoncarboxyliques

1920 • 7 citations