Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

Spot Tests in Organic Analysis

1966 • 1,836 citations

Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus

1977 • 695 citations

[38] Gel electrofocusing

1971 • 307 citations

Micro-iodometric assay for penicillinase

1962 • 292 citations

Clavulanic acid, a novel β-lactam isolated from Streptomyces clavuligerus; X-ray crystal structure analysis

1976 • 160 citations

A direct spectrophotometric assay and determination of Michaelis constants for the β-lactamase reaction

1975 • 144 citations

Imidazole Catalysis

1959 • 142 citations

Conjugal transfer of R plasmids in Neisseria gonorrhoeae

1977 • 111 citations

Conjugal Transfer of the Gonococcal Penicillinase Plasmid

1977 • 100 citations

Nocardicin A and B, monocyclic .beta.-lactam antibiotics from a Nocardia species

1976 • 93 citations

The Reactivity of Nucleophilic Reagents with Furoyl-chymotrypsin

1965 • 92 citations

Structures of olivanic acid derivatives MM 4550 and MM 13902; two new, fused β-lactams isolated from Streptomyces olivaceus

1977 • 88 citations

Acquisition of substrate-specific parameters during the catalytic reaction of penicillinase.

1976 • 85 citations

Vinylogous imides. II. Ultraviolet spectra and the application of Woodward's rules

1970 • 69 citations

Directed selective pressure on a β-lactamase to analyse molecular changes involved in development of enzyme function

1976 • 69 citations

Effect of Pencillinase on the Activity of Penicillins: Synergistic Activity of Penicillins against Penicillinase-producing Gram-negative Bacilli

1964 • 67 citations

Inhibition of β-Lactamases by β-Lactam Antibiotics

1972 • 57 citations

Preparation of gram quantities of a purified R-factor-mediated penicillinase from Escherichia coli strain W3310

1972 • 48 citations

Evidence for the Formation of Hippuryl Chymotrypsin during the Hydrolysis of Hippuric Acid Esters

1963 • 46 citations

Inhibition of the β-lactamases of Escherichia coli and Klebsiella aerogenes by semi-synthetic penicillins

1972 • 41 citations

Effect of Pencillinase on the Activity of Penicillins: Potentiation of Penicillin Action by Inhibition of Penicillinase

1964 • 36 citations

Degradation of penicillin G methyl ester with trifluoroacetic acid

1972 • 29 citations

Superactivation of neutral proteases: acylation with N-hydroxysuccinimide esters

1976 • 26 citations

Potent Combinations of <i>β</i>-Lactam Antibiotics using the <i>β</i>-Lactamase Inhibition Principle

1975 • 15 citations