Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

1989 • 1,443 citations

Chemistry and biology of pteridines

1956 • 1,263 citations

An L-arginine/nitric oxide pathway present in human platelets regulates aggregation.

1990 • 1,209 citations

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase

1987 • 896 citations

Analysis of reduced forms of biopterin in biological tissues and fluids

1980 • 713 citations

Macrophage Oxidation of L-Arginine to Nitric Oxide, Nitrite, and Nitrate

1989 • 681 citations

Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.

1991 • 599 citations

Reduced Biopterin as a Cofactor in the Generation of Nitrogen Oxides by Murine Macrophages

1989 • 571 citations

BIOSYNTHESIS AND METABOLISM OF TETRAHYDROBIOPTERIN AND MOLYBDOPTERIN

1985 • 542 citations

Signal transduction mechanisms involving nitric oxide

1991 • 538 citations

Calcium‐dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin

1990 • 507 citations

Purification of a Ca²⁺/calmodulin‐dependent nitric oxide synthase from porcine cerebellum

1990 • 433 citations

Brain nitric oxide synthase is a biopterin‐ and flavin‐containing multi‐functional oxido‐reductase

1991 • 422 citations

Nitric oxide synthase: Irreversible inhibition by L-N -Nitroarginine in brain and

1991 • 368 citations

Chemistry and biology of pteridines 1986

1987 • 335 citations

Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts.

1990 • 288 citations

Biosynthesis of endothelium-derived relaxing factor: A cytosolic enzyme in porcine aortic endothelial cells Ca2+-dependently converts L-arginine into an activator of soluble guanylyl cyclase

1989 • 271 citations

Nitric oxide from L-arginine stimulates the soluble guanylate cyclase in adrenal glands

1989 • 238 citations

Kinetic characteristics of nitric oxide synthase from rat brain

1990 • 210 citations

Endothelium‐derived relaxing factor and atriopeptin II elevate cyclic GMP levels in pig aortic endothelial cells

1988 • 130 citations

Simultaneous determination of neopterin and creatinine in serum with solid-phase extraction and on-line elution liquid chromatography.

1987 • 102 citations

Effect of calcium on endothelium-derived relaxing factor formation and cGMP levels in endothelial cells

1989 • 92 citations

Biopterin

1978 • 85 citations

CFS hydroxylase cofactor levels in some neurological diseases.

1980 • 74 citations

Serum Aluminum Levels and Erythrocyte Dihydropteridine Reductase Activity in Patients on Hemodialysis

1987 • 72 citations

Ca²⁺‐dependent formation of an L‐arginine‐derived activator of soluble guanylyl cyclase in bovine lung

1989 • 37 citations

The effects of pathological and normal physiological processes on biopterin derivative levels in man

1980 • 36 citations

Establishment of a Human Cell Line Highly Expressing Endothelin in Serum-Free Medium

1991 • 7 citations