Glutaric aciduria type I: Pathomechanisms of neurodegeneration

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

A simple method for organotypic cultures of nervous tissue

1991 • 3,075 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1987 • 1,280 citations

The release and uptake of excitatory amino acids

1990 • 1,090 citations

Organotypic monolayer cultures of nervous tissue

1981 • 862 citations

Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system

1971 • 808 citations

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1991 • 554 citations

Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity

1998 • 538 citations

NMDA Receptor Heterogeneity During Postnatal Development of the Rat Brain: Differential Expression of the NR2A, NR2B, and NR2C Subunit Proteins

1997 • 439 citations

Continuous monitoring of ATP-converting reactions by purified firefly luciferase

1976 • 318 citations

AMINO ACIDS AS CENTRAL NERVOUS TRANSMITTERS: THE INFLUENCE OF IONS, AMINO ACID ANALOGUES, AND ONTOGENY ON TRANSPORT SYSTEMS for <scp>l</scp>‐GLUTAMIC AND <scp>l</scp>‐ASPARTIC ACIDS AND GLYCINE INTO CENTRAL NERVOUS SYNAPTOSOMES OF THE RAT¹

1973 • 261 citations

Development of the hippocampus in vitro: Cell types, synapses and receptors

1984 • 210 citations

Glutaric aciduria: Biochemical and morphologic considerations

1977 • 196 citations

Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures

1991 • 175 citations

Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition.

1991 • 157 citations

Neurotoxicity at the N‐Methyl‐D‐Aspartate Receptor in Energy‐Compromised Neurons An Hypothesis for Cell Death in Aging and Disease

1989 • 157 citations

The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed MK-801

1992 • 140 citations

Evidence that the Loss of the Voltage‐Dependent Mg²⁺ Block at the N‐Methyl‐D‐Aspartate Receptor Underlies Receptor Activation During Inhibition of Neuronal Metabolism

1992 • 137 citations

Topical Review: Glutamate in Neurologic Diseases

1997 • 129 citations

Glutaric acidemia

1980 • 113 citations

Formation of layer-specific fiber projections to the hippocampus in vitro.

1993 • 109 citations

Inhibition of brain glutamate decarboxylase by glutarate, glutaconate, and β-Hydroxyglutarate: Explanation of the symptoms in glutaric aciduria?

1976 • 92 citations

Glutamate and γ‐Aminobutyric Acid Neurotransmitter Systems in the Acute Phase of Maple Syrup Urine Disease and Citrullinemia Encephalopathies in Newborn Calves

1992 • 77 citations

Hypothesis: A Role for Quinolinic Acid in the Neuropathology of Glutaric Aciduria Type I

1987 • 69 citations

Improved assay of glutaryl-CoA dehydrogenase in cultured cells and liver: application to glutaric aciduria type I

1983 • 61 citations

Nerve cell lesions caused by 3‐hydroxyglutaric acid: A possible mechanism for neurodegeneration in glutaric acidaemia I

1997 • 59 citations

Striatal degeneration and spongy myelinopathy in glutaric acidemia

1992 • 55 citations

Role of excitotoxins in developmental neuropathology.

1993 • 46 citations

Homocysteic and homocysteine sulphinic acid exhibit excitotoxicity in organotypic cultures from rat brain

1998 • 39 citations

Glutaric Aciduria Type 1 - An Atypical Presentation Together with some Observations upon Treatment and the Possible Cause of Cerebral Damage

1992 • 37 citations

Ketotic Episodes in Glutaryl-CoA Dehydrogenase Deficiency (Glutaric Aciduria)

1979 • 32 citations

Some chemical highlights in the development of excitatory amino acid pharmacology

1991 • 31 citations

The inhibition of mouse brain glutamate decarboxylase by some structural analogues of L-glutamic acid

1977 • 31 citations

Prenatal Diagnosis of Inherited Metabolic Disorders by Stable Isotope Dilution GC‐MS Analysis of Metabolites in Amniotic Fluid: Review of Four Years Experience

1989 • 25 citations

Regulation of Mitochondrial ATP Synthase Activity in Human Myocardium

1998 • 22 citations

Effects of the epileptogenic agent bicuculline methiodide on membrane currents induced byN-methyl-d-aspartate and kainate (oocyte;Xenopus laevis)

1994 • 12 citations

NMDA receptor levels in chronically depolarized long‐term neonatal rat neocortical explants

1992 • 9 citations

Deficiency of pyrimidine 5′‐nucleotidase in human leukocytes

1988 • 8 citations