Increased levels of oxidized glutathione in CD4+ lymphocytes associated with disturbed intracellular redox balance in human immunodeficiency virus type 1 infection

1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults

1993 • 3,829 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

Oxidative stress as a mediator of apoptosis

1994 • 2,210 citations

Glutathione metabolism and its selective modification.

1988 • 1,975 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

1981 • 1,366 citations

Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

1990 • 960 citations

Regulation of cellular glutathione

1989 • 851 citations

ROLE OF REVERSIBLE OXIDATION-REDUCTION OF ENZYME THIOLS-DISULFIDES IN METABOLIC REGULATION

1985 • 840 citations

Glutathione-ascorbic acid antioxidant system in animals

1994 • 825 citations

SYSTEMIC GLUTATHIONE DEFICIENCY IN SYMPTOM-FREE HIV-SEROPOSITIVE INDIVIDUALS

1989 • 725 citations

Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma

1992 • 503 citations

Functions of glutathione and glutathione disulfide in immunology and immunopathology

1994 • 446 citations

Glutathione, free radicals and chemotherapeutic agents

1988 • 393 citations

Low Concentrations of Acid-Soluble Thiol (Cysteine) in the Blood Plasma of HIV-1-Infected Patients

1989 • 349 citations

Serum Levels of Tumor Necrosis Factor- (TNF ) and Soluble TNF Receptors in Human Immunodeficiency Virus Type 1 Infection-Correlations to Clinical, Immunologic, and Virologic Parameters

1994 • 302 citations

Toxicity of thiols and disulphides: Involvement of free-radical species

1989 • 296 citations

HIV-induced cysteine deficiency and T-cell dysfunction — a rationale for treatment with N-acetylcysteine

1992 • 254 citations

Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx.

1994 • 220 citations

Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxidase deficiency.

1994 • 205 citations

Invited Commentary is Apoptosis Mediated by Reactive Oxygen Species?

1994 • 201 citations

Determination of reduced, oxidized, and protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography

1990 • 171 citations

Intracellular Glutathione Levels in T Cell Subsets Decrease in HIV-Infected Individuals

1992 • 161 citations

N-Acetylcysteine: A New Approach to Anti-HIV Therapy

1992 • 157 citations

The role of glutathione in lymphocyte activation. I. Comparison of inhibitory effects of buthionine sulfoximine and 2-cyclohexene-1-one by nuclear size transformation.

1985 • 153 citations

Glutathione depletion in HIV-infected patients: role of cysteine deficiency and effect of oral N-acetylcysteine.

1992 • 148 citations

CD4 and CD8 T cells with high intracellular glutathione levels are selectively lost as the HIV infection progresses

1991 • 145 citations

Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction.

1994 • 113 citations

Programmed cell death (apoptosis) and cell survival regulation: relevance to AIDS and cancer

1994 • 111 citations

Tumor necrosis factor-alpha-mediated decrease in glutathione increases the sensitivity of pulmonary vascular endothelial cells to H2O2.

1992 • 107 citations

Functional properties of CD19 B lymphocytes positively selected from buffy coats by immunomagnetic separation

1990 • 104 citations

Thiol reagents increase the affinity of the inositol 1,4,5-trisphosphate receptor

1993 • 97 citations

Gluthatione Augments the Activation of Cytotoxic T Lymphocytes in vivo

1986 • 94 citations

Abnormal Amino-Acid Concentrations in the Blood of Patients with Acquired Immunodeficiency Syndrome (AIDS) May Contribute to the Immunological Defect

1988 • 90 citations

Reactive oxygen species, antioxidants, and acquired immunodeficiency syndrome. Sense or speculation?

1991 • 87 citations

Direct immunomagnetic quantification of lymphocyte subsets in blood.

1988 • 78 citations

Demonstration and partial characterization of glutathione disulfide-stimulated ATPase activity in the plasma membrane fraction from rat hepatocytes.

1985 • 77 citations

Requirement of thiol compounds as reducing agents for IL-2-mediated induction of LAK activity and proliferation of human NK cells.

1993 • 63 citations

Changes in plasma amino acid concentrations in response to HIV-1 infection

1994 • 63 citations

Dysregulation of Adult T-Cell Leukemia-Derived Factor (ADF)/Thioredoxin in HIV Infection: Loss of ADF High-Producer Cells in Lymphoid Tissues of AIDS Patients

1992 • 54 citations

Application of reversed-phase high-performance liquid chromatography using pre-column derivatization with o-phthaldialdehyde for the quantitative analysis of amino acids in adult and fetal sheep plasma, animal feeds and tissues

1984 • 50 citations

Interleukin-6 as a mediator responsible for inflammation-induced increase in plasma angiotensinogen.

1993 • 38 citations

Reactive oxygen species, antioxidants, and acquired immunodeficiency syndrome. Sense or speculation?

1991 • 36 citations

Monochlorobimane Does Not Selectively Label Glutathione in Peripheral Blood Mononuclear Cells

1994 • 34 citations

T4⁺ cell numbers are correlated with plasma glutamate and cystine levels: association of hyperglutamataemia with immunodeficiency in diseases with different aetiologies

1992 • 31 citations

Effect of oxidant exposure on thiol status in the intestinal mucosa

1993 • 24 citations

Induction of intracellular glutathione in alveolar type II pneumocytes following BCNU exposure

1994 • 16 citations

Tumor necrosis factor-induced lung injury is not mediated by platelet-activating factor

1989 • 14 citations

Intra- and interlaboratory quality control for assay of amino acids in biological fluids: 14 years of the French experience

1993 • 12 citations