Immune Activation and Decreased Tryptophan in Patients with HIV-1 Infection

Neopterin as a marker for activated cell-mediated immunity: Application in HIV infection

1988 • 573 citations

II. Excitotoxic models for neurodegenerative disorders

1984 • 469 citations

Neurological and neuropshychological manifestations of HIV‐1 infection: Association with AIDS‐related complex but not asymptomatic HIV‐1 infection

1989 • 206 citations

Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms.

1990 • 203 citations

Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome

1989 • 190 citations

Human macrophages degrade tryptophan upon induction by interferon-gamma

1987 • 182 citations

Induction of Tryptophan DegradationIn VitroandIn Vivo: A γ-Interferon-Stimulated Activity

1986 • 181 citations

Interferon-gamma concentrations are increased in sera from individuals infected with human immunodeficiency virus type 1.

1989 • 119 citations

Tumour Necrosis Factor-α and Lipopolysaccharide Enhance Interferon-Induced Tryptophan Degradation and Pteridine Synthesis in Human Cells

1989 • 113 citations

Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1

1989 • 110 citations

Elevated neopterin and beta2-microglobulin levels in blood and cerebrospinal fluid occur early in HIV-1 infection

1989 • 88 citations

Tryptophan Degradation in Patients Infected by Human Immunodeficiency Virus

1988 • 83 citations

Natural antibodies to IFN-gamma in man and their increase during viral infection.

1990 • 71 citations

Indole amine deficiency in blood and cerebrospinal fluid from patients with human immunodeficiency virus infection

1989 • 54 citations

Association between intrathecal anti-HIV-1 immunoglobulin G synthesis and occurrence of HIV-1 in cerebrospinal fluid

1989 • 32 citations