Role of phosphodiesterase in regulation of calcium current in isolated cardiac myocytes.

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Calcium channel modulation by neurotransmitters, enzymes and drugs

1983 • 1,267 citations

Calcium Channels in Excitable Cell Membranes

1983 • 725 citations

Cyclic GMP Metabolism and Involvement in Biological Regulation

1977 • 629 citations

The dependence of slow inward current in Purkinje fibres on the extracellular calcium‐concentration

1967 • 544 citations

Mechanisms of calcium channel modulation by β-adrenergic agents and dihydropyridine calcium agonists

1986 • 493 citations

Existence and role of a slow inward current during the frog atrial action potential

1969 • 449 citations

Membrane calcium current in ventricular myocardial fibres

1970 • 401 citations

Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells

1986 • 338 citations

Cyclic AMP and contractile activity in heart.

1977 • 291 citations

On the mechanism of muscarinic inhibition of the cardiac Ca current

1986 • 283 citations

Stimulation of Adenosine 3',5'-Monophosphate Hydrolysis by Guanosine 3',5'-Monophosphate

1971 • 275 citations

Effects of Intracellular Free Magnesium on Calcium Current in Isolated Cardiac Myocytes

1988 • 218 citations

Coexistence of Guanylate Cyclase and Atrial Natriuretic Factor Receptor in a 180-kD Protein

1987 • 218 citations

Cyclic guanosine 3',5'‐monophosphate regulates the calcium current in single cells from frog ventricle.

1987 • 199 citations

Slow inward current and its role mediating the chronotropic effect of epinephrine in the rabbit sinoatrfal node

1980 • 163 citations

Ion Channels in Cardiac Cell Membranes

1984 • 148 citations

Membrane potential and slow inward current dependence of frog cardiac mechanical activity

1972 • 130 citations

Identification and characterization of both the cytosolic and particulate forms of cyclic GMP-stimulated cyclic AMP phosphodiesterase from rat liver

1986 • 73 citations

Evidence that cyclic GMP may regulate cyclic AMP metabolism in the isolated frog ventricle

1981 • 40 citations

Nature of the inhibitory effect of collagenase on phosphodiesterase activity.

1985 • 11 citations