Targeted disruption within the CD3 zeta/eta/phi/Oct-1 locus in mouse.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1988 • 671 citations

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens

1978 • 589 citations

Surface Antigen Expression and Immunoglobulin Gene Rearrangement During Mouse pre‐B Cell Development

1983 • 490 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

Identification of the components of the murine T cell antigen receptor complex

1985 • 333 citations

The Developmental Biology of T Lymphocytes

1988 • 300 citations

Molecular Cloning of the Zeta Chain of the T Cell Antigen Receptor

1988 • 275 citations

Teratocarcinomas and Embryonic Stem Cells: A Practical Approach

1988 • 263 citations

Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs.

1989 • 257 citations

Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors

1990 • 249 citations

T cell development in mice lacking the CD3-zeta/eta gene.

1993 • 235 citations

The Human T-Cell Receptor

1984 • 232 citations

The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells

1986 • 225 citations

Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family.

1990 • 225 citations

T Cell Development in Mice that Lack the ζ Chain of the T Cell Antigen Receptor Complex

1993 • 217 citations

The γδT Cell Receptor

1988 • 214 citations

High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61.

1985 • 203 citations

Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor.

1991 • 180 citations

Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

1993 • 164 citations

Disulfide linkage of the zeta and eta chains of the T cell receptor. Possible identification of two structural classes of receptors.

1988 • 146 citations

The implications of subunit interactions for the structure of the T cell receptor‐CD3 complex

1990 • 130 citations

Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex.

1991 • 129 citations

Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.

1989 • 118 citations

Structure of the T-cell antigen receptor: evidence for two CD3 epsilon subunits in the T-cell receptor-CD3 complex.

1990 • 110 citations

Activation-Driven Programmed Cell Death and T Cell Receptor ζη Expression

1989 • 98 citations

Molecular cloning of the CD3 eta subunit identifies a CD3 zeta-related product in thymus-derived cells.

1990 • 92 citations

Biochemical Characterization of the η Chain of the T-cell Receptor

1989 • 80 citations

The Isolation and Characterization of the Murine T Cell Antigen Receptor ζ Chain Gene

1989 • 76 citations

T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes.

1992 • 72 citations

CD3 eta and CD3 zeta are alternatively spliced products of a common genetic locus and are transcriptionally and/or post-transcriptionally regulated during T-cell development.

1991 • 58 citations

The high affinity Fc epsilon receptor gamma subunit (Fc epsilon RI gamma) facilitates T cell receptor expression and antigen/major histocompatibility complex-driven signaling in the absence of CD3 zeta and CD3 eta

1991 • 50 citations

Organization of the human T cell receptor zeta/eta gene and its genetic linkage to the Fc gamma RII-Fc gamma RIII gene cluster.

1992 • 47 citations

Differential signal transduction via T-cell receptor CD3 zeta 2, CD3 zeta-eta, and CD3 eta 2 isoforms.

1991 • 38 citations

Targeted disruption within the CD3 zeta/eta/phi/Oct-1 locus in mouse.

1994 • 34 citations

CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1.

1993 • 26 citations

CD3ζ and η chains are produced by alternative splicing from a common gene

1990 • 26 citations

Characterization of thymus-derived lymphocytes expressing Ti alpha-beta CD3 gamma delta epsilon zeta-zeta, Ti alpha-beta CD3 gamma delta epsilon eta-eta or Ti alpha-beta CD3 gamma delta epsilon zeta-zeta/zeta-eta antigen receptor isoforms: analysis by gene transfection.

1990 • 25 citations

A fraction of CD3 epsilon subunits exists as disulfide-linked dimers in both human and murine T lymphocytes.

1990 • 24 citations

Differential regulation of T-cell receptor processing and surface expression affected by CD3 theta, an alternatively spliced product of the CD3 zeta/eta gene locus.

1992 • 21 citations

Overexpression of CD3 eta during thymic development does not alter the negative selection process.

1993 • 8 citations

Human genomic sequences corresponding to murine CD3η‐related transcripts: Lack of conservation or expression of homologous human products

1992 • 8 citations

T cell antigen receptor-eta subunit. Low levels of expression and limited cross-species conservation.

1993 • 5 citations