Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Metabolism of Isolated Fat Cells

1964 • 4,431 citations

Omega-3 fatty acids in health and disease and in growth and development

1991 • 2,179 citations

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

1995 • 2,036 citations

Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action

1995 • 1,630 citations

The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and Lipolysis

1964 • 1,401 citations

Fish oils and plasma lipid and lipoprotein metabolism in humans: a critical review.

1989 • 1,152 citations

Transient increase in obese gene expression after food intake or insulin administration

1995 • 1,102 citations

TRANSCRIPTIONAL REGULATION OF GENE EXPRESSION DURING ADIPOCYTE DIFFERENTIATION

1995 • 1,033 citations

Cellular and Molecular Aspects of Adipose Tissue Development

1992 • 671 citations

Fish Oil Prevents Insulin Resistance Induced by High-Fat Feeding in Rats

1987 • 658 citations

Increased obese mRNA expression in omental fat cells from massively obese humans

1995 • 527 citations

Biochemistry and physiology of n‐3 fatty acids

1992 • 321 citations

Peritz' F test: Basic program of a robust multiple comparison test for statistical analysis of all differences among group means

1984 • 305 citations

Dietary Polyunsaturated Fatty Acid Regulation of Gene Transcription

1994 • 305 citations

The adipocyte: Storage depot or node on the energy information superhighway?

1995 • 298 citations

Coordinate regulation of glycolytic and lipogenic gene expression by polyunsaturated fatty acids.

1994 • 297 citations

Dietary fat: exogenous determination of membrane structure and cell function

1991 • 272 citations

Control of adipocyte differentiation

1995 • 262 citations

Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression.

1991 • 248 citations

Effects of fish oil on VLDL triglyceride kinetics in humans

1990 • 214 citations

Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats.

1993 • 204 citations

Lipid accumulation and body fat distribution is influenced by type of dietary fat fed to rats.

1993 • 198 citations

Fish oil n-3 fatty acids selectively limit the hypertrophy of abdominal fat depots in growing rats fed high-fat diets

1993 • 193 citations

Polyunsaturated fatty acids inhibit S14 gene transcription in rat liver and cultured hepatocytes.

1993 • 146 citations

Regulation of gene transcription by polyunsaturated fatty acids

1993 • 139 citations

Development of dietary obesity in rats: influence of amount and composition of dietary fat.

1992 • 138 citations

Dietary fish oils limit adipose tissue hypertrophy in rats

1990 • 133 citations

Transcriptional Control of the Stearoyl-CoA Desaturase-1 Gene by Polyunsaturated Fatty Acids1

1994 • 131 citations

Regulation of Rat Liver Apolipoprotein A‐I, Apolipoprotein A‐II and Acyl‐Coenzyme A Oxidase Gene Expression by Fibrates and Dietary Fatty Acids

1995 • 121 citations

Cyclic AMP and Fatty Acids Increase Carnitine Palmitoyltransferase I Gene Transcription in Cultured Fetal Rat Hepatocytes

1996 • 121 citations

Regional variation in adipose tissue lipolysis in lean and obese men.

1991 • 117 citations

The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis

1993 • 116 citations

Serum lipids, hepatic glycerolipid metabolism and peroxisomal fatty acid oxidation in rats fed ω-3 and ω-6 fatty acids

1992 • 114 citations

Evidence for mechanisms of the hypotriglyceridemic effect of n − 3 polyunsaturated fatty acids

1992 • 97 citations

Dietary supplementation of very long-chain n-3 fatty acids decreases whole body lipid utilization in the rat

1993 • 93 citations

Early and late stimulation of ob mRNA expression in meal-fed and overfed rats.

1996 • 91 citations

Pharmacologic Manipulation of ob Expression in a Dietary Model of Obesity

1996 • 86 citations

Regulation of adipose cell differentiation. II. Kinetics of induction of the aP2 gene by fatty acids and modulation by dexamethasone.

1991 • 79 citations

Regulation of hormone-sensitive lipase during fasting

1994 • 78 citations

Biological effects of fish oils in relation to chronic diseases

1986 • 75 citations

Differential response of preadipocytes and adipocytes to prostacyclin and prostaglandin E2: physiological implications.

1992 • 72 citations

Regional differences in triacylglycerol synthesis in adipose tissue and in cultured preadipocytes.

1993 • 70 citations

Adipose tissues from various anatomical sites are characterized by different patterns of gene expression and regulation

1993 • 68 citations

Are the n-3 fatty acids from dietary fish oil deposited in the triglyceride stores of adipose tissue?

1990 • 67 citations

Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes

1995 • 58 citations

Effects of Polyunsaturated Fats on Blood Pressure

1993 • 54 citations

Fatty Acids and Fibrates are Potent Inducers of Transcription of the Phosphenol pyruvate Carboxykinase Gene in Adipocytes

1995 • 53 citations

Individual fish-oil n−3 polyunsaturated fatty acid deposition and mobilization rates for adipose tissue of rats in a nutritional steady state

1994 • 46 citations

Effects of a fish oil-lard diet on rat plasma lipoproteins, liver FAS, and lipolytic enzymes

1994 • 46 citations

Effect of diets rich in medium‐chain and long‐chain triglycerides on lipogenic‐enzyme gene expression in liver and adipose tissue of the weaned rat

1992 • 40 citations

Augmented expression of obese (ob) gene during the process of obesity in genetically obese‐hyperglycemic Wistar fatty (falfa) rats

1996 • 29 citations