Thyromimetic mode of action of peroxisome proliferators: activation of ‘malic’ enzyme gene transcription

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

1992 • 1,751 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene.

1992 • 903 citations

Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators.

1986 • 328 citations

The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid omega-hydroxylase, by clofibric acid.

1992 • 312 citations

Functional relationship of thyroid hormone-induced lipogenesis, lipolysis, and thermogenesis in the rat.

1991 • 271 citations

Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase.

1987 • 206 citations

Two -acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene

1991 • 198 citations

Identification of a thyroid hormone response element in the malic enzyme gene.

1990 • 182 citations

The peroxisome proliferator activated receptor regulates malic enzyme gene expression.

1994 • 157 citations

Plasma Lipoproteins and Regulation of Hepatic Metabolism of Fatty Acids in Altered Thyroid States*

1985 • 155 citations

Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element.

1991 • 134 citations

A novel heterodimerization partner for thyroid hormone receptor. Peroxisome proliferator-activated receptor.

1994 • 132 citations

A thyromimetic that decreases plasma cholesterol levels without increasing cardiac activity

1986 • 129 citations

THE SHORT‐ AND LONG‐TERM EFFECTS OF BEZAFIBRATE IN THE RAT*

1982 • 127 citations

Sequences within the 5′-flanking region of the S14 gene confer responsiveness to glucose in primary hepatocytes

1989 • 115 citations

Identification of multiple thyroid hormone response elements located far upstream from the rat S14 promoter.

1990 • 113 citations

Transcriptional activation and stabilization of malic enzyme mRNA precursor by thyroid hormone.

1988 • 84 citations

Thyromimetic effect of peroxisomal proliferators in rat liver

1991 • 63 citations

Coding nucleotide sequence of rat liver malic enzyme mRNA.

1986 • 63 citations

A single amino acid change in the mouse peroxisome proliferator-activated receptor alpha alters transcriptional responses to peroxisome proliferators.

1995 • 46 citations

The induction of liver peroxisomal proliferation by β,β′-methyl-substituted hexadecanedioic acid (MEDICA 16)

1988 • 45 citations

Structural and functional analysis of the rat malic enzyme gene promoter.

1988 • 39 citations

Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbAα2 and peroxisome proliferator-activated receptor: evidence for different mechanisms of inhibition

1995 • 32 citations

Thyroid Hormone-mediated Transcriptional Activation of the Rat Liver Malic Enzyme Gene by Dehydroepiandrosterone

1989 • 31 citations

Tissue selective modulation of redox and phosphate potentials by beta,beta'-methyl-substituted hexadecanedioic acid.

1992 • 21 citations

Effect of thyroid hormone treatment on redox and phosphate potentials in rat liver.

1992 • 20 citations