Noninvasive Diagnosis of Renal-Allograft Rejection by Measurement of Messenger RNA for Perforin and Granzyme B in Urine

Longitudinal data analysis using generalized linear models

1986 • 17,084 citations

SAS System for Mixed Models

1996 • 10,609 citations

The Banff 97 working classification of renal allograft pathology

1999 • 3,028 citations

Improved Graft Survival after Renal Transplantation in the United States, 1988 to 1996

2000 • 1,803 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells

1994 • 844 citations

LRISK FACTORS FOR CHRONIC REJECTION IN RENAL ALLOGRAFT RECIPIENTS

1993 • 684 citations

Molecular Mechanisms of Lymphocyte-Mediated Cytotoxicity and Their Role in Immunological Protection and Pathogenesis In Vivo

1996 • 614 citations

The UNOS Scientific Renal Transplant Registry.

1999 • 580 citations

Beneficial effects of treatment of early subclinical rejection

1998 • 463 citations

Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation

1997 • 437 citations

Lymphocyte-mediated cytotoxicity: Two pathways and multiple effector molecules

1994 • 414 citations

Granzymes: exogenous porteinases that induce target cell apoptosis

1995 • 403 citations

DELETERIOUS EFFECTS OF DELAYED GRAFT FUNCTION IN CADAVERIC RENAL TRANSPLANT RECIPIENTS INDEPENDENT OF ACUTE REJECTION1,2,3

1998 • 381 citations

Perforin: structure and function

1995 • 361 citations

Evaluation of pathologic criteria for acute renal allograft rejection

1997 • 284 citations

THE IMPACT OF ACUTE REJECTION EPISODES ON LONG-TERM GRAFT FUNCTION AND OUTCOME IN 1347 PRIMARY RENAL TRANSPLANTS TREATED BY 3 CYCLOSPORINE REGIMENS

1993 • 268 citations

HISTOLOGICAL FINDINGS IN EARLY ROUTINE BIOPSIES OF STABLE RENAL ALLOGRAFT RECIPIENTS

1994 • 245 citations

Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction.

1991 • 206 citations

THE INCIDENCE AND IMPACT OF EARLY REJECTION EPISODES ON GRAFT OUTCOME IN RECIPIENTS OF FIRST CADAVER KIDNEY TRANSPLANTS

1992 • 203 citations

Identity and Cytotoxic Capacity of Cells Infiltrating Renal Allografts

1975 • 169 citations

A prospective randomized trial of three different sizes of core-cutting needle for renal transplant biopsy

2000 • 165 citations

Heightened intragraft CTL gene expression in acutely rejecting renal allografts.

1994 • 164 citations

Cytotoxic T Lymphocyte-assisted Suicide

1998 • 161 citations

MOLECULAR EXECUTORS OF CELL DEATH-DIFFERENTIAL INTRARENAL EXPRESSION OF Fas LIGAND, Fas, GRANZYME B, AND PERFORIN DURING ACUTE AND/OR CHRONIC REJECTION OF HUMAN RENAL ALLOGRAFTS1,2

1996 • 152 citations

Acute rejection of vascular heart allografts by perforin‐deficient mice

1995 • 99 citations

Histopathological concordance of paired renal allograft biopsy cores. Effect on the diagnosis and management of acute rejection.

1995 • 72 citations

SAFETY OF KIDNEY BIOPSY IN PEDIATRIC TRANSPLANTATION

1999 • 72 citations

Analysis of factors associated with complications following renal transplant needle core biopsy

1994 • 65 citations

Unlocking the secrets of CTL and NK cells

1995 • 65 citations

HISTOPATHOLOGICAL CONCORDANCE OF PAIRED RENAL ALLOGRAFT BIOPSY CORES

1995 • 61 citations

Granzyme B and perforin can be used as predictive markers of acute rejection in heart transplantation

1994 • 57 citations

PERFORIN AND GRANZYME B EXPRESSION IS ASSOCIATED WITH SEVERE ACUTE REJECTION

1994 • 49 citations

Percutaneous Needle Biopsy of the Transplanted Kidney: Technique and Complications

1989 • 44 citations

Expression of the cytotoxic T cell mediator granzyme B during liver allograft rejection

1995 • 43 citations

Correlation of histology to clinical rejection reversal: A Thymoglobulin Multicenter Trial report

1999 • 41 citations

EXCELLENT OUTCOME WITH A CALCIUM CHANNEL BLOCKER—SUPPLEMENTED IMMUNOSUPPRESSIVE REGIMEN IN CADAVERIC RENAL TRANSPLANTATION

1993 • 37 citations

THE RELATIONSHIP OF GRANZYME A AND PERFORIN EXPRESSION TO CARDIAC ALLOGRAFT REJECTION AND DYSFUNCTION1

1995 • 27 citations

Dual mechanisms of lymphocytemediated cytotoxicity serve to control and deliver the immune response

1995 • 13 citations