Suicidal gene therapy for pleural metastasis of lung cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

1992 • 1,530 citations

Systemic Gene Expression After Intravenous DNA Delivery into Adult Mice

1993 • 725 citations

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

1995 • 700 citations

Curability of Tumors Bearing Herpes Thymidine Kinase Genes Transfered by Retroviral Vectors

1990 • 514 citations

In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats.

1993 • 442 citations

Gene Therapy for the Treatment of Brain Tumors Using Intra-Tumoral Transduction with the Thymidine Kinase Gene and Intravenous Ganciclovir. National Institutes of Health

1993 • 420 citations

9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication.

1983 • 384 citations

Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component.

1994 • 308 citations

The treatment of malignant pleural effusions

1974 • 293 citations

Indications for pleurectomy in malignant effusion

1975 • 214 citations

Therapeutic Effect of a Retroviral Wild-Type p53 Expression Vector in an Orthotopic Lung Cancer Model

1994 • 214 citations

Gene therapy of maliganant brain tumors: A rat glioma line bearing the herpes simplex virus type 1‐thymidine kinase gene and wild type retrovirus kills other tumor cells

1992 • 170 citations

Liposome-mediated in vivo gene transfer of antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity.

1995 • 152 citations

Introduction and Expression of the Human Insulin Gene in Adult Rat Liver

1989 • 140 citations

Gene therapy approaches for inherited and acquired lung diseases.

1996 • 95 citations

Cationic lipids for reporter gene and CFTR transfer to rat pulmonary epithelium.

1995 • 89 citations

Gene Therapy for Peritoneal Dissemination of Pancreatic Cancer by Liposome-Mediated Transfer of Herpes Simplex Virus Thymidine Kinase Gene

1997 • 88 citations

Modification of Tumor Suppressor Gene Expression and Induction of Apoptosis in Non-Small Cell Lung Cancer (NSCLC) with an Adenovirus Vector Expressing Wildtype p53 and Cisplatin. University of Texas M.D. Anderson Cancer Center, Houston, Texas

1996 • 52 citations

Use of von Willebrand Factor Promoter to Transduce Suicidal Gene to Human Endothelial Cells, HUVEC

1996 • 38 citations

Safety of Intrapleurally Administered Recombinant Adenovirus Carrying Herpes Simplex Thymidine Kinase DNA Followed by Ganciclovir Therapy in Nonhuman Primates

1996 • 37 citations

Malignant effusions: Diagnostic evaluation and therapeutic strategy

1981 • 36 citations

In Vivo Transfer and Expression of the lacZ Gene in the Mouse Lung

1993 • 35 citations

Orthotopic growth and metastasis of human non-small cell lung carcinoma cells injected into the pleural cavity of nude mice

1998 • 22 citations