Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer

Apoptosis by Death Factor

1997 • 5,038 citations

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1997 • 2,746 citations

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity

1995 • 1,306 citations

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

1993 • 857 citations

Cell Surface Trafficking of Fas: A Rapid Mechanism of p53-Mediated Apoptosis

1998 • 752 citations

FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas

1995 • 702 citations

Purification and characterization of the Fas-ligand that induces apoptosis.

1994 • 521 citations

FasGene Mutations in the Canale–Smith Syndrome, an Inherited Lymphoproliferative Disorder Associated with Autoimmunity

1996 • 486 citations

Anti-Fas on nonhematopoietic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness.

1994 • 262 citations

Identification and characterisation of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene

1997 • 248 citations

Mutations in the Fas Antigen in Patients With Multiple Myeloma

1997 • 228 citations

Mutation analysis of the PTEN/MMAC1 gene in lung cancer

1998 • 198 citations

Spontaneous Development of Plasmacytoid Tumors in Mice with Defective Fas–Fas Ligand Interactions

1998 • 181 citations

Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis.

1997 • 177 citations

PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers

1998 • 170 citations

Missense Mutations in the Fas Gene Resulting in Autoimmune Lymphoproliferative Syndrome: A Molecular and Immunological Analysis

1997 • 168 citations

A simple, precise and economical microdissection technique for analysis of genomic DNA from archival tissue sections

1998 • 150 citations

Inactivation of thePTEN/MMAC1/TEP1 gene in human lung cancers

1998 • 143 citations

CD95 (APO-1/Fas) Mutations in Childhood T-Lineage Acute Lymphoblastic Leukemia

1998 • 121 citations

Infrequent Genetic Alterations of the PTEN/MMAC1 Gene in Japanese Patients with Primary Cancers of the Breast, Lung, Pancreas, Kidney, and Ovary

1997 • 107 citations

Lack of cell surface Fas/APO-1 expression in pulmonary adenocarcinomas.

1998 • 91 citations

Distinct regions of allelic imbalance on chromosome 10q22-q26 in squamous cell carcinomas of the lung

1998 • 48 citations

Detection of polymorphisms within the FAS cDNA gene sequence by GC-clamp denaturing gradient gel eletrophoresis

1994 • 48 citations

Somatic Fas Mutations in Non-Hodgkin’s Lymphoma: Association With Extranodal Disease and Autoimmunity

1998 • 26 citations

Mutation of CD95 (Fas/Apo-1) Gene in Adult T-Cell Leukemia Cells

1998 • 12 citations