Effects of Misspecifying Genetic Parameters in Lod Score Analysis

Sequential tests for the detection of linkage.

1955 • 1,590 citations

Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

1974 • 1,022 citations

The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity.

1983 • 124 citations

Gene dosage and susceptibility to insulin‐dependent diabetes

1980 • 117 citations

Segregation analysis incorporating linkage markers. I. Single-locus models with an application to type I diabetes.

1984 • 109 citations

Some epistatic two-locus models of disease. II. The confounding of linkage and association.

1981 • 55 citations

Bias of the estimated recombination fraction and lod score due to an association between a disease gene a marker gene

1982 • 50 citations

Linkage analysis with misclassification at one locus

1977 • 48 citations

Epistasis effect: an alternative to the hypothesis of linkage disequilibrium in HLA associated diseases

1980 • 29 citations

Type I (insulin dependent) diabetes mellitus

1981 • 26 citations