Solubilization and partial purification of putative calcium channels labelled with [3H]-nimodipine

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

Calcium channel modulation by neurotransmitters, enzymes and drugs

1983 • 1,267 citations

Calcium Channel

1981 • 1,184 citations

Radiolabeling of proteins by reductive alkylation with [14C]formaldehyde and sodium cyanoborohydride

1978 • 317 citations

New Perspectives on Calcium Antagonists

1982 • 310 citations

Calcium channels: direct identification with radioligand binding studies

1982 • 302 citations

[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists.

1982 • 265 citations

The binding of [3H]nitrendipine to receptors for calcium channel antagonists in the heart, cerebral cortex, and ileum of rats

1982 • 227 citations

Purification of the saxitoxin receptor of the sodium channel from rat brain.

1981 • 223 citations

Membrane potential-dependent binding of scorpion toxin to the action potential Na+ ionophore. Studies with a toxin derivative prepared by lactoperoxidase-catalyzed iodination

1977 • 221 citations

Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes.

1979 • 214 citations

Maitotoxin, a Ca2+ channel activator candidate.

1982 • 198 citations

Calcium antagonists receptor sites labeled with [3H]nitrendipine

1982 • 193 citations

Sodium Uptake Associated with Activation of Action Potential Ionophores of Cultured Neuroblastoma and Muscle Cells

1973 • 188 citations

The saxitoxin receptor of the sodium channel from rat brain. Evidence for two nonidentical beta subunits.

1982 • 163 citations

Evidence for multiple receptor sites within the putative calcium channel

1982 • 134 citations

Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel.

1980 • 129 citations

[3H]-Nitrendipine, a potent calcium antagonist, binds with high affinity to cardiac membranes.

1981 • 129 citations

Calcium antagonists High-affinity binding and inhibition of calcium transport in a clonal cell line.

1982 • 125 citations

Calcium ionic channels in electrically excitable membrane

1980 • 112 citations

Identification of putative calcium channels in skeletal muscle microsomes

1982 • 102 citations

Purification of the putative calcium channel from skeletal muscle with the aid of [3H]-nimodipine binding

1983 • 98 citations

The Action of Cardiotoxins on Cardiac Plasma Membranes

1982 • 87 citations

Molecular Size of the Tetrodotoxin Binding Site estimated by Irradiation Inactivation

1973 • 85 citations

Lipid-soluble toxins thought to be specific for Na+ channels block Ca2+ channels in neuronal cells

1982 • 75 citations

Characterization of [3H]nifedipine binding sites in rabbit myocardium

1982 • 75 citations

Calcium and potassium currents in muscle fibres of an insect (Carausius morosus).

1982 • 74 citations

Binding of [3H]nimodipine to cardiac and smooth muscle membranes

1982 • 68 citations

A cardiac tetrodotoxin-binding component: biochemical identification, characterization, and properties

1981 • 52 citations

Reconstitution of the voltage-sensitive sodium channel of rat brain from solubilized components.

1981 • 44 citations

[3H]-Nimodipine and [3H]-nitrendipine as tools to directly identify the sites of action of 1,4-dihydropyridine calcium antagonists in guinea-pig tissues. Tissue-specific effects of anions and ionic strength.

1982 • 42 citations

[3H]nitrendipine labelling of the Ca2+ channel in skeletal muscle

1982 • 41 citations

Glycoprotein characteristics of the sodium channel saxitoxin-binding component from mammalian sarcolemma

1981 • 34 citations

Solubilization of a mammalian ?-adrenergic receptor

1978 • 23 citations

Mammalian β-adrenoceptors: concomitant biospecific elution with protein kinase activity from sepharose-alprenolol

1981 • 5 citations