Molecular cloning of the rat analogue of human CD59: structural comparison with human CD59 and identification of a putative active site

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

‘Touchdown’ PCR to circumvent spurious priming during gene amplification

1991 • 2,630 citations

Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering

1990 • 750 citations

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

1989 • 640 citations

Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.

1989 • 407 citations

Membrane proteins that protect against complement lysis

1994 • 270 citations

Isolation from Human Erythrocytes of a New Membrane Protein Which Inhibits the Formation of Complement Transmembrane Channels1

1988 • 266 citations

Phosphatidylinositol glycan (PI-G) anchored membrane proteins. Amino acid requirements adjacent to the site of cleavage and PI-G attachment in the COOH-terminal signal peptide.

1992 • 211 citations

Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9.

1991 • 206 citations

A novel membrane glycoprotein capable of inhibiting membrane attack by homologous complement

1989 • 203 citations

Structure of a soluble, glycosylated form of the human complement regulatory protein CD59

1994 • 175 citations

Monoclonal antibodies capable of causing hemolysis of neuraminidase-treated human erythrocytes by homologous complement.

1989 • 128 citations

The Rat Clofibrate-InducibleCYP4AGene Subfamily I. Complete Intron and Exon Sequence of theCYP4A1andCYP4A2Genes, Unique Exon Organization, and Identification of a Conserved 19-bp Upstream Element

1989 • 122 citations

Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins.

1993 • 114 citations

Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59

1992 • 108 citations

Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement

1992 • 87 citations

Complement-inhibiting activities of human CD59 and analogues from rat, sheep, and pig are not homologously restricted.

1994 • 87 citations

Tissue distribution of complement regulatory membrane proteins in rats.

1994 • 74 citations

Contribution of the N-linked carbohydrate of erythrocyte antigen CD59 to its complement-inhibitory activity.

1992 • 67 citations

Determination of Carboxyl-Terminal Residue and Bisulfide Bonds of MACIF (CD59), a Glycosyl-Phosphatidylinositol-Anchored Membrane Protein1

1993 • 66 citations

Role of CD59 in experimental glomerulonephritis in rats

1994 • 53 citations

Killing of rat glial cells by complement: Deficiency of the rat analogue of CD59 is the cause of oligodendrocyte susceptibility to lysis

1993 • 53 citations

Characterization of promoter elements of an interferon-inducible Ly-6E/A differentiation antigen, which is expressed on activated T cells and hematopoietic stem cells.

1990 • 51 citations

Cis- and trans-acting elements required for constitutive and cytokine-regulated expression of the mouse complement C3 gene

1992 • 40 citations

Colocalization of the Human CD59 Gene to 11p13 with the MIC11 Cell Surface Antigen

1993 • 36 citations

The sheep analogue of human CD59: purification and characterization of its complement inhibitory activity.

1993 • 33 citations

Sequence‐specific

1993 • 32 citations

Isolation and Expression of the Full-Length cDNA Encoding CD59 Antigen of Human Lymphocytes

1990 • 30 citations

Gene for human CD59 (likely Ly-6 homologue) is located on the short arm of chromosome 11

1989 • 30 citations

Quantitative electroelution of oligonucleotides and large DNA fragments from gels and purification by electrodialysis

1987 • 24 citations

Elements of the rat tropoelastin gene associated with alternative splicing

1992 • 22 citations

Characterization Of Promoter Elements Of An Interferon-Inducible Ly-6E/A Differentiation Antigen, Which Is Expressed On Activated T Cells And Hematopoietic Stem Cells

1990 • 15 citations

Immunolocalization and characterization of the rat analogue of human CD59 in kidney and glomerular cells.

1993 • 14 citations

Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line.

1994 • 10 citations

Three types of rat U1 small nuclear RNA genes with different flanking sequences are induced to express in vivo

1988 • 9 citations