Contribution of the N-linked carbohydrate of erythrocyte antigen CD59 to its complement-inhibitory activity.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

1989 • 640 citations

The carbohydrate-binding specificity of pea and lentil lectins. Fucose is an important determinant.

1981 • 568 citations

Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.

1990 • 529 citations

Selective radioactive labeling of cell surface sialoglycoproteins by periodate-tritiated borohydride.

1977 • 511 citations

Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.

1989 • 407 citations

The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9.

1990 • 403 citations

Isolation from Human Erythrocytes of a New Membrane Protein Which Inhibits the Formation of Complement Transmembrane Channels1

1988 • 266 citations

Site specificity of the chorionic gonadotropin N-linked oligosaccharides in signal transduction

1989 • 225 citations

Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9.

1991 • 206 citations

A novel membrane glycoprotein capable of inhibiting membrane attack by homologous complement

1989 • 203 citations

The Thy-1 antigen exhibits rapid lateral diffusion in the plasma membrane of rodent lymphoid cells and fibroblasts.

1987 • 161 citations

Role of sugar chains in the in vitro biological activity of human erythropoietin produced in recombinant Chinese hamster ovary cells.

1990 • 140 citations

Monoclonal antibodies capable of causing hemolysis of neuraminidase-treated human erythrocytes by homologous complement.

1989 • 128 citations

High lateral mobility of endogenous and transfected alkaline phosphatase: a phosphatidylinositol-anchored membrane protein.

1987 • 124 citations

20 KDa homologous restriction factor of complement resembles T cell activating protein

1989 • 119 citations

In vitro expression and site-specific mutagenesis of the cloned human lipoprotein lipase gene. Potential N-linked glycosylation site asparagine 43 is important for both enzyme activity and secretion.

1990 • 103 citations

Regulatory control of complement on blood platelets

1989 • 101 citations

Effect of complement proteins C5b-9 on blood platelets. Evidence for reversible depolarization of membrane potential.

1985 • 90 citations

Rapid lateral diffusion of the variant surface glycoprotein in the coat of Trypanosoma brucei

1988 • 73 citations

Regulatory control of the terminal complement proteins at the surface of human endothelial cells: neutralization of a C5b-9 inhibitor by antibody to CD59

1990 • 72 citations

Amplified gene expression in CD59-transfected Chinese hamster ovary cells confers protection against the membrane attack complex of human complement

1991 • 63 citations

The CD59 antigen is a structural homologue of murine Ly‐6 antigens but lacks interferon inducibility

1990 • 54 citations

Prevention of complement activation on the homologous cell membrane of nucleated cells as well as erythrocytes

1983 • 52 citations

Purification of 1F5 antigen that prevents complement attack on homologous cell membranes.

1990 • 51 citations

Amino-Terminal Amino Acid Sequence and Chemical and Functional Properties of a Membrane Attack Complex-Inhibitory Factor from Human Erythrocyte Membranes1

1989 • 48 citations

Effect of Modification of N-Acetylneuraminic Acid on the Biological Activity of Human and Ovine Follicle-stimulating Hormone

1971 • 29 citations

COMPLEMENT IN INFLAMMATION

2004 • 24 citations