Validation of Methods for Oropharyngeal Cancer HPV Status Determination in US Cooperative Group Trials

Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

2010 • 5,874 citations

Improved Survival of Patients With Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma in a Prospective Clinical Trial

2008 • 2,660 citations

Distinct Risk Factor Profiles for Human Papillomavirus Type 16–Positive and Human Papillomavirus Type 16–Negative Head and Neck Cancers

2008 • 1,492 citations

Overexpression of p16INK4A as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri

2001 • 1,025 citations

Molecular Classification Identifies a Subset of Human Papillomavirus–Associated Oropharyngeal Cancers With Favorable Prognosis

2006 • 794 citations

A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen

2007 • 726 citations

Prognostic Significance of p16^INK4A and Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial

2010 • 702 citations

Effect of HPV-Associated p16^INK4A Expression on Response to Radiotherapy and Survival in Squamous Cell Carcinoma of the Head and Neck

2009 • 605 citations

Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus‐associated head and neck cancer based on a prospective clinical experience

2010 • 461 citations

Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial

2011 • 456 citations

p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors

2011 • 441 citations

Head and Neck Cancers

2011 • 417 citations

p16 Positive Oropharyngeal Squamous Cell Carcinoma:An Entity With a Favorable Prognosis Regardless of Tumor HPV Status

2010 • 393 citations

Chemoselection As a Strategy for Organ Preservation in Advanced Oropharynx Cancer: Response and Survival Positively Associated With HPV16 Copy Number

2008 • 359 citations

p16INK4a immunostaining in cytological and histological specimens from the uterine cervix: A systematic review and meta-analysis

2009 • 313 citations

Comparative Prognostic Value of HPV16 E6 mRNA Compared With In Situ Hybridization for Human Oropharyngeal Squamous Carcinoma

2009 • 311 citations

Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas

2001 • 309 citations

Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor origin.

2003 • 298 citations

High-Risk Human Papillomavirus E6/E7 mRNA Detection by a Novel In Situ Hybridization Assay Strongly Correlates With p16 Expression and Patient Outcomes in Oropharyngeal Squamous Cell Carcinoma

2011 • 285 citations

Detection of Human Papillomavirus-16 in Fine-Needle Aspirates to Determine Tumor Origin in Patients with Metastatic Squamous Cell Carcinoma of the Head and Neck

2007 • 251 citations

p16/ki‐67 dual‐stain cytology in the triage of ASCUS and LSIL Papanicolaou cytology

2011 • 220 citations

A comparison of clinically utilized human papillomavirus detection methods in head and neck cancer

2011 • 187 citations

Evaluation of human papillomavirus testing for squamous cell carcinoma of the tonsil in clinical practice

2011 • 151 citations

Generation of type-specific probes for the detection of single-copy human papillomavirus by a novel in situ hybridization method.

1998 • 78 citations

Expression of p16 in benign and malignant cystic squamous lesions of the neck

2009 • 75 citations

Expression of p16 in non-small cell lung cancer and its prognostic significance: A meta-analysis of published literatures

2011 • 45 citations

p16INK4a/CDKN2 expression and its relationship with oral squamous cell carcinoma is our current knowledge enough?

2011 • 40 citations

The use of an immunohistochemical diagnostic panel to determine the primary site of cervical lymph node metastases of occult squamous cell carcinoma

2009 • 34 citations

Ancillary Studies in Determining Human Papillomavirus Status of Squamous Cell Carcinoma of the Oropharynx: A Review

2011 • 31 citations

Survey on human papillomavirus/p16 screening use in oropharyngeal carcinoma patients in the United States

2009 • 18 citations

Immunohistochemistry for p16, but not Rb or p21, is an independent predictor of prognosis in conservatively treated, clinically localised prostate cancer

2010 • 17 citations

A useful protocol for analyses of mutations of the epidermal growth factor receptor gene

2006 • 10 citations

Survey of the use of tests for human papilloma virus and epidermal growth factor receptor for squamous cell carcinoma of the head and neck in UK head and neck multidisciplinary teams

2011 • 8 citations