Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor origin.

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1993 • 3,680 citations

Cancer Statistics, 2001

2001 • 3,342 citations

Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

2000 • 3,004 citations

Overexpression of p16INK4A as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri

2001 • 1,025 citations

Human Papillomavirus Infection as a Risk Factor for Squamous-Cell Carcinoma of the Head and Neck

2001 • 931 citations

Genotyping of 27 Human Papillomavirus Types by Using L1 Consensus PCR Products by a Single-Hybridization, Reverse Line Blot Detection Method

1998 • 652 citations

High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma.

1996 • 587 citations

Expression Status of p16 Protein Is Associated with Human Papillomavirus Oncogenic Potential in Cervical and Genital Lesions

1998 • 584 citations

Expression of p16 Protein Identifies a Distinct Entity of Tonsillar Carcinomas Associated with Human Papillomavirus

2003 • 415 citations

Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control

2002 • 392 citations

Human papillomavirus (HPV) in head and neck cancer

1997 • 373 citations

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

1996 • 362 citations

Prevalence, distribution, and viral load of human papillomavirus 16 DNA in tonsillar carcinomas

2001 • 338 citations

A novel in situ hybridization signal amplification method based on the deposition of biotinylated tyramine.

1995 • 316 citations

Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas

2001 • 309 citations

Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control.

1998 • 279 citations

Determinants of Genital Human Papillomavirus Detection in a US Population

2001 • 259 citations

Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer

2002 • 236 citations

Detection of human papillomavirus DNA and oncoprotein overexpression are associated with distinct morphological patterns of tonsillar squamous cell carcinoma.

1998 • 221 citations

p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrepTM smears

2002 • 205 citations

p16INK4a Is a Useful Marker for the Diagnosis of Adenocarcinoma of the Cervix Uteri and Its Precursors

2003 • 183 citations

Unknown Primary Head and Neck Squamous Cell Carcinoma: Molecular Identification of the Site of Origin

1999 • 149 citations

Diagnosis of Nasopharyngeal Carcinoma by DNA Amplification of Tissue Obtained by Fine-Needle Aspiration

1992 • 143 citations

The Diagnostic Significance of a “Lump in the Neck”

1952 • 84 citations

An association of HPV 16 with squamous cell carcinoma of Waldeyer's tonsillar ring

1999 • 82 citations

Generation of type-specific probes for the detection of single-copy human papillomavirus by a novel in situ hybridization method.

1998 • 78 citations

Diagnosis and management of squamous cell carcinoma of unknown primary tumor site of the neck.

1993 • 75 citations

Epstein-Barr virus detection in neck metastases by in-situ hybridization in fine-needle aspiration cytologic studies: An aid for differentiating the primary site

2000 • 74 citations

Novel therapeutics for head and neck cancer

2002 • 59 citations

Role of epstein‐barr virus in fine‐needle aspirates of metastatic neck nodes in the diagnosis of nasopharyngeal carcinoma

1995 • 51 citations

HPV DNA Detection by In Situ Hybridization with Catalyzed Signal Amplification on Thin-layer Cervical Smears

2002 • 32 citations

Detection of Epstein-Barr Virus in Metastatic Lymph Nodes of Patients With Nasopharyngeal Carcinoma and a Primary Unknown Carcinoma

2003 • 25 citations

Detection of Epstein-Barr virus-associated antigen in fine needle aspiration smears from cervical lymph nodes in the diagnosis of nasopharyngeal carcinoma.

1989 • 16 citations

HPV in Oropharyngeal Cancers: New Data Inspire Hope for Vaccines

2000 • 13 citations

Onkogene humane Papillomaviren

1999 • 13 citations

Colourimetric signal amplification of in situ hybridization assay for human papillomavirus DNA detection in cytological samples.

2002 • 4 citations