Anti-self HLA may be clonally expressed.

The clonal selection theory of acquired immunity

1959 • 2,008 citations

The somatic generation of immune recognition

1971 • 974 citations

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis

1974 • 832 citations

H-2 compatability requirement for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus. Different cytotoxic T-cell specificities are associated with structures coded for in H-2K or H-2D;.

1975 • 623 citations

The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens.

1975 • 479 citations

H-2 compatibility is required for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus.

1975 • 366 citations

Y-antigen killing by T cells of women is restricted by HLA

1977 • 326 citations

HLA restriction of cell-mediated lysis of influenza virus-infected human cells

1977 • 274 citations

Cytotoxic T cells learn specificity for self H–2 during differentiation in the thymus

1978 • 219 citations

Two Different V_H Gene Products Make Up the T‐Cell Receptors

1976 • 179 citations

Functional interactions of viral and histocompatibility antigens at tumor cell surfaces.

1975 • 165 citations

CELLS MEDIATING SPECIFIC IN VITRO CYTOTOXICITY

1971 • 157 citations

Human cell-mediated cytotoxicity against modified target cells is restricted by HLA

1977 • 103 citations

Cytotoxic T-cell responses to H-Y: mapping of the Ir genes.

1978 • 83 citations

THE IMPORTANCE OF H-Y INCOMPATIBILITY IN HUMAN ORGAN TRANSPLANTATION

1978 • 56 citations

Further in vitro evidence for polyvalent specificity of immune lymphocytes.

1970 • 39 citations

Cross‐Reactivity between the First and Second Segregant Series of the HLA System

1976 • 19 citations

An antibody cross-reacting with LA and FOUR antigens of theHL-A system

1974 • 15 citations

Specific elimination of cytotoxic cells

1977 • 7 citations

H–2 restriction, the thymus and the immune response

1978 • 6 citations