Transcript synthesis and surface expression of the interleukin-2 receptor (alpha-, beta-, and gamma-chain) by normal and malignant myeloid cells

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Cytokine signal transduction

1994 • 1,358 citations

Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans

1993 • 1,317 citations

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 Receptor

1993 • 1,128 citations

Cloning of the γ Chain of the Human IL-2 Receptor

1992 • 835 citations

The IL-2/IL-2 receptor system: A current overview

1993 • 778 citations

Sharing of the Interleukin-2 (IL-2) Receptor γ Chain Between Receptors for IL-2 and IL-4

1993 • 734 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

The IL-2 Receptor Complex: Its Structure, Function, and Target Genes

1993 • 601 citations

Prolongation of survival of human polymorphonuclear neutrophils by granulocyte-macrophage colony-stimulating factor is caused by inhibition of programmed cell death

1992 • 367 citations

The interleukin-2 receptor.

1991 • 354 citations

Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes.

1994 • 301 citations

Expression of interleukin 2 receptors and binding of interleukin 2 by gamma interferon-induced human leukemic and normal monocytic cells.

1985 • 288 citations

The Interleukin 2 Receptor

1989 • 244 citations

IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: Demonstration of a novel role for c-myc

1992 • 242 citations

Interleukin 2 receptor gamma chain expression on resting and activated lymphoid cells.

1994 • 129 citations

Interleukin‐2 prevention of apoptosis in human neutrophils

1994 • 117 citations

Expression and role of p75 interleukin 2 receptor on human monocytes.

1990 • 111 citations

Functional interleukin-2 receptors on intestinal epithelial cells.

1993 • 100 citations

Receptors for interleukin 2 on human squamous cell carcinoma cell lines and tumor in situ.

1992 • 80 citations

Functional consequences of monocyte IL-2 receptor expression. Induction of IL-1 beta secretion by IFN gamma and IL-2.

1989 • 77 citations

Expression of interleukin-2 receptor beta subunit in hematopoietic malignancies

1989 • 72 citations

Expression of interleukin-2 receptor beta subunit in hematopoietic malignancies

1989 • 64 citations

Clonal analysis of bcr-abl rearrangement in T lymphocytes from patients with chronic myelogenous leukemia

1992 • 53 citations

Granulocyte-macrophage colony-stimulating factor and interleukin-3 induce surface expression of interleukin-2 receptor p55-chain and CD4 by human eosinophils.

1990 • 50 citations

Expression of the interleukin-2 receptor on human fibroblasts and its biological significance

1992 • 49 citations

Expression of interleukin-2 receptor gamma chain on human neutrophils

1994 • 46 citations

Flow cytometric analysis of expression of interleukin-2 receptor beta chain (p70-75) on various leukemic cells

1990 • 35 citations

The IL-2 receptor alpha-chain alters the binding of IL-2 to the beta-chain.

1991 • 32 citations

The IL-2 receptor present on human embryonic fibroblasts is functional in the absence of P64/IL-2R_γ chain

1993 • 25 citations

Transcriptional activation of the macrophage colony-stimulating factor gene by IL-2 is associated with secretion of bioactive macrophage colony-stimulating factor protein by monocytes and involves activation of the transcription factor NF-kappa B.

1993 • 24 citations

Activation of NF-kappa B by interleukin 2 in human blood monocytes.

1992 • 14 citations

Alpha (p55) and beta (p75) chains of the interleukin-2 receptor are expressed by AML blasts.

1993 • 14 citations

Functional expression of interleukin 2 receptor in a human factor-dependent megakaryoblastic leukemia cell line: evidence that granulocyte-macrophage colony-stimulating factor inhibits interleukin 2 binding to its receptor.

1993 • 13 citations

Differential expression of CD25 and HC2 antigens on subtypes of acute myeloid leukemias

1989 • 12 citations