The Intracellular Serpin Proteinase Inhibitor 6 Is Expressed in Monocytes and Granulocytes and Is a Potent Inhibitor of the Azurophilic Granule Protease, Cathepsin G

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

A Laboratory manual

1989 • 6,833 citations

Granules of the Human Neutrophilic Polymorphonuclear Leukocyte

1997 • 1,444 citations

The Electrophoretic α;₁-Globulin Pattern of Serum in α;₁-Antitrypsin Deficiency

1963 • 1,400 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

Maspin, a Serpin with Tumor-Suppressing Activity in Human Mammary Epithelial Cells

1994 • 913 citations

The serpin superfamily of proteinase inhibitors: structure, function, and regulation.

1994 • 879 citations

Prevention of Vertebrate Neuronal Death by the crmA Gene

1994 • 618 citations

Elastolytic Activity in Pulmonary Lavage Fluid from Patients with Adult Respiratory-Distress Syndrome

1981 • 528 citations

Elastase in Tissue Injury

1985 • 512 citations

Degradation of fibronectin by human leukocyte elastase. Release of biologically active fragments.

1980 • 386 citations

Proteolytic enzymes; a practical approach

1990 • 364 citations

A Cytosolic Granzyme B Inhibitor Related to the Viral Apoptotic Regulator Cytokine Response Modifier A Is Present in Cytotoxic Lymphocytes

1996 • 301 citations

Photo-Oxidative Disruption of Lysosomal Membranes Causes Apoptosis of Cultured Human Fibroblasts

1997 • 282 citations

Degradation of type IV (basement membrane) collagen by a proteinase isolated from human polymorphonuclear leukocyte granules.

1980 • 279 citations

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

1995 • 267 citations

Identification of Human Neutrophil-derived Cathepsin G and Azurocidin/CAP37 as Chemoattractants for Mononuclear Cells and Neutrophils

1997 • 264 citations

Interleukin‐8 processing by neutrophil elastase, cathepsin G and proteinase‐3

1994 • 238 citations

The ovalbumin family of serpin proteins

1993 • 221 citations

Squamous Cell Carcinoma Antigen 2 Is a Novel Serpin That Inhibits the Chymotrypsin-like Proteinases Cathepsin G and Mast Cell Chymase

1997 • 212 citations

Squamous cell carcinoma antigen is a new member of the serine protease inhibitors

1991 • 209 citations

Antimicrobial polypeptides of human neutrophils

1990 • 188 citations

Biochemical and pathologic evidence for proteolytic destruction of lung connective tissue in cystic fibrosis.

1985 • 172 citations

Antibiotic proteins of human neutrophils.

1990 • 159 citations

Antimicrobial polypeptides of human neutrophils

1990 • 152 citations

Elastase and Elastase-Inhibitor

1949 • 152 citations

The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities.

1996 • 140 citations

Human neutrophil elastase functions as a type III collagen “Collagenase”

1980 • 137 citations

Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity

1997 • 134 citations

Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases--a model of joint injury. I. Penetration of enzyme into rabbit articular cartilage and release of 35SO4-labeled material from the tissue.

1976 • 127 citations

Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor.

1992 • 127 citations

Structure of the Gene for Human Plasminogen Activator Inhibitor-2

1989 • 99 citations

Platelet activation by fMLP-stimulated polymorphonuclear leukocytes: the activity of cathepsin G is not prevented by antiproteinases

1991 • 97 citations

Biosynthesis and Processing of Proteinase 3 in U937 Cells

1996 • 79 citations

Molecular Cloning, Expression, and Partial Characterization of Two Novel Members of the Ovalbumin Family of Serine Proteinase Inhibitors

1995 • 79 citations

Serine Proteinases of Mast Cell and Leukocyte Granules: A League of Their Own

1994 • 78 citations

Specificity of human cathepsin G

1998 • 76 citations

Cloning and molecular characterization of a human intracellular serine proteinase inhibitor.

1993 • 72 citations

Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils.

1989 • 71 citations

Kinetic Mechanism of the Inhibition of Cathepsin G by α₁-Antichymotrypsin and α₁-Proteinase Inhibitor

1998 • 57 citations

The Contribution of the Conserved Hinge Region Residues of .alpha.1-Antitrypsin to Its Reaction with Elastase

1995 • 56 citations

Proteinase Inhibitor 6 Cannot Be Secreted, Which Suggests It Is a New Type of Cellular Serpin

1996 • 54 citations

Molecular Cloning of Bomapin (Protease Inhibitor 10), a Novel Human Serpin That Is Expressed Specifically in the Bone Marrow

1995 • 51 citations

Biology and Facultative Secretion of Plasminogen Activator Inhibitor-2

1993 • 50 citations

Production and characterization of recombinant human proteinase inhibitor 6 expressed in Pichia pastoris

1995 • 44 citations

Gene Structure, Chromosomal Localization, and Expression of the Murine Homologue of Human Proteinase Inhibitor 6 (PI-6) Suggests Divergence of PI-6 from the Ovalbumin Serpins

1995 • 42 citations

Identification and purification of a novel serine proteinase inhibitor

1993 • 39 citations

Neutral proteinase expression by human mononuclear phagocytes: a prominent role of cellular differentiation.

1992 • 36 citations

Inhibitory properties of recombinant human monocyte/neutrophil elastase inhibitor.

1995 • 35 citations

Complementary DNA Cloning and Kinetic Characterization of a Novel Intracellular Serine Proteinase Inhibitor: Mechanism of Action with Trypsin and Factor Xa as Model Proteinases

1994 • 26 citations

Human Cytoplasmic Antiproteinase Neutralizes Rapidly and Efficiently Chymotrypsin and Trypsin-like Proteases Utilizing Distinct Reactive Site Residues

1996 • 25 citations

Proteinase Inhibitor 6 (PI-6) Expression in Human Skin: Induction of PI-6 and a PI-6/Proteinase Complex during Keratinocyte Differentiation

1998 • 21 citations

Purification, cDNA Cloning, and Characterization of a New Serpin with Megakaryocyte Maturation Activity

1997 • 16 citations

5 The Natural Anticoagulants

1986 • 15 citations

Tissue factor and plasminogen activator inhibitor expression in the differentiation of myeloid leukemic cells.

1993 • 10 citations