ABT-627, a potent endothelin receptor A antagonist, inhibits ovarian carcinoma growth in vitro

Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth.

1999 • 205 citations

Role of Endothelin-1 in Neovascularization of Ovarian Carcinoma

2000 • 188 citations

Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells.

2000 • 127 citations

Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells.

1997 • 120 citations

Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells.

1995 • 105 citations

Pharmacokinetics and pharmacodynamic effects of ABT‐627, an oral ETA selective endothelin antagonist, in humans

2000 • 49 citations

Endothelin-1 promotes proteolytic activity of ovarian carcinoma

2002 • 40 citations

‘Irreversible’ Endothelin-1 Binding Does Not Prohibit ABT-627 From Reversing Endothelin-1-Induced Effects

2000 • 12 citations