Accelerated reconstitution of platelets and erythrocytes after syngeneic transplantation of bone marrow cells derived from thrombopoietin pretreated donor mice

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

1994 • 1,328 citations

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

1994 • 1,138 citations

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

1994 • 1,081 citations

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI

1994 • 987 citations

Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.

1992 • 525 citations

The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production.

1994 • 443 citations

Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis

1993 • 359 citations

Regulation of megakaryocytopoiesis

1989 • 305 citations

The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets

1995 • 286 citations

Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy.

1995 • 269 citations

Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.

1993 • 174 citations

Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth.

1993 • 134 citations

Growth factors affecting human thrombocytopoiesis: potential agents for the treatment of thrombocytopenia [editorial]

1992 • 131 citations

Megakaryocytopoiesis and platelet production: a review.

1987 • 114 citations

The structure, biology and potential therapeutic applications of recombinant thrombopoietin

1994 • 77 citations

Sustained engraftment of mice transplanted with IL-1-primed blood-derived stem cells.

1992 • 70 citations

Regulation of megakaryocytopoiesis

1989 • 35 citations

Continuous infusion of interleukin-6 in sublethally irradiated mice accelerates platelet reconstitution and the recovery of myeloid but not of megakaryocytic progenitor cells in bone marrow.

1993 • 22 citations

Megakaryocyte Colony-Stimulating Factor and Thrombopoiesis

1989 • 16 citations

Mechanism of the development of thrombocytosis due to bleeding

1957 • 15 citations