Transcription signals in embryonic Xenopus laevis U1 RNA genes.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Lambdoid phages that simplify the recovery of in vitro recombinants

1977 • 779 citations

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

1983 • 593 citations

SnRNAs, SnRNPs, and RNA Processing

1982 • 458 citations

Transcription of a gene for human U1 small nuclear RNA

1982 • 175 citations

Chemical and enzymatic synthesis of gene fragments

1983 • 174 citations

True genes for human U1 small nuclear RNA. Copy number, polymorphism, and methylation.

1984 • 154 citations

Synthesis of human U1 RNA. II. Identification of two regions of the promoter essential for transcription initiation at position +1.

1984 • 148 citations

Purification of snRNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1)RNP antisera.

1983 • 143 citations

Human U1 Loci: Genes for human U1 RNA have dramatically similar genomic environments

1982 • 140 citations

Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5′ and 3′ flanking homology with other RNA polymerase II transcribed genes.

1983 • 135 citations

Differential expression of multiple U1 small nuclear RNAs in oocytes and embryos of Xenopus laevis

1984 • 131 citations

Abundant pseudogenes for small nuclear RNAs are dispersed in the human genome.

1981 • 123 citations

The RNA lariat: A new ring to the splicing of mRNA precursors

1984 • 113 citations

Purification of specific adenovirus 2 RNAs by preparative hybridization and selective thermal elution

1979 • 89 citations

Xenopus laevis U1 snRNA genes: characterisation of transcriptionally active genes reveals major and minor repeated gene families.

1984 • 84 citations

Cloning of nematode tRNA genes and their expression in the frog oocyte.

1978 • 76 citations

The Two Embryonic U1 Small Nuclear RNAs of Xenopus laevis Are Encoded by a Major Family of Tandemly Repeated Genes

1984 • 39 citations

Loci for human U1 RNA: Structural and evolutionary implications

1983 • 28 citations

Characterization of Three Chicken Pseudogenes for U1 RNA

1984 • 8 citations