Role of hormones and growth factors in melanomas.

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

1987 • 895 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1984 • 666 citations

The platelet-derived growth factor

1978 • 649 citations

Melatonin: A Coordinating Signal for Mammalian Reproduction?

1985 • 631 citations

Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor

1983 • 520 citations

Purification of the fibroblast growth factor activity from bovine brain.

1978 • 498 citations

Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus.

1987 • 448 citations

Structure of a Mouse Submaxillary Messenger RNA Encoding Epidermal Growth Factor and Seven Related Proteins

1983 • 448 citations

Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts

1975 • 432 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product

1985 • 368 citations

Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.

1988 • 357 citations

Characterization of estrogen responsive transforming activity in human breast cancer cell lines.

1986 • 330 citations

Human melanoma-associated antigen p97 is structurally and functionally related to transferrin

1982 • 288 citations

Estrogen-Induced Factors of Breast Cancer Cells Partially Replace Estrogen to Promote Tumor Growth

1986 • 273 citations

bFGF is the putative natural growth factor for human melanocytes

1987 • 259 citations

The molecular biology of platelet-derived growth factor

1983 • 252 citations

Both normal and tumor cells produce basic fibroblast growth factor

1986 • 250 citations

Biology of tumor progression in human melanocytes.

1987 • 236 citations

Melanoma, Growth Factors, Acanthosis Nigricans, the Sign of Leser-Trélat, and Multiple Acrochordons

1987 • 235 citations

The prognosis for malignant melanoma in the pregnant woman

1951 • 233 citations

ŒSTROGEN RECEPTORS IN HUMAN MALIGNANT MELANOMA

1976 • 220 citations

Factors Regulating Growth And Pigmentation Of Melanoma Cells

1976 • 219 citations

Epidermal Growth Factor

1972 • 214 citations

Expression of epidermal growth factor receptor in human cultured cells and tissues: relationship to cell lineage and stage of differentiation.

1986 • 214 citations

Inhibition of tumour growth in vivo and in vitro by prostaglandin E

1976 • 196 citations

Platelet thrombospondin mediates attachment and spreading of human melanoma cells.

1987 • 196 citations

Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma

1985 • 190 citations

Laminin increases the release of type IV collagenase from malignant cells.

1986 • 188 citations

Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor.

1986 • 187 citations

Adverse effect of pregnancy on melanoma. A reappraisal

1976 • 175 citations

Melanoma growth stimulatory activity: Isolation from human melanoma tumors and characterization of tissue distribution

1988 • 169 citations

Estrogen Regulation of Epidermal Growth Factor Receptor Messenger Ribonucleic Acid

1988 • 168 citations

Malignant melanoma and pregnancy

1985 • 168 citations

Control of Phenotypic Expresssion of Cultured Melanoma Cells by Melanocyte Stimulating Hormones

1973 • 160 citations

Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors

1987 • 145 citations

Biological effect of epidermal growth factor on the in vitro growth of human tumors.

1987 • 134 citations

Melanoma with pregnancy.A report of 115 cases

1960 • 132 citations

Purification of melanoma growth stimulatory activity

1986 • 130 citations

The use of hormone-supplemented serum-free media in primary cultures

1979 • 130 citations

Malignant melanoma: Influence of site of lesion and age of patient in the female superiority in survival

1980 • 127 citations

Histologic features of tumors and the female superiority in survival from malignant melanoma

1980 • 118 citations

Cutaneous Melanoma in Relation to Exogenous Hormones and Reproductive Factors<xref ref-type="fn" rid="FN2">2</xref>

1983 • 111 citations

Prostaglandin E2 and D2 but Not MSH Stimulate the Proliferation of Pigment Cells in the Pinnal Epidermis of the DBA/2 Mouse

1986 • 111 citations

Purification of the receptor for nerve growth factor from A875 melanoma cells by affinity chromatography.

1983 • 104 citations

Characterization of autostimulatory and transforming growth factors from human melanoma cells.

1985 • 99 citations

Cell cycle effects of prostaglandins A1, A2, and D2 in human and murine melanoma cells in culture.

1986 • 99 citations

Cutaneous malignant melanoma in women: exogenous sex hormones and reproductive factors

1984 • 99 citations

Growth Regulation of Human Melanocytes: Mitogenic Factors in Extracts of Melanoma, Astrocytoma, and Fibroblast Cell Lines

1985 • 95 citations

The stimulation of normal human melanocyte proliferation in vitro by melanocyte growth factor from bovine brain

1985 • 94 citations

MALIGNANT MELANOMA: AN ANDROGEN-DEPENDENT TUMOUR?

1980 • 89 citations

Steroid Hormone Receptors and Melanoma

1980 • 89 citations

PREVIOUS PREGNANCY AS A PROTECTIVE FACTOR AGAINST DEATH FROM MELANOMA

1977 • 82 citations

The role of RNA and protein synthesis in mediating the action of MSH on mouse melanoma cells

1979 • 81 citations

Growth Factor and Cytogenetic Abnormalities in Cultured Nevi and Malignant Melanomas

1986 • 78 citations

In vitro modulation of proliferation and melanization of S91 melanoma cells by prostaglandins.

1987 • 76 citations

Extraction of a melanoma growth-stimulatory activity from culture medium conditioned by the Hs0294 human melanoma cell line.

1983 • 73 citations

Estrogen receptor in malignant melanoma.

1987 • 70 citations

Inhibition of human melanoma growth by prostaglandin A, D, and J analogues.

1986 • 69 citations

Influence of pineal gland on the growth and spread of melanoma in the hamster.

1967 • 68 citations

Effects of α-MSH on Melanogenesis and Tyrosinase of B-16 Melanoma

1972 • 68 citations

Incidence of Estrogen Receptor in Benign Nevi and Human Malignant Melanoma

1980 • 67 citations

A melanocyte-specific complementary DNA clone whose expression is inducible by melanotropin and isobutylmethyl xanthine.

1987 • 63 citations

Melanoma cells which require cyclic AMP for growth

1975 • 62 citations

Reversal by melatonin of the effect of pinealectomy on tumor growth.

1973 • 57 citations

Experimental metastasis correlates with cyclic AMP accumulation in B16 melanoma clones

1984 • 56 citations

THE GROWTH AND SPREAD OF WALKER 256 CARCINOMA IN PINEALECTOMIZED RATS.

1963 • 56 citations

Characterization of growth factors in human ovarian carcinomas.

1986 • 54 citations

Studies on Pigmentation of Endocrine Origin1

1945 • 52 citations

Epidermal Growth Factors

1978 • 51 citations

Estrogen and progesterone receptors and tamoxifen in malignant melanoma.

1980 • 51 citations

Regulation of cell shape in the Cloudman melanoma cell line.

1987 • 50 citations

Regulation of adenylate cyclase by β-melanotropin in the M2R melanoma cell line

1986 • 50 citations

Inhibition of human malignant melanoma colony-forming cells in vitro by prostaglandin A1.

1983 • 49 citations

Basic Science Review: Growth Factors in Cancer and Their Relationship to Oncogenes

1986 • 49 citations

Effect of pregnancy upon malignant melanoma.

1983 • 48 citations

Inhibition of B-16 melanoma growth by prostaglandin D2

1983 • 48 citations

Nerve growth factor—Recent developments and perspectives

1976 • 48 citations

Glucocorticoid receptors and the effect of glucocorticoids on the growth of B16 melanoma.

1981 • 46 citations

Purification and biological properties of type beta transforming growth factor from mouse transformed cells.

1986 • 45 citations

Effect of 17 beta-estradiol on the growth of estrogen receptor-positive human melanoma in vitro and in athymic mice.

1988 • 45 citations

Endocrine Factors and the Growth and Spread of 816 Melanoma2

1976 • 44 citations

Inability of anti-epidermal growth factor receptor monoclonal antibody to block “autocrine” growth stimulation in transforming growth factor-secreting melanoma cells.

1984 • 44 citations

Effect of melatonin on B16 melanoma growth in athymic mice.

1985 • 43 citations

Polypeptide growth factors: Some structural and mechanistic considerations

1980 • 42 citations

Photoperiodic Control of Melanoma Growth in Hamsters: Influence of Pinealectomy and Melatonin*

1983 • 38 citations

Inhibition by Melittin and Fluphenazine of Melanotropin Receptor Function and Adenylate Cyclase in M2R Melanoma Cell Membranes*

1987 • 37 citations

Prostaglandin Analogs as Inhibitors of Tumor Cell DNA Synthesis

1981 • 37 citations

Phosphorylated isomers of L-dopa stimulate MSH binding capacity and responsiveness to MSH in cultured melanoma cells

1987 • 36 citations

In vitro growth inhibition of human malignant melanoma cells by glucocorticoids.

1983 • 35 citations

A Diffusible Factor Restoring Contact Inhibition of Growth to Malignant Melanocytes

1974 • 35 citations

Sex related survival differences in instances of melanoma.

1984 • 34 citations

Dexamethasone, Prostaglandin A, and Retinoic Acid Modulation of Murine and Human Melanoma Cells Grown in Soft Agar<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 34 citations

Prostaglandin A1 and E1 inhibit the plating efficiency and proliferation of murine melanoma cells (Cloudman S-91) in soft agar

1982 • 33 citations

Actions of melanotropins on mouse melanoma cell growth in vitro.

1986 • 32 citations

Melanoma with pregnancy

1961 • 31 citations

Preparation of a monoclonal antibody to a melanoma growth‐stimulatory activity released into serum‐free culture medium by Hs0294 malignant melanoma cells

1987 • 31 citations

High Incidence and Characterization of Glucocorticoid Receptors in Human Malignant Melanoma<xref ref-type="fn" rid="fn2">2</xref>,<xref ref-type="fn" rid="fn3">3</xref>

1981 • 31 citations

Oestrogen and androgen receptors in melanoma

1980 • 31 citations

Glucocorticoid receptors and cell cycle progression in human melanoma cell lines

1985 • 29 citations

Role of pinealectomy on Walker 256 carcinoma in rats

1970 • 28 citations

Receptors for steroid hormones in human melanoma.

1976 • 26 citations

Growth inhibition by glucocorticoids in RPMI 3460 melanoma cells.

1981 • 25 citations

Phase II study of high-dose tamoxifen (NSC-180973) in patients with disseminated malignant melanoma

1982 • 25 citations

Growth-inhibiting effect of crude pineal extracts on human melanoma cellsin vitro is different from that of known synthetic pineal substances

1987 • 24 citations

Endocrine correlates of human malignant melanoma

1979 • 24 citations

Receptor for glucocorticoids in RPMI 3460 melanoma cells.

1980 • 24 citations

Sex factors in growth of malignant melanoma in hamsters: in vivo and in vitro correlation.

1970 • 23 citations

Hormonal Influences on Growth of B16 Murine Melanoma<xref ref-type="fn" rid="FN2">2</xref>

1985 • 23 citations

MALIGNANT MELANOMA OF THE CHOROID WITH EXTENSIVE METASTASIS TREATED BY REMOVING SECRETING TISSUE OF THE TESTICLES

1943 • 22 citations

Inhibition of hamster melanoma growth by estrogen.

1987 • 22 citations

Alpha tocopheryl succinate inhibits melanocyte-stimulating hormone (MSH)-sensitive adenylate cyclase activity in melanoma cells

1987 • 22 citations

Dibutyryl cyclic AMP arrests the growth of cultivated cloudman melanoma cells in the late S and G2 phases of the cell cycle

1977 • 21 citations

Steroid hormone receptors in human melanoma

1981 • 21 citations

Endocrine treatment with anti-estrogen, anti-androgen or progestagen of advanced malignant melanoma: Three consecutive phase II trials

1985 • 20 citations

Neuroendocrine and endocrine correlates to hamster melanoma growth in vitro.

1978 • 20 citations

Growth stimulation of human melanocytes: Identification and characterization of melanoma-derived melanocyte growth factor (M-McGF)

1987 • 20 citations

Brief Communication: In Vitro Effects of Melanocyte-Stimulating Hormone, Adrenocorticotropic Hormone, 171β-Estradiol, or Testosterone Propionate on Cloudman S91 Mouse Melanoma Cells2

1974 • 19 citations

Oral Contraceptives and Malignant Melanoma

1968 • 19 citations

Steroid hormone receptor studies in melanoma model systems

1980 • 19 citations

Influence of Estrogen Administration on Tumor Characteristics and Survival in Women With Cutaneous Melanoma<xref ref-type="fn" rid="FN2">2</xref>

1985 • 17 citations

In vitro growth promotion in human malignant melanoma cells by fibroblast growth factor.

1982 • 17 citations

THE MALIGNANT MELANOMA OF HAMSTERS: III. EFFECTS OF SEX AND CASTRATION ON THE GROWTH OF THE TRANSPLANTED TUMOR*

1963 • 16 citations

Glucocorticoid Modulation of Adrenocorticotropin-Induced Melanogenesis in the Cloudman S-91 Melanoma <i>in vitro</i>

1978 • 15 citations

α-MSH-induced changes in protein phosphorylation of Cloudman S91 mouse melanoma cells

1987 • 15 citations

Modification of Pancreatic Carcinogenesis in the Hamster Model. XII. Dose-Related Effect of Ethanol<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 14 citations

Effects of estradiol on estrogen receptor, progesterone receptor, and tyrosinase in hamster melanoma transplanted into athymic mice.

1988 • 13 citations

Further Studies on Endocrine Factors and the Growth and Spread of B&lt;sub&gt;16&lt;/sub&gt; Melanoma

1981 • 12 citations

The effect of tamoxifen on the growth of human malignant melanoma in Vitro

1984 • 12 citations

Autocrine tumor growth regulation and tumor-associated hypoglycemia in murine melanoma B16 in vivo.

1986 • 12 citations

Glucocorticoids and melanoma: Receptor properties of dexamethasone sensitive and resistant tumors

1982 • 12 citations

Inhibition of Growth of B16 Melanoma by Glucocorticoids Does Not Result Directly from Receptor-Mediated Inhibition of Tumour Cells

1988 • 11 citations

Interaction of ACTH, corticosterone and cyclic nucleotides in harding-passey melanoma malanogenesis

1978 • 10 citations

Biological behavior of MM1 hamster melanoma.

1982 • 10 citations

Response of Cloudman S91 Melanoma Cells to Melanocyte-Stimulating Hormone: Enhancement by Cytochalasin B2

1976 • 9 citations

REMOVAL OF TESTES IN TREATMENT OF MELANOMA

1943 • 9 citations

Effect of triamcinolone acetonide on the growth of NEL-M1 human melanoma cells cultured in the presence and absence of growth stimulatory agents.

1986 • 9 citations

Suppression of DNA synthesis in NEL-M1 human melanoma cells by triamcinolone acetonide.

1985 • 8 citations

Phase II study of 6 -methylpregn-4-ene-3,11,20-trione (NSC-17256).

1971 • 8 citations

Immunoaffinity purification of melanoma growth stimulatory activity

1988 • 8 citations

Effect of adrenal manipulation on glucocorticoid receptors in MM1 hamster melanoma.

1982 • 7 citations

FEMINIZATION AND DEMASCULINIZATION OF A 17-YEAR-OLD GIRL BY INJECTIONS OF STILBESTROL

1940 • 7 citations

Glucocorticoid effect on melphalan cytotoxicity, cell-cycle position, cell size, and [3H]uridine incorporation in one of three human melanoma cell lines.

1987 • 6 citations

Contact Inhibitory Factor Also Restores Anchorage and Serum Dependence to Hamster Melanoma Cells

1986 • 4 citations

Effect of Medroxyprogesterone and an Aorta-Derived Cell Growth Inhibitor on B16 Melanoma in Mice&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1984 • 4 citations