Postnatal regulation of fibroblast growth factor ligand and receptor gene expression in rat thoracic aorta.

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

1992 • 760 citations

Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor.

1991 • 722 citations

Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.

1990 • 635 citations

Role of basic fibroblast growth factor in vascular lesion formation.

1991 • 521 citations

Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy.

1993 • 408 citations

Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo

1993 • 367 citations

Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1

1994 • 301 citations

Basic fibroblast growth factor stimulates endothelial regrowth and proliferation in denuded arteries.

1990 • 282 citations

Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3.

1992 • 263 citations

Rat carotid neointimal smooth muscle cells reexpress a developmentally regulated mRNA phenotype during repair of arterial injury.

1992 • 256 citations

Hypotensive Activity of Fibroblast Growth Factor

1991 • 246 citations

Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries.

1992 • 242 citations

FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse

1991 • 232 citations

Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells.

1988 • 214 citations

Growth factor expression in aorta of normotensive and hypertensive rats.

1989 • 195 citations

Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages.

1993 • 194 citations

Molecular cloning and characterization of 2B7, a rat mRNA which distinguishes smooth muscle cell phenotypes and is identical to osteopontin (secreted phosphoprotein I, 2aR)

1991 • 191 citations

Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study.

1993 • 174 citations

Smooth muscle cell abundance and fibroblast growth factors in coronary lesions of patients with nonfatal unstable angina. A clue to the mechanism of transformation from the stable to the unstable clinical state.

1993 • 164 citations

Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF

1994 • 163 citations

Intimal smooth muscle cell proliferation after balloon catheter injury. The role of basic fibroblast growth factor.

1992 • 161 citations

The aortic tunica media of the developing rat. I. Quantitative stereologic and biochemical analysis.

1975 • 156 citations

Developmental changes in isoactin expression in rat aortic smooth muscle cells in vivo. Relationship between growth and cytodifferentiation.

1986 • 150 citations

T lymphocytes that infiltrate tumors and atherosclerotic plaques produce heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor: a potential pathologic role.

1995 • 146 citations

Constitutive endothelin-1 overexpression promotes smooth muscle cell proliferation via an external autocrine loop

1994 • 141 citations

Induction of platelet-derived growth factor receptor expression in smooth muscle cells and fibroblasts upon tissue culturing.

1988 • 135 citations

Elimination of smooth muscle cells in experimental restenosis: targeting of fibroblast growth factor receptors.

1992 • 134 citations

Enhanced revascularization of the ischemic limb by angiogenic therapy.

1993 • 134 citations

Proliferating Arterial Smooth Muscle Cells After Balloon Injury Express TNF-α but Not Interleukin-1 or Basic Fibroblast Growth Factor

1996 • 132 citations

Smooth muscle cell immediate-early gene and growth factor activation follows vascular injury. A putative in vivo mechanism for autocrine growth.

1993 • 130 citations

Characterization of cloned aortic smooth muscle cells from young rats.

1994 • 124 citations

Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury.

1993 • 120 citations

Acidic fibroblast growth factor promotes vascular repair.

1991 • 117 citations

Developmentally timed expression of an embryonic growth phenotype in vascular smooth muscle cells.

1994 • 109 citations

Antisense Inhibition of Basic Fibroblast Growth Factor Induces Apoptosis in Vascular Smooth Muscle Cells

1996 • 105 citations

Expression of basic and acidic fibroblast growth factors and their receptor in normal and atherosclerotic human arteries

1993 • 104 citations

Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor.

1993 • 98 citations

Three forms of rat basic fibroblast growth factor are made from a single mRNA and localize to the nucleus

1991 • 94 citations

Vascular response to basic fibroblast growth factor when infused onto the normal adventitia or into the injured media of the rat carotid artery.

1991 • 92 citations

The growth and development of the rat aorta. II. Changes in nucleic acid and scleroprotein content.

1972 • 90 citations

Alpha 1-adrenergic stimulation of platelet-derived growth factor A-chain gene expression in rat aorta.

1990 • 85 citations

Morphometric study of early postnatal development of the thoracic aorta in the rat.

1980 • 82 citations

Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells. Possible mediator of the response to vascular injury.

1995 • 81 citations

Basic Fibroblast Growth Factor Dilates Rat Pial Arterioles

1994 • 78 citations

The growth and development of the rat aorta. I. Morphological aspects.

1972 • 75 citations

Proliferating cell nuclear antigen immunohistochemistry in rat aorta after balloon denudation. Comparison with thymidine and bromodeoxyuridine labeling.

1992 • 75 citations

Differential expression of mRNA coding for heparin‐binding growth factor type 2 in human cells

1988 • 63 citations

Acidic and basic fibroblast growth factors are survival factors with distinctive activity in quiescent BALB/c 3T3 murine fibroblasts.

1991 • 63 citations

Flg-2, a new member of the family of fibroblast growth factor receptors.

1991 • 54 citations

Fibroblast Growth Factor Messenger Ribonucleic Acid Expression in a Human Astrocytoma Cell Line: Regulation by Serum and Cell Density

1988 • 54 citations

Basic fibroblast growth factor regulates type I collagen and collagenase gene expression in human smooth muscle cells.

1995 • 52 citations

Comparison of gene expression in bovine aortic endothelium in vivo versus in vitro. Differences in growth regulatory molecules.

1993 • 52 citations

Up‐regulation of aFGF expression in quiescent cells is related to cell survival

1994 • 52 citations

Promoter regions involved in density-dependent regulation of basic fibroblast growth factor gene expression in human astrocytic cells.

1996 • 51 citations

The Expression Of Acidic Fibroblast Growth Gactor (Heparin-Binding Growth Factor-1) And Cytokine Genes In Human Cardiac Allografts And T Cells

1993 • 44 citations

Differences in growth factor response in smooth muscle cells isolated from adult and neonatal rat arteries

1991 • 43 citations

Fibroblast Growth Factors, Depolarization, and Substratum Interact in a Combinatorial Way to Promote Neuronal Survival

1993 • 38 citations

Effect of nerve growth factor and fibroblast growth factor on PC12 cells: inhibition by orthovanadate.

1993 • 38 citations

Expression and Regulation of mRNA Coding for Acidic and Basic Fibroblast Growth Factor and Transforming Growth Factorα in Cells Derived from Human Skin

1990 • 36 citations

Serum, phorbol ester, and polypeptide mitogens increase class 1 and 2 heparin-binding (acidic and basic fibroblast) growth factor gene expression in human vascular smooth muscle cells.

1991 • 35 citations

The Predominant Form of Fibroblast Growth Factor Receptor Expressed by Proliferating Human Arterial Smooth Muscle Cells in Culture Is Type I

1994 • 35 citations

Basic fibroblast growth factor in the extracellular matrix suppresses collagen synthesis and type III procollagen mRNA levels in arterial smooth muscle cell cultures.

1993 • 33 citations

Identification and characterization of developmentally regulated genes in vascular smooth muscle cells.

1992 • 33 citations

Human dermal fibroblasts express multiple bFGF and aFGF proteins

1991 • 32 citations

Dietary-Induced Atherosclerotic Lesions Have Increased Levels of Acidic FGF mRNA and Altered Cytoskeletal and Extracellular Matrix mRNA Expression

1993 • 31 citations

Differential regulation of acidic and basic fibroblast growth factor gene expression in fibroblast growth factor-treated rat aortic smooth muscle cells.

1994 • 31 citations

Human fibroblast growth factor 1 gene expression in vascular smooth muscle cells is modulated via an alternate promoter in response to serum and phorbol ester

1995 • 30 citations

Changes in vessel wall plasminogen activator activity and smooth muscle cell proliferation and activation after arterial injury

1995 • 28 citations

Suppression of neointimal lesions after vascular injury: a role for polyclonal anti-basic fibroblast growth factor antibody.

1994 • 28 citations

Cellular Adhesion Regulates bFGF Gene Expression in Human Retinal Pigment Epithelial Cells

1994 • 27 citations

Modulation of bFGF in lung fibroblasts by TGF-beta and PDGF

1991 • 26 citations

Methodologic considerations important in the accurate quantitation of aortic smooth muscle cell replication in the normal rat.

1991 • 25 citations

Regulation of Basic Fibroblast Growth Factor mRNA Expression in Rat C6 Glioma Cells

1993 • 22 citations

Fibroblast growth factor receptor-1 expression is associated with neointimal formation in vitro.

1996 • 21 citations

Cyclic AMP, Early Response Gene Expression, and DNA Synthesis in Rat Smooth Muscle Cells

1994 • 21 citations

Increasing cell density down-regulates the expression of acidic FGF by human RPE cellsin vitro

1993 • 17 citations

Endogenous activation of c-myc expression and DNA synthesis in serum-starved neonatal rat smooth muscle cells

1993 • 15 citations

Heterogeneity of rat aortic smooth muscle cell replication during development: correlation with replicative activity after experimental endothelial denudation in adults.

1994 • 14 citations

Cardiovascular Effects of Basic Fibroblast Growth Factor in Rats

1994 • 14 citations

Growth factor persistence after vessel wall injury in a rabbit angioplasty model

1994 • 12 citations

Use of vascular smooth-muscle single cell suspensions for rapid cell number determination in rat thoracic aorta media layer

1982 • 12 citations

Expression of basic fibroblast growth factor and fibroblast growth factor receptor genes in cultured rat aortic smooth muscle cells

1995 • 11 citations

Effect of ploidy on transcription levels in cultured rat aortic smooth muscle cells

1992 • 7 citations