The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism
Data up to Jan 2025
Total Citations Per Year
Abstract
References (52)
Methods of enzymatic analysis
1964 • 5,230 citations
Titration of free fatty acids of plasma: a study of current methods and a new modification
1960 • 1,036 citations
Role of Insulin in Endogenous Hypertriglyceridemia*
1967 • 523 citations
The cause of hepatic accumulation of fructose 1-phosphate on fructose loading
1970 • 404 citations
Effect of Insulin on Adenosine 3‘,5‘-Monophosphate in the Rat Epididymal Fat Pad
1966 • 340 citations
Role of Adenosine 3′,5′-Monophosphate in the Effects of Insulin and Anti-insulin Serum on Liver Metabolism
1968 • 328 citations
Assimilation and dissimilation of fatty acids by the rat liver
1959 • 265 citations
Glucose, insulin, and triglyceride responses to high and low carbohydrate diets in man.
1966 • 261 citations
The Effects of Glucagon, Dibutyryl Cyclic Adenosine 3',5'-Monophosphate, and Concentration of Free Fatty Acid on Hepatic Lipid Metabolism
1969 • 252 citations
Electron microscopic and biochemical study of lipoprotein synthesis in the isolated perfused rat liver
1967 • 243 citations
Adipose Tissue. Regulation and Metabolic Functions.
1971 • 217 citations
Very low density lipoproteins in intestinal lymph: origin, composition, and role in lipid transport in the fasting state
1969 • 214 citations
Regulation of Fat Metabolism in the Liver
1967 • 186 citations
Feeding and breeding of laboratory animals. IX. A complete cubed diet for mice and rats
1949 • 177 citations
Very low density lipoproteins in intestinal lymph: role in triglyceride and cholesterol transport during fat absorption
1969 • 177 citations
De novo synthesis of fatty acid in perfused rat liver as a determinant of plasma lipoprotein production
1967 • 168 citations
Determination of serum glycerides.
1959 • 161 citations
Dietary Sugar in the Production of Hyperglyceridemia
1965 • 159 citations
Use of multicompartmental models to measure rates of triglyceride metabolism in rats
1964 • 158 citations
THE BIOSYNTHESIS OF RADIOACTIVE FATTY ACIDS AND CHOLESTEROL
1950 • 138 citations
STUDIES ON CARBOHYDRATE METABOLISM IN RAT LIVER SLICES
1955 • 134 citations
Control of Plasma and Liver Triglyceride Kinetics by Carbohydrate Metabolism and Insulin
1969 • 132 citations
Enzymes Involved in Fructose Metabolism in Liver and the Glyceraldehyde Metabolic Crossroads
1969 • 127 citations
Interrelationships of Hyperinsulinism and Hypertriglyceridemia in Young Patients with Coronary Heart Disease
1968 • 120 citations
Ketogenic and lipolytic effects of glucagon on liver
1966 • 112 citations
Metabolism of Insulin-I131 Studies in Isolated, Perfused Rat Liver and Hind-limb Preparations
1959 • 104 citations
Influence of insulin on cyclic 3?,5?-AMP phosphodiesterase activity in liver, skeletal muscle, adipose tissue, and kidney
1968 • 104 citations
THE EFFECT OF INSULIN ON LIPOLYSIS.
1964 • 87 citations
Interactions of Glucagon and Insulin on the Metabolism of Perfused Livers from Fasted Rats
1969 • 84 citations
Interactions of Obesity, and Glucose and Insulin Levels in Hypertriglyceridemia
1968 • 81 citations
Regulation of Unesterified Fatty Acids of the Plasma During the Onset of Starvation
1962 • 75 citations
The Relation of Insulin to Liver Metabolism
1956 • 72 citations
The regulation of glucose uptake in muscle as studied in the perfused rat heart.
1961 • 70 citations
Determination of 14C-labelled ketone bodies by liquid-scintillation counting
1967 • 59 citations
Alloxan Diabetes and Demonstrated Direct Action of Insulin on Metabolism of Isolated Perfused Rat Liver
1957 • 56 citations
Dietary Carbohydrates in Hyperlipemia (Hyperglyceridemia); Hepatic and Adipose Tissue Lipogenic Activities
1967 • 54 citations
Different rates of glucose and fructose metabolism in rat liver tissue in vitro
1971 • 53 citations
Inhibition of glucagon‐stimulated adenyl cyclase by insulin
1971 • 51 citations
Metabolism of intravenously infused fructose in man.
1953 • 47 citations
The effects of various dietary carbohydrates on the serum lipids during a five-day regimen.
1965 • 45 citations
The Metabolism of Intraportally Injected Fructose in Rat Liver in Vivo
1962 • 37 citations
Feeding and breeding of laboratory animals
1947 • 28 citations
The synergistic effect of cortisone and insulin on lipogenesis in the perfused rat liver as studied with α-C14-acetate
1951 • 28 citations
Sugar intake, serum insulin and platelet adhesiveness in men with and without peripheral vascular disease
1969 • 27 citations
Studies of the Metabolism of Isolated Livers of Normal and Alloxan-diabetic Rats Perfused with Insulin
1968 • 22 citations
The effect of glucagon on the state of lysosomal enzymes in isolated perfused rat liver
1970 • 22 citations
Hormonal Influence upon the in Vitro Synthesis of Radioactive Fatty Acids
1951 • 20 citations
A computer programme for the calculation of radioactivity data from liquid-scintillation counters fitted with external standards
1967 • 19 citations
Effect of oleate concentration on its metabolism by the perfused rat liver
1968 • 18 citations
[Metabolite model in rat liver following application of fructose].
1969 • 8 citations
Hormone stimulation of ketogenesis in rat liver homogenates
1969 • 8 citations
THE CONTROL OF BLOOD SUGAR IN THE LABORATORY RAT AND GOLDEN HAMSTER
1969 • 3 citations