Frequent and extensive deletion during the 9,22 translocation in CML

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1983 • 848 citations

Evidence for a multistep pathogenesis of chronic myelogenous leukemia

1981 • 331 citations

Chromosomal localization of human cellular homologues of two viral oncogenes

1982 • 304 citations

Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration.

1985 • 282 citations

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.

1985 • 266 citations

Evidence of a New Chimericbcr/c-ablmRNA in Patients with Chronic Myelocytic Leukemia and the Philadelphia Chromosome

1985 • 253 citations

An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.

1984 • 210 citations

Altered Transcription of the c- abl Oncogene in K-562 and Other Chronic Myelogenous Leukemia Cells

1984 • 209 citations

A normal cell protein cross-reactive to the major Abelson murine leukaemia virus gene product

1979 • 146 citations

Late-appearing Philadelphia chromosome in two patients with chronic myelogenous leukemia

1980 • 69 citations

The human v-abl cellular homologue.

1983 • 64 citations

Variable breakpoints on the Philadelphia chromosome in chronic myelogenous leukemia

1985 • 58 citations

Expression of a translocated c-abl gene in hybrids of mouse fibroblasts and chronic myelogenous leukaemia cells

1986 • 31 citations

Increased expression of a novel c-abl-related RNA in K562 cells

1985 • 28 citations