Sarcopenia and cachexia in the era of obesity: clinical and nutritional impact

Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

2008 • 2,734 citations

Cancer Cachexia in the Age of Obesity: Skeletal Muscle Depletion Is a Powerful Prognostic Factor, Independent of Body Mass Index

2013 • 2,226 citations

A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care

2008 • 1,819 citations

Total body skeletal muscle and adipose tissue volumes: estimation from a single abdominal cross-sectional image

2004 • 1,489 citations

Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography

1998 • 1,418 citations

Sarcopenia as a Determinant of Chemotherapy Toxicity and Time to Tumor Progression in Metastatic Breast Cancer Patients Receiving Capecitabine Treatment

2009 • 999 citations

ESPEN Guidelines on Enteral Nutrition: Non-surgical oncology

2006 • 922 citations

An overview of sarcopenia: facts and numbers on prevalence and clinical impact

2010 • 760 citations

Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis

2011 • 738 citations

Sarcopenia is associated with postoperative infection and delayed recovery from colorectal cancer resection surgery

2012 • 717 citations

Visceral abdominal-fat accumulation associated with use of indinavir

1998 • 717 citations

Diagnostic Criteria for the Classification of Cancer-Associated Weight Loss

2014 • 655 citations

Sarcopenia in an Overweight or Obese Patient Is an Adverse Prognostic Factor in Pancreatic Cancer

2009 • 622 citations

Measurement of skeletal muscle radiation attenuation and basis of its biological variation

2014 • 584 citations

Body Composition as an Independent Determinant of 5-Fluorouracil–Based Chemotherapy Toxicity

2007 • 548 citations

Changes in Weight, Body Composition, and Factors Influencing Energy Balance Among Premenopausal Breast Cancer Patients Receiving Adjuvant Chemotherapy

2001 • 532 citations

Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality

2007 • 516 citations

Muscle loss and obesity: the health implications of sarcopenia and sarcopenic obesity

2015 • 495 citations

Sarcopenic obesity: A Critical appraisal of the current evidence

2012 • 494 citations

Lean Tissue Imaging

2014 • 464 citations

Functional Compromise Reflected by Sarcopenia, Frailty, and Nutritional Depletion Predicts Adverse Postoperative Outcome After Colorectal Cancer Surgery

2014 • 453 citations

Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis

2015 • 451 citations

Body composition in patients with non−small cell lung cancer: a contemporary view of cancer cachexia with the use of computed tomography image analysis

2010 • 429 citations

Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial

2013 • 428 citations

Sarcopenia negatively impacts short-term outcomes in patients undergoing hepatic resection for colorectal liver metastasis

2011 • 385 citations

Sarcopenia Impacts on Short- and Long-term Results of Hepatectomy for Hepatocellular Carcinoma

2014 • 352 citations

Sarcopenia is a Negative Prognostic Factor After Curative Resection of Colorectal Cancer

2015 • 323 citations

Sarcopenia Predicts Early Dose-Limiting Toxicities and Pharmacokinetics of Sorafenib in Patients with Hepatocellular Carcinoma

2012 • 284 citations

Obesity paradox in cancer: new insights provided by body composition

2014 • 282 citations

Association of Skeletal Muscle Wasting With Treatment With Sorafenib in Patients With Advanced Renal Cell Carcinoma: Results From a Placebo-Controlled Study

2010 • 273 citations

Ethnicity‐related skeletal muscle differences across the lifespan

2009 • 264 citations

The Clinical Guide to Oncology Nutrition

2000 • 262 citations

Sarcopenia as a Prognostic Factor among Patients with Stage III Melanoma

2011 • 258 citations

Sarcopenia is associated with toxicity in patients undergoing neo-adjuvant chemotherapy for oesophago-gastric cancer

2014 • 253 citations

Sarcopenia is an independent predictor of complications following pancreatectomy for adenocarcinoma

2014 • 252 citations

Impact of preoperative quality as well as quantity of skeletal muscle on survival after resection of pancreatic cancer

2015 • 248 citations

The emerging role of computerized tomography in assessing cancer cachexia

2009 • 243 citations

Sarcopenia as a Prognostic Index of Nutritional Status in Concurrent Cirrhosis and Hepatocellular Carcinoma

2013 • 237 citations

Sarcopenic Obesity: Does Muscle Loss Cause Fat Gain?: Lessons from Rheumatoid Arthritis and Osteoarthritis^a

2000 • 229 citations

Sarcopenia Is Linked to Treatment Toxicity in Patients With Metastatic Colorectal Cancer

2014 • 224 citations

Sarcopenia and body mass index predict sunitinib-induced early dose-limiting toxicities in renal cancer patients

2013 • 216 citations

Central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential?

2013 • 211 citations

Anamorelin for patients with cancer cachexia: an integrated analysis of two phase 2, randomised, placebo-controlled, double-blind trials

2014 • 192 citations

Changes in skeletal muscle mass during palliative chemotherapy in patients with advanced lung cancer

2014 • 191 citations

Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food

2011 • 190 citations

Sarcopenia is a Predictor of Postoperative Respiratory Complications in Patients with Esophageal Cancer

2015 • 174 citations

Cancer-Associated Cachexia and Underlying Biological Mechanisms

2006 • 171 citations

Sarcopenic obesity: A probable risk factor for dose limiting toxicity during neo-adjuvant chemotherapy in oesophageal cancer patients

2015 • 157 citations

An exploratory study of body composition as a determinant of epirubicin pharmacokinetics and toxicity

2010 • 152 citations

Sarcopenia is an independent prognostic factor in elderly patients with diffuse large B-cell lymphoma treated with immunochemotherapy

2013 • 140 citations

Loss of Skeletal Muscle Mass During Neoadjuvant Chemoradiotherapy Predicts Postoperative Mortality in Esophageal Cancer Surgery

2015 • 133 citations

Negative Impact of Skeletal Muscle Loss after Systemic Chemotherapy in Patients with Unresectable Colorectal Cancer

2015 • 133 citations

Two faces of drug therapy in cancer: drug-related lean tissue loss and its adverse consequences to survival and toxicity

2011 • 129 citations

Sarcopenia as a Prognostic Biomarker of Advanced Urothelial Carcinoma

2015 • 127 citations

The Prevalence of Sarcopenia in Patients With Respiratory Failure Classified as Normally Nourished Using Computed Tomography and Subjective Global Assessment

2013 • 125 citations

Nutritional support of the oncology patient

2013 • 121 citations

Normal protein anabolic response to hyperaminoacidemia in insulin-resistant patients with lung cancer cachexia

2012 • 118 citations

Sarcopenia as a predictor of overall survival after cytoreductive nephrectomy for metastatic renal cell carcinoma

2015 • 117 citations

Are sarcopenia, obesity and sarcopenic obesity predictive of outcome in patients with colorectal liver metastases?

2014 • 115 citations

Dietary patterns in patients with advanced cancer: implications for anorexia-cachexia therapy

2006 • 108 citations

Body Composition Variation and Impact of Low Skeletal Muscle Mass in Patients With Advanced Medullary Thyroid Carcinoma Treated With Vandetanib: Results From a Placebo-Controlled Study

2013 • 97 citations

Body Composition by Computed Tomography as a Predictor of Toxicity in Patients With Renal Cell Carcinoma Treated With Sunitinib

2014 • 92 citations

Skeletal Muscle Depletion is Associated with Severe Postoperative Complications in Patients Undergoing Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis of Colorectal Cancer

2015 • 90 citations

A critical evaluation of body composition modalities used to assess adipose and skeletal muscle tissue in cancer

2012 • 84 citations

Assessment of Nutritional Status in Cancer – The Relationship Between Body Composition and Pharmacokinetics

2013 • 77 citations

Sarcopenia and Physical Function: In Overweight Patients with Advanced Cancer

2013 • 73 citations

Automated segmentation of muscle and adipose tissue on CT images for human body composition analysis

2009 • 66 citations

Habitual Myofibrillar Protein Synthesis Is Normal in Patients with Upper GI Cancer Cachexia

2014 • 66 citations

Body composition in chemotherapy

2013 • 64 citations

The association between body composition and toxicities from the combination of Doxil and trabectedin in patients with advanced relapsed ovarian cancer

2014 • 48 citations

Role of the lean body mass and of pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of sunitinib in cancer patients

2014 • 47 citations

Metabolism in patients with small cell lung carcinoma compared with patients with non-small cell lung carcinoma and healthy controls

1997 • 43 citations

Reversible sarcopenia in patients with gastrointestinal stromal tumor treated with imatinib

2015 • 36 citations

Dietary Patterns of Patients: With Advanced Lung or Colorectal Cancer

2012 • 27 citations

Nutritional advances in patients with respiratory diseases

2015 • 12 citations

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