Body Composition Variation and Impact of Low Skeletal Muscle Mass in Patients With Advanced Medullary Thyroid Carcinoma Treated With Vandetanib: Results From a Placebo-Controlled Study

Definition and classification of cancer cachexia: an international consensus

2011 • 4,715 citations

Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

2008 • 2,734 citations

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

2001 • 2,539 citations

A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care

2008 • 1,819 citations

Total body skeletal muscle and adipose tissue volumes: estimation from a single abdominal cross-sectional image

2004 • 1,489 citations

Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography

1998 • 1,418 citations

Vandetanib in Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer: A Randomized, Double-Blind Phase III Trial

2011 • 1,409 citations

Medullary Thyroid Cancer: Management Guidelines of the American Thyroid Association

2009 • 1,316 citations

Sarcopenia as a Determinant of Chemotherapy Toxicity and Time to Tumor Progression in Metastatic Breast Cancer Patients Receiving Capecitabine Treatment

2009 • 999 citations

Sarcopenia in an Overweight or Obese Patient Is an Adverse Prognostic Factor in Pancreatic Cancer

2009 • 622 citations

Body Composition as an Independent Determinant of 5-Fluorouracil–Based Chemotherapy Toxicity

2007 • 548 citations

Molecular mechanisms modulating muscle mass

2003 • 428 citations

Low body mass index and sarcopenia associated with dose-limiting toxicity of sorafenib in patients with renal cell carcinoma

2010 • 411 citations

Vascular endothelial growth factor stimulates skeletal muscle regeneration in Vivo

2004 • 321 citations

Sarcopenia Predicts Early Dose-Limiting Toxicities and Pharmacokinetics of Sorafenib in Patients with Hepatocellular Carcinoma

2012 • 284 citations

Association of Skeletal Muscle Wasting With Treatment With Sorafenib in Patients With Advanced Renal Cell Carcinoma: Results From a Placebo-Controlled Study

2010 • 273 citations

Population pharmacokinetics of imatinib and the role of α₁‐acid glycoprotein

2006 • 177 citations

Pharmacokinetic-Pharmacodynamic Relationships of Imatinib and Its Main Metabolite in Patients with Advanced Gastrointestinal Stromal Tumors

2006 • 155 citations

Body fat redistribution after weight gain in women with anorexia nervosa 1–3

2005 • 117 citations

Angiogenesis Associated With Visceral and Subcutaneous Adipose Tissue in Severe Human Obesity

2008 • 114 citations

Skeletal muscle anabolism is a side effect of therapy with the MEK inhibitor: selumetinib in patients with cholangiocarcinoma

2012 • 102 citations

Activated Forms of VEGF-C and VEGF-D Provide Improved Vascular Function in Skeletal Muscle

2009 • 99 citations

Adipose tissue distribution after weight restoration and weight maintenance in women with anorexia nervosa

2009 • 44 citations

Vandetanib for the Treatment of Thyroid Cancer

2011 • 42 citations

Rapid and sensitive LC/MS/MS analysis of the novel tyrosine kinase inhibitor ZD6474 in mouse plasma and tissues

2005 • 31 citations

Molecular Targeted Therapies for Patients with Refractory Thyroid Cancer

2010 • 27 citations