Thrombopoietin and Its Receptor, c-mpl, Are Constitutively Expressed by Mouse Liver Endothelial Cells: Evidence of Thrombopoietin as a Growth Factor for Liver Endothelial Cells

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

1994 • 1,328 citations

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

1994 • 1,138 citations

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

1994 • 1,081 citations

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI

1994 • 987 citations

c-Mpl ligand is a humoral regulator of megakaryocytopoiesis

1994 • 689 citations

The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse

1985 • 689 citations

Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.

1992 • 525 citations

A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors

1990 • 404 citations

Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis

1993 • 359 citations

Regulation of megakaryocytopoiesis

1989 • 305 citations

Localization and Regulation of Thrombopoietin mRNA Expression in Human Kidney, Liver, Bone Marrow, and Spleen Using In Situ Hybridization

1997 • 289 citations

Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion

1994 • 287 citations

The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets

1995 • 286 citations

Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets

1996 • 269 citations

Murine thrombopoietin mRNA levels are modulated by platelet count

1995 • 200 citations

Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.

1993 • 174 citations

MPLV: A retrovirus complex inducing an acute myeloproliferative leukemic disorder in adult mice

1986 • 140 citations

Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice

1996 • 112 citations

Extramedullary hematopoiesis in the adult mouse liver is associated with specific hepatic sinusoidal endothelial cells

1997 • 83 citations

Production of thrombopoietin (TPO) by rat hepatocytes and hepatoma cell lines.

1995 • 79 citations

Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization.

1997 • 74 citations

Differences in the lectin-binding patterns of the periportal and perivenous endothelial domains in the liver sinusoids

1991 • 53 citations

Isolation and enrichment of two sublobular compartment-specific endothelial cell subpopulations from liver sinusoids

1993 • 42 citations

The effect of massive liver resection on platelet kinetics in the rat.

1975 • 42 citations

THROMBOPENIA AND INCREASED CAPILLARY FRAGILITY IN HEPATIC DISEASE

1949 • 26 citations

Role of Periportal and Perivenous Sinusoidal Endothelial Cells in Hepatic Homing of Blood and Metastatic Cancer Cells

1993 • 24 citations

Differential location of hemopoietic colonies within liver acini of postnatal and phenylhydrazine-treated adult mice

1989 • 24 citations

Hepatitis B virus DNA forms in the liver of chronically infected individuals

1989 • 8 citations