Calcium signals and phospholipid methylation in eukaryotic cells

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1980 • 2,218 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

A non-disruptive technique for loading calcium buffers and indicators into cells

1981 • 1,121 citations

Phospholipid Methylation and Biological Signal Transmission

1980 • 1,101 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

Calcium in biological systems

1976 • 550 citations

The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions

1981 • 518 citations

Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes.

1983 • 466 citations

Synthesis of lecithins by acylation of O-(sn-glycero-3-phosphoryl) choline with fatty acid anhydrides

1969 • 333 citations

Chemoattractants stimulate degradation of methylated phospholipids and release of arachidonic acid in rabbit leukocytes.

1979 • 279 citations

Stimulation of phospholipid methylation, Ca2+ influx, and histamine release by bridging of IgE receptors on rat mast cells.

1980 • 256 citations

Intracellular calcium measurements by 19F NMR of fluorine-labeled chelators.

1983 • 190 citations

Activation of Phospholipid Metabolism During Mediator Release from Stimulated Rat Mast Cells

1979 • 165 citations

Relationship between enhanced turnover of phosphatidylinositol and lymphocyte activation by mitogens

1975 • 153 citations

S‐ADENOSYLMETHIONINE IN BRAIN AND OTHER TISSUES

1966 • 143 citations

Formation, functions and regulatory importance of S-adenosyl-l-methionine

1971 • 134 citations

Concanavalin A stimulates phospholipid methylation and phosphatidylserine decarboxylation in rat mast cells.

1979 • 132 citations

Phospholipid methylation: a biochemical signal modulating lymphocyte mitogenesis.

1980 • 129 citations

Phospholipid methylation and phospholipase A2 activation in cytotoxicity by human natural killer cells.

1981 • 123 citations

Is phosphatidylinositol really out of the calcium gate?

1982 • 121 citations

Inositol lipid metabolism in dividing and differentiating cells

1982 • 119 citations

Binding Parameters of the Interaction Between Rat IgE and Rat Mast Cell Receptors

1975 • 116 citations

2 Calcium and Histamine Secretion from Mast Cells

1982 • 114 citations

What is the function of phospholipid N-methylation?

1983 • 114 citations

Interactions of lysophospholipids and mast cells

1979 • 112 citations

Evidence for a role of phosphatidylinositol turnover in stimulus–secretion coupling. Studies with rat peritoneal mast cells

1979 • 107 citations

Phospholipid methylation affects immunoglobulin E-mediated histamine and arachidonic acid release in rat leukemic basophils

1980 • 106 citations

IgE-mediated histamine release in rat basophilic leukemia cells: Receptor activation, phospholipid methylation, Ca2+ flux, and release of arachidonic acid

1981 • 103 citations

The possible functional significance of phosphatidylethanolamine methylation

1980 • 100 citations

Measurements of S-adenosylmethionine and L-homocysteine metabolism in cultured human lymphoid cells.

1983 • 100 citations

Release of arachidonic acid from human lymphocytes in response to mitogenic lectins.

1979 • 91 citations

Bradykinin stimulates phospholipid methylation, calcium influx, prostaglandin formation, and cAMP accumulation in human fibroblasts.

1983 • 85 citations

Some mitogens cause rapid increases in free calcium in fibroblasts

1984 • 83 citations

Interaction of Concanavalin A with Rat Lymphocytes

1972 • 82 citations

A new concept of triggering mechanisms of IgE-mediated histamine release

1978 • 81 citations

Concanavalin A-Induced Histamine Release from Normal Rat Mast Cells

1975 • 73 citations

Phospholipase activation in the IgE-mediated and Ca2+ ionophore A23187-induced release of histamine from rat basophilic leukemia cells

1981 • 72 citations

Analysis of the stimulation-inhibition paradox exhibited by lymphocytes exposed to concanavalin A.

1976 • 68 citations

Phospholipid metabolism, calcium flux, and the receptor-mediated induction of chemotaxis in rabbit neutrophils.

1982 • 64 citations

Nonpolar lipid methylation. Biosynthesis of fatty acid methyl esters by rat lung membranes using S-adenosylmethionine.

1981 • 62 citations

The exogenous lipid requirement for histamine release from rat peritoneal mast cells stimulated by concanavalin A

1979 • 57 citations

Concanavalin A, a model "antigen" for the in vitro detection of cell-bound reaginic antibody in the rat.

1973 • 55 citations

Changes in histamine synthetic activity, histamine content and responsiveness to compound 48/80 with maturation of rat peritoneal mast cells.

1983 • 50 citations

Purification of rat peritoneal mast cells: occupation of IgE-receptors by IgE prevents loss of the receptors.

1980 • 48 citations

Functional mosaicism of the lymphocyte plasma membrane. Characterization of membrane subfractions obtained by affinity chromatography on concanavalin A-Sepharose

1978 • 41 citations

Rat basophilic leukemia cell lines defective in phospholipid methyltransferase enzymes, Ca2+ influx, and histamine release: reconstitution by hybridization.

1981 • 41 citations

Phosphatidylinositol metabolism in mast cells and neutrophils

1982 • 41 citations

Early increases in phospholipid methylation are not necessary for the mitogenic stimulation of lymphocytes.

1982 • 40 citations

Microsomal phosphatidylethanolamine methyltransferase: Some physical and kinetic properties

1981 • 38 citations

Duration of the calcium signal in the mitogenic stimulation of thymocytes

1983 • 35 citations

Evidence for de novo synthesis of phosphatidylinositol coupled with histamine release in activated rat mast cells

1983 • 30 citations

5-Hydroxytryptamine stimulation of phosphatidylinositol hydrolysis and calcium signalling in the blowfly salivary gland

1982 • 28 citations

Identification of ubiquinone-50 as the major methylated nonpolar lipid in human monocytes. Regulation of its biosynthesis via methionine-dependent pathways and relationship to superoxide production.

1983 • 20 citations

Contemporary Metabolism

1982 • 19 citations

Mitogenic stimulation and the redistribution of concanavalin A receptors on lymphocytes

1981 • 18 citations

Structural requirements of the phospholipid substrate for phospholipid N-methylation in rat liver

1983 • 18 citations

Enhanced phospholipid metabolism in rat mast cells stimulated to release histamine.

1980 • 18 citations

Large effects of preparative techniques on lymphocyte cyclic AMP content

1983 • 15 citations