Phospholipid Methylation and Biological Signal Transmission

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Surface Modulation in Cell Recognition and Cell Growth

1976 • 1,062 citations

Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture

1974 • 1,037 citations

[16] Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes

1974 • 1,028 citations

Membrane Asymmetry

1977 • 965 citations

Dynamics of the Hydrocarbon Layer in Liposomes of Lecithin and Sphingomyelin Containing Dicetylphosphate

1974 • 942 citations

The Pineal Gland: A Neurochemical Transducer

1974 • 872 citations

A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids.

1980 • 841 citations

Methyl transfering enzyme system of microsomes in the biosynthesis of lecithin (phosphatidylcholine)

1961 • 542 citations

The role of lipids in platelet function: with particular reference to the arachidonic acid pathway.

1978 • 364 citations

Enzymatic methylation of phosphatidylethanolamine increases erythrocyte membrane fluidity

1978 • 356 citations

Lysolecithin and Cell Fusion

1970 • 350 citations

beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling.

1979 • 308 citations

Chemoattractants stimulate degradation of methylated phospholipids and release of arachidonic acid in rabbit leukocytes.

1979 • 279 citations

Stimulation of phospholipid methylation, Ca2+ influx, and histamine release by bridging of IgE receptors on rat mast cells.

1980 • 256 citations

Action of highly purified phospholipases on blood platelets. Evidence for an asymmetric distribution of phospholipids in the surface membrane

1977 • 248 citations

Identification and properties of two methyltransferases in conversion of phosphatidylethanolamine to phosphatidylcholine.

1978 • 221 citations

Identification and Properties of Methyltransferases That Synthesize Phosphatidylcholine in Rat Brain Synaptosomes

1980 • 212 citations

CHARACTERIZATION OF BENZODIAZEPINE BINDING SITES IN CULTURED CELLS OF NEURAL ORIGIN

1979 • 204 citations

Mode of coupling between hormone receptors and adenylate cyclase elucidated by modulation of membrane fluidity

1978 • 202 citations

Enzymatic synthesis and rapid translocation of phosphatidylcholine by two methyltransferases in erythrocyte membranes.

1978 • 199 citations

The Enzymatic Conversion of Phospholipid Ethanolamine to Phospholipid Choline in Rat Liver

1961 • 193 citations

Biology of immunoglobulin E. Molecular basis of reaginic hypersensitivity.

1975 • 191 citations

Phospholipid Methylation Unmasks Cryptic β-Adrenergic Receptors in Rat Reticulocytes

1979 • 179 citations

Requirement of S-adenosyl-L-methionine-mediated methylation for human monocyte chemotaxis.

1978 • 169 citations

Supersensitivity and Subsensitivity of the β-Adrenergic Receptor in Pineal Gland Regulated by Catecholamine Transmitter

1973 • 161 citations

Mepacrine blocks beta-adrenergic agonist-induced desensitization in astrocytoma cells.

1980 • 151 citations

Adenosylhomocysteine hydrolase. Crystallization of the purified enzyme and its properties.

1978 • 145 citations

Rapid transmembrane movement of newly synthesized phospholipids during membrane assembly.

1977 • 142 citations

Effect of the lipid environment on protein motion and enzymatic activity of sarcoplasmic reticulum calcium ATPase.

1978 • 141 citations

Transmembrane potentials and phospholipid flip-flop in excitable membrane vesicles

1973 • 133 citations

Concanavalin A stimulates phospholipid methylation and phosphatidylserine decarboxylation in rat mast cells.

1979 • 132 citations

Phospholipid methylation: a biochemical signal modulating lymphocyte mitogenesis.

1980 • 129 citations

Benzodiazepine and β-adrenergic receptor ligands independently stimulate phospholipid methylation

1979 • 128 citations

Increased Ca2+-ATPase activity associated with methylation of phospholipids in human erythrocytes

1979 • 118 citations

Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.

1976 • 116 citations

Methylation of Ethanolamine Phosphatides by Microsomes from Normal and Mutant Strains of Neurospora crassa

1967 • 113 citations

Phospholipid methylation affects immunoglobulin E-mediated histamine and arachidonic acid release in rat leukemic basophils

1980 • 106 citations

Lectins from Wistaria floribunda seeds and their effect on membrane fluidity of human peripheral lymphocytes.

1975 • 103 citations

Induction of calcium flux across the rat mast cell membrane by bridging IgE receptors.

1979 • 101 citations

Immune Mechanisms of Reversed Type Reaginic Hypersensitivity

1969 • 101 citations

Phospholipase A and the mechanism of action of aldosterone

1978 • 98 citations

Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: Evidence for a methylation reaction essential to cytolysis

1978 • 97 citations

Evidence for an Asymmetric Distribution of Phospholipids in the Human Erythrocyte Membrane

1974 • 86 citations

Phospholipid methylation in macrophages is inhibited by chemotactic factors

1979 • 77 citations

Current concepts on the secretory function of mast cells

1975 • 69 citations

Involvement of cyclic amp and protein synthesis in catecholamine refractoriness.

1978 • 67 citations

Altered adenosine cyclic 3',5'-monophosphate synthesis and degradation by C-6 astrocytoma cells following prolonged exposure to norepinephrine.

1976 • 65 citations

Adenosylhomocysteine hydrolase inhibitors: Synthesis of 5′-deoxy-5′-(isobutylthio)-3-deazaadenosine and its effect on Rous sarcoma virus and Gross murine leukemia virus

1978 • 62 citations

Phospholipid methylation stimulates lactogenic binding in mouse mammary gland membranes.

1979 • 49 citations

Does lectin–receptor complex formation produce zones of restricted mobility within the membrane?

1979 • 46 citations

The role of guanyl nucleotides in the expression on of catecholamine-responsive adenylate cyclase during maturation of the rat reticulocyte.

1977 • 38 citations

Transbilayer disposition of the phospholipid annulus surrounding a calcium transport protein

1978 • 36 citations

Phosphatidase A activity of isolated rat mast cells and of red blood cells, white blood cells and spinal ganglion cells

1965 • 19 citations