Stat1 Is Induced and Activated by All-Trans Retinoic Acid in Acute Promyelocytic Leukemia Cells

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A Laboratory manual

1989 • 6,833 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

1990 • 1,349 citations

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

1991 • 1,298 citations

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments]

1990 • 1,224 citations

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)

1991 • 884 citations

Alpha Interferon for Induction of Remission in Hairy-Cell Leukemia

1984 • 833 citations

Cell Growth Arrest and Induction of Cyclin-Dependent Kinase Inhibitor p21 ^WAF1/CIP1 Mediated by STAT1

1996 • 796 citations

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.

1992 • 661 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

1990 • 650 citations

Interferon Alfa-2a as Compared with Conventional Chemotherapy for the Treatment of Chronic Myeloid Leukemia

1994 • 592 citations

Acute promyelocytic leukemia: from genetics to treatment

1994 • 474 citations

Anti-Oncogenic and Oncogenic Potentials of Interferon Regulatory Factors-1 and -2

1993 • 449 citations

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins.

1992 • 387 citations

Acute promyelocytic leukemia: from genetics to treatment

1994 • 384 citations

Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor, IRF-1

1989 • 368 citations

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

1994 • 359 citations

Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.

1991 • 278 citations

A single DNA response element can confer inducibility by both alpha- and gamma-interferons.

1989 • 262 citations

A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter.

1993 • 256 citations

Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes.

1988 • 228 citations

Induction of the PML protein by interferons in normal and APL cells.

1995 • 216 citations

Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias.

1990 • 212 citations

Structure of two forms of the interferon-induced (2′-5′) oligo A synthetase of human cells based on cDNAs and gene sequences.

1985 • 201 citations

Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene.

1988 • 190 citations

Complementary DNA sequence of a human cytoplasmic actin

1983 • 123 citations

Kappa B site-dependent activation of the interleukin-2 receptor alpha-chain gene promoter by human c-Rel.

1992 • 87 citations

Sequence of a cDNA coding for human IRF-1

1989 • 74 citations

Retinoic acid and granulocyte colony-stimulating factor synergistically induce leukocyte alkaline phosphatase in acute promyelocytic leukemia cells

1994 • 70 citations

AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells

1996 • 65 citations

Retinoic acid and granulocyte colony-stimulating factor synergistically induce leukocyte alkaline phosphatase in acute promyelocytic leukemia cells

1994 • 62 citations

Interferons induce xanthine dehydrogenase gene expression in L929 cells

1992 • 57 citations

Functional antagonism between the estrogen receptor and Fos in the regulation of c-fos protooncogene transcription.

1993 • 43 citations

All-trans retinoic acid and cyclic adenosine monophosphate cooperate in the expression of leukocyte alkaline phosphatase in acute promyelocytic leukemia cells

1995 • 42 citations

Interferons induce normal and aberrant retinoic-acid receptors type α in acute promyelocytic leukemia cells: Potentiation of the induction of retinoid-dependent differentiation markers

1996 • 25 citations

Growth inhibition of human acute promyelocytic leukemia NB-4 cells by interferons and all-trans retinoic acid: trans-modulation of inducible gene expression pathways.

1995 • 14 citations

Tyrosine Kinases but Not cAMP-Dependent Protein Kinase Mediate the Induction of Leukocyte Alkaline Phosphatase by Granulocyte-Colony-Stimulating Factor and Retinoic Acid in Acute Promyelocytic Leukemia Cells

1995 • 13 citations