Is prophylactic cranial irradiation indicated in small-cell lung cancer?

The central nervous system in childhood leukemia.II. Subacute leukoencephalopathy

1975 • 484 citations

CNS metastases in small cell bronchogenic carcinoma.Increasing frequency and changing pattern with lengthening survival

1979 • 478 citations

A randomized combined modality trial in small cell carcinoma of the lung comparison of combination chemotherapy-radiation therapy versus cyclophosphamide-radiation therapy effects of maintenance chemotherapy and prophylactic whole brain irradiation

1980 • 210 citations

Randomized trial of radiotherapy to the thorax in limited small-cell carcinoma of the lung treated with multiagent chemotherapy and elective brain irradiation: a preliminary report.

1984 • 206 citations

Neurologic, neuropsychologic, and computed cranial tomography scan abnormalities in 2- to 10-year survivors of small-cell lung cancer.

1985 • 194 citations

Prophylactic Cranial Irradiation in Small Cell Carcinoma of the Lung

1977 • 154 citations

Advances in small cell bronchogenic carcinoma.

1977 • 154 citations

Intracranial metastases in small cell carcinoma of the lung. Correlation of clinical and autopsy findings

1982 • 133 citations

Combination chemotherapy for small cell carcinoma of the lung: continuous versus alternating non-cross-resistant combinations.

1982 • 131 citations

Role of prophylactic cranial irradiation in prevention of central nervous system metastases in small cell lung cancer

1983 • 126 citations

Central nervous system metastases in small cell bronchogenic carcinoma.

1978 • 126 citations

Cisplatin plus etoposide consolidation following cyclophosphamide, doxorubicin, and vincristine in limited small-cell lung cancer.

1988 • 125 citations

Long-term results in combined-modality treatment of small cell carcinoma of the lung.

1978 • 112 citations

The effect of photon irradiation on blood-brain barrier permeability to methotrexate in mice

1977 • 110 citations

Follow-up neurological evaluation in patients with small cell lung carcinoma treated with prophylactic cranial irradiation and chemotherapy

1981 • 109 citations

Role of radiation therapy in small cell anaplastic carcinoma of the lung.

1983 • 107 citations

SMALL-CELL CARCINOMA OF THE LUNG: ATTEMPT TO REMEDY CAUSES OF PAST THERAPEUTIC FAILURE

1976 • 106 citations

Small cell lung cancer: progress and perspectives.

1978 • 96 citations

Low dose elective brain irradiation in small cell carcinoma of the lung

1979 • 93 citations

Comparison of symptomatic and prophylactic irradiation of brain metastases from oat cell carcinoma of the lung

1981 • 86 citations

Intracranial metastases in small cell carcinoma of the lung prognostic aspects

1983 • 84 citations

Long-term survival and toxicity in small cell lung cancer

1984 • 72 citations

Morbidity of cranial relapse in small cell lung cancer and the impact of radiation therapy

1987 • 56 citations

Morbidity in long-term survivors of small cell carcinoma of the lung

1984 • 56 citations

Combined modality treatment of regional small cell unidifferentiated carcinoma of the lung: A cooperative study of the RTOG and ECOG

1983 • 48 citations

Delayed leukoencephalopathy in survivors with small cell lung cancer

1987 • 45 citations

Influence of chest radiotherapy in frequency and patterns of chest relapse in disseminated small cell lung carcinoma. A Southwest oncology group study

1982 • 36 citations

High-dose methotrexate in small cell lung cancer: Lack of efficacy in preventing CNS relapse

1983 • 28 citations

Development of Brain Metastases in Small-Cell Anaplastic Carcinoma of the Lung

1979 • 25 citations