Activation of the Nitric Oxide Synthase 2 Pathway in the Response of Bone Marrow Stromal Cells to High Doses of Ionizing Radiation

A simple technique for quantitation of low levels of DNA damage in individual cells

1988 • 10,537 citations

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1996 • 5,498 citations

Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

1998 • 1,566 citations

Detection and Imaging of Nitric Oxide with Novel Fluorescent Indicators: Diaminofluoresceins

1998 • 1,348 citations

DNA damage and mutation in human cells exposed to nitric oxide in vitro.

1992 • 980 citations

Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress

1997 • 803 citations

The multifaceted roles of nitric oxide in cancer

1998 • 686 citations

Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

1993 • 623 citations

Intercellular Communication Is Involved in the Bystander Regulation of Gene Expression in Human Cells Exposed to Very Low Fluences of Alpha Particles

1998 • 509 citations

A Molecular Redox Switch on p21

1997 • 488 citations

Nitric oxide and its role in apoptosis

1998 • 444 citations

Nitric Oxide Inhibits Caspase-3 by S-Nitrosationin Vivo

1999 • 427 citations

Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages

1991 • 280 citations

Unexpected Sensitivity to the Induction of Mutations by Very Low Doses of Alpha-Particle Radiation: Evidence for a Bystander Effect

1999 • 265 citations

Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression

1997 • 234 citations

The role of nitric oxide (NO·) in the carcinogenic process

1996 • 225 citations

Chapter 42 Fluorescent Cell Labeling for in Vivo and in Vitro Cell Tracking

1990 • 220 citations

Substitution of Chloroform by Bromochloropropane in the Single-Step Method of RNA Isolation

1995 • 204 citations

A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis

1997 • 171 citations

Nitric Oxide Fully Protects against UVA-induced Apoptosis in Tight Correlation with Bcl-2 Up-regulation

1999 • 165 citations

NF-κB and AP-1 Activation by Nitric Oxide Attenuated Apoptotic Cell Death in RAW 264.7 Macrophages

1999 • 157 citations

Suppression of neuronal apoptosis by S-nitrosylation of caspases

1997 • 153 citations

Chromosome Damage Induced by Plasma of X-Rayed Patients: An Indirect Effect of X-Ray

1968 • 152 citations

Mechanisms of the anti-inflammatory activity of low-dose radiation therapy

1998 • 144 citations

Role of nitric oxide in genotoxicity: implication for carcinogenesis.

1998 • 133 citations

Inactivation of zinc finger transcription factors provides a mechanism for a gene regulatory role of nitric oxide

2000 • 118 citations

Autocrine Nitric Oxide Modulates CD95-induced Apoptosis in γδ T Lymphocytes

1997 • 111 citations

Secondary malignancies after bone marrow transplantation in adults.

1994 • 109 citations

Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells

1998 • 80 citations

Nitric Oxide Prevents Oxidative Damage Produced bytert-Butyl Hydroperoxide in Erythroleukemia Cells via Nitrosylation of Heme and Non-heme Iron

1997 • 75 citations

Involvement of Fcε:RII/CD23 and L-argininedependent pathway in IgE-mediated stimulation of human monocyte functions

1994 • 68 citations

Detection of Thiyl Radical Adducts Formed during Hydroxyl Radical- and Peroxynitrite-Mediated Oxidation of Thiols—A High Resolution ESR Spin-Trapping Study at Q-band (35 GHz)

1996 • 67 citations

Induction by staurosporine of nitric oxide synthase expression in vascular smooth muscle cells: role of NF‐κB, CREB and C/EBPβ

1997 • 55 citations

Significant Correlation of Nitric Oxide Synthase Activity and p53 Gene Mutation in Stage I Lung Adenocarcinoma

1998 • 52 citations

Detection and Characterization of the Electron Paramagnetic Resonance-Silent Glutathionyl-5,5-dimethyl-1-pyrrolineN-Oxide Adduct Derived from Redox Cycling of Phenoxyl Radicals in Model Systems and HL-60 Cells

1996 • 48 citations

Long-term results of bone marrow transplantation for patients with AML, ALL and CML prepared with single dose total body irradiation of 500 cGy delivered with a high dose rate.

1991 • 47 citations

Induction of Nitric Oxide Synthase in Subsets of Murine Pulmonary Fibroblasts: Effect on Fibroblast Interleukin-6 Production

1994 • 45 citations

Ionizing radiation potentiates the induction of nitric oxide synthase by IFN-γ and/or LPS in murine macrophage cell lines: role of TNF-α

1998 • 43 citations

Mechanisms of Interleukin-1β Regulation of Nitric Oxide Synthase in Cardiac Myocytes

1996 • 43 citations

Identification of inducible nitric oxide synthase in human macrophages surrounding loosened hip prostheses.

1997 • 42 citations

Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats

1997 • 42 citations

Misincorporation of 2‘-Deoxyoxanosine 5‘-Triphosphate by DNA Polymerases and Its Implication for Mutagenesis

1998 • 41 citations

Effects of irradiation of CBA/CA mice on hematopoietic stem cells and stromal cells in long-term bone marrow cultures.

1996 • 37 citations

Role of Bone Marrow Stromal Cells in Irradiation Leukemogenesis

1996 • 37 citations

Cytokine and Low-Level Nitric Oxide Prestimulation Block p53 Accumulation and Apoptosis of Raw 264.7 Macrophages

1996 • 37 citations

Persistent production of colony‐stimulating factor (CSF‐1) by cloned bone marrow stromal cell line D2XRII after X‐irradiation

1986 • 32 citations

Effects of irradiation of recipient mice on the behavior and leukemogenic potential of factor-dependent hematopoietic cell lines

1990 • 30 citations

Alteration in hematopoietic stem cell seeding and proliferation by both high and low dose rate irradiation of bone marrow stromal cells in vitro

1988 • 25 citations

Involvement of the bone marrow stroma in the residual hematopoietic damage induced by irradiation of adult and young mice.

1994 • 25 citations

Expression of CD23 by human bone marrow stromal cells.

1992 • 21 citations

Ionizing radiation at low doses induces inflammatory reactions in human blood.

1991 • 20 citations

Ionizing Radiation at Low Doses Induces Inflammatory Reactions in Human Blood

1991 • 16 citations

Acquired monosomy 7 in donor cells in a patient treated for acute lymphoblastic leukemia with bone marrow transplantation

1997 • 15 citations

Nitric oxide in human haematopoiesis

1995 • 13 citations

Hematopoietic stem cell- and marrow stromal cell-specific requirements for gamma irradiation leukemogenesis in vitro.

1990 • 12 citations

Cloning and expression of unique murine macrophage colony-stimulating factor transcripts

1995 • 6 citations

Nitric oxide participates in early events associated with NNMU-induced acute lung injury in rats

1999 • 6 citations

The role of intracisternal A-type particles in the evolution of factor-independent murine hematopoietic cell lines

1998 • 5 citations