Increase of cGMP, cADP-ribose and inositol 1,4,5-trisphosphate preceding Ca2+ transients in fertilization of sea urchin eggs

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

Calcium signaling

1995 • 1,905 citations

Comparative Biology of Calcium Signaling during Fertilization and Egg Activation in Animals

1999 • 692 citations

Ca ²⁺ -Induced Ca ²⁺ Release in Sea Urchin Egg Homogenates: Modulation by Cyclic ADP-Ribose

1991 • 628 citations

Essential Role of the Inositol 1,4,5-Trisphosphate Receptor/Ca2+ Release Channel in Ca2+ Waves and Ca2+ Oscillations at Fertilization of Mammalian Eggs

1993 • 521 citations

Cyclic ADP-Ribose in Insulin Secretion from Pancreatic βCells

1993 • 447 citations

Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin.

1988 • 427 citations

cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis

1993 • 337 citations

Lighting the fuse at fertilization

1993 • 328 citations

Inositol 1,4,5-trisphosphate microinjection activates sea urchin eggs

1984 • 316 citations

Redundant Mechanisms of Calcium-Induced Calcium Release Underlying Calcium Waves During Fertilization of Sea Urchin Eggs

1993 • 313 citations

Sources of calcium in egg activation: A review and hypothesis

1983 • 309 citations

Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose

1999 • 308 citations

Calcium Mobilization by Dual Receptors During Fertilization of Sea Urchin Eggs

1993 • 296 citations

The part played by inositol trisphosphate and calcium in the propagation of the fertilization wave in sea urchin eggs.

1986 • 253 citations

Nitric Oxide-induced Mobilization of Intracellular Calcium via the Cyclic ADP-ribose Signaling Pathway

1996 • 230 citations

Isolation, detection and measure of microgram quantities of labeled tissue nucleotides

1959 • 193 citations

Comparison of Ca2+ mobilizing activities of cyclic ADP-ribose and inositol trisphosphate.

1990 • 188 citations

A method of microinjection

1974 • 183 citations

A new form of guanylyl cyclase is preferentially expressed in rat kidney

1990 • 178 citations

NO is necessary and sufficient for egg activation at fertilization

2000 • 172 citations

The Role of Calcium Explosions, Waves, and Pulses in Activating Eggs

1985 • 164 citations

Two phases of inositol polyphosphate and diacylglycerol production at fertilisation

1986 • 142 citations

Cyclic GMP mediates the agonist-stimulated increase in plasma membrane calcium entry in the pancreatic acinar cell.

1990 • 138 citations

Cyclic ADP-ribose and Inositol 1,4,5-Trisphosphate as Alternate Second Messengers for Intracellular Ca2+ Mobilization in Normal and Diabetic β-Cells

1998 • 130 citations

The Type 2 Ryanodine Receptor of Neurosecretory PC12 Cells Is Activated by Cyclic ADP-ribose

1996 • 119 citations

Cortical localization of a calcium release channel in sea urchin eggs.

1992 • 118 citations

Sodium-dependent activation of sea urchin spermatozoa by speract and monensin.

1981 • 116 citations

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs

1995 • 114 citations

The existence of inositol 1,4,5-trisphosphate and ryanodine receptors in mature bovine oocytes

1995 • 111 citations

Identification of PLCγ-Dependent and -Independent Events during Fertilization of Sea Urchin Eggs

1999 • 110 citations

Role of phospholipase Cγ at fertilization and during mitosis in sea urchin eggs and embryos

1999 • 98 citations

Accumulation of cyclic ADP‐ribose measured by a specific radioimmunoassay in differentiated human leukemic HL‐60 cells with all‐trans‐retinoic acid

1995 • 75 citations

The Calcium Transient in Sea Urchin Eggs during Fertilization Requires the Production of Inositol 1,4,5-Trisphosphate

1998 • 74 citations

Presence of Inositol 1,4,5-Trisphosphate Receptor, Calreticulin, and Calsequestrin in Eggs of Sea Urchins and Xenopus laevis

1994 • 74 citations

Internal calcium release and activation of sea urchin eggs by cGMP are independent of the phosphoinositide signaling pathway.

1992 • 73 citations

Primary Structure and Differential Gene Expression of Three Membrane Forms of Guanylyl Cyclase Found in the Eye of the TeleostOryzias latipes

1997 • 71 citations

Effect on Sperm-Induced Activation Current and Increase of Cytosolic Ca2+by Agents That Modify the Mobilization of [Ca2+]i

1995 • 70 citations

Polyphosphoinositlde metabolism during the fertilization wave in sea urchin eggs

1992 • 68 citations

Purification and characterization of particulate guanylate cyclase from sea urchin spermatozoa.

1983 • 68 citations

Sperm Increase Inositol 1,4,5-Trisphosphate Mass in Xenopus laevis Eggs Preinjected with Calcium Buffers or Heparin

1994 • 54 citations

The Two Intracellular Ca2+Release Channels, Ryanodine Receptor and Inositol 1,4,5-Trisphosphate Receptor, Play Different Roles during Fertilization in Ascidians

1997 • 50 citations

Synergistic Calcium Release in the Sea Urchin Egg by Ryanodine and Cyclic ADP Ribose

1994 • 45 citations

Detection of phospholipase Cγ in sea urchin eggs

1998 • 33 citations

An Early Increase in cGMP Follows Fertilization of Sea Urchin Eggs

1996 • 27 citations

The Cyclic GMP-Mediated Calcium Release Pathway in Sea Urchin Eggs Is Not Required for the Rise in Calcium during Fertilization

1996 • 27 citations

Detection of phospholipase Cgamma in sea urchin eggs

1998 • 21 citations

U73122 Blocked the cGMP-Induced Calcium Release in Sea Urchin Eggs

1998 • 18 citations

Purification and Characterization of Sperm Creatine Kinase and Guanylate Cyclase of the Sea Urchin Hemicentrotus pulcherrimus

1992 • 14 citations