Pathologic Effects of Chemotherapy

Atlas of tumor pathology

1968 • 3,075 citations

— Tumors of the Central Nervous System

2013 • 1,787 citations

Handbook of clinical neurology

1975 • 1,642 citations

Randomized Comparisons of Radiotherapy and Nitrosoureas for the Treatment of Malignant Glioma after Surgery

1980 • 1,625 citations

METHODS IN CANCER RESEARCH

1969 • 1,197 citations

The Structure and Function of Nervous Tissue

1972 • 905 citations

Handbook of Clinical Neurology

1979 • 894 citations

PROGRESSIVE MULTIFOCAL LEUKO-ENCEPHALOPATHY

1958 • 831 citations

The Anthracycline Antineoplastic Drugs

1981 • 794 citations

Cisplatin : current status and new developments

1980 • 746 citations

Methotrexate: Distribution in Cerebrospinal Fluid after Intravenous, Ventricular and Lumbar Injections

1975 • 676 citations

Primary osteogenic sarcoma. The rationale for preoperative chemotherapy and delayed surgery

1979 • 588 citations

The central nervous system in childhood leukemia.II. Subacute leukoencephalopathy

1975 • 484 citations

Neurotoxicity of Commonly Used Antineoplastic Agents

1974 • 403 citations

Disseminated necrotizing leukoencephalopathy: A complication of treated central nervous system leukemia and lymphoma

1975 • 391 citations

EFFECTS OF MITOTIC SPINDLE INHIBITORS ON NEUROTUBULES AND NEUROFILAMENTS IN ANTERIOR HORN CELLS

1968 • 379 citations

NEW METHOD FOR MEASURING MILK INTAKES IN BREAST-FED BABIES

1979 • 353 citations

Neurotoxicity and Elevated Cerebrospinal-Fluid Methotrexate Concentration in Meningeal Leukemia

1973 • 341 citations

Toxoplasmosis in the Compromised Host

1976 • 339 citations

The morphologic effects of radiation administered therapeutically for intracranial gliomas.A Postmortem study of 25 cases

1979 • 319 citations

Methods in Cancer Research

1979 • 318 citations

Vincristine‐induced neuropathy

1969 • 300 citations

An electron‐microscope study of the mode of cell death induced by cancer‐chemotherapeutic agents in populations of proliferating normal and neoplastic cells

1975 • 300 citations

Abnormal CT Scans of the Brain in Asymptomatic Children with Acute Lymphocytic Leukemia after Prophylactic Treatment of the Central Nervous System with Radiation and Intrathecal Chemotherapy

1978 • 297 citations

VINCRISTINE NEUROPATHY

1973 • 290 citations

Cancer chemotherapy handbook

1980 • 283 citations

Neurologic sequelae of methotrexate and ionizing radiation: a new classification.

1981 • 271 citations

The neuromyopathy of vincristine in man

1970 • 261 citations

Quantification of combined radiation therapy and chemotherapy effects on critical normal tissues

1976 • 253 citations

Lead in dringking water.

1967 • 219 citations

Prevention of central nervous system leukemia by irradiation

1973 • 215 citations

Vincristine Neurotoxicity

1974 • 210 citations

Central nervous system toxicity of high-dose systemic cytosine arabinoside

1981 • 204 citations

NEURONAL CHANGES INDUCED BY INTRATHECAL VINCRISTINE SULFATE

1968 • 203 citations

Intellectual abilities among survivors of childhood leukaemia as a function of CNS irradiation.

1978 • 197 citations

Chemotherapy of Brain Tumors

1977 • 196 citations

Somnolence after Prophylactic Cranial Irradiation in Children with Acute Lymphoblastic Leukaemia

1973 • 196 citations

The central nervous system in childhood leukemia. I

1973 • 195 citations

Prediction of BCNU Pulmonary Toxicity in Patients with Malignant Gliomas

1980 • 189 citations

Necrotizing Encephalopath Following Intraventricular Instillatio of Methotrexate

1973 • 188 citations

Effects of Central-Nervous-System Irradiation on Neuropsychologic Functioning of Children with Acute Lymphocytic Leukemia

1975 • 176 citations

Childhood acute lymphocytic leukemia. Study VIII

1978 • 173 citations

Paraplegia following intrathecal chemotherapy

1972 • 172 citations

Effects of chemotherapy on the central nervous system—A study of parenteral methotrexate in long-term survivors of leukemia and lymphoma in childhood

1976 • 172 citations

The central nervous system in childhood leukemia.III. mineralizing microangiopathy and dystrophic calcification

1978 • 170 citations

Fatalities During Remission of Childhood Leukemia

1972 • 163 citations

Comparison of Two Methods of Preventing Central Nervous System Leukemia

1973 • 160 citations

Immunosuppression and toxoplasmic encephalitis

1975 • 147 citations

The podophyllotoxin derivatives VP16-213 and VM26

1982 • 146 citations

Vincristine neuropathy: an electrophysiological and histological study.

1969 • 145 citations

Paraplegia following intrathecal methotrexate.Report of a case and review of the literature

1976 • 141 citations

Cancer Chemotherapy Handbook

1981 • 141 citations

Pulmonary Toxicity Associated with Bischloroethylnitrosourea (BCNU)

1979 • 140 citations

IRRADIATION, METHOTREXATE TOXICITY, AND THE TREATMENT OF MENINGEAL LEUKÆMIA

1973 • 138 citations

Methotrexate toxicity: Correlation with duration of administration, plasma levels, dose and excretion pattern

1972 • 136 citations

Cancer and the Nervous System

1969 • 130 citations

Radiation Damage to the Nervous System

1981 • 130 citations

Immunodeficiency and the pathogenesis of lymphoma and leukemia.

1978 • 127 citations

Acquired Toxoplasmosis

1975 • 126 citations

Leukoencephalopathy following the administration of methotrexate into the cerebrospinal fluid in the treatment of primary brain tumors

1974 • 125 citations

Seizures and transient cortical blindness associated with cis-platinum (II) diamminedichloride (PDD) therapy in a thirty-year-old man

1980 • 122 citations

Chronic neurologic disturbance in childhood leukemia

1976 • 115 citations

Adrenergic hyperactivity and cardiac abnormality in primary disorders of sleep

1980 • 114 citations

The effect of photon irradiation on blood-brain barrier permeability to methotrexate in mice

1977 • 110 citations

Necropsy findings in childhood leukaemia, emphasizing neutropenic enterocolitis and cerebral calcification

1976 • 109 citations

Clinical Investigations in the Treatment of Meningeal Leukemia: Radiation Therapy Regimens vs. Conventional Intrathecal Methotrexate

1969 • 108 citations

The central nervous system in acute leukemia: a postmortem study of 117 consecutive cases, with particular reference to hemorrhages, leukemic infiltrations, and the syndrome of meningeal leukemia.

1960 • 107 citations

Clinical Pharmacology of Antineoplastic Drugs

1979 • 107 citations

Involvement of the central nervous system in malignant lymphomas

1976 • 103 citations

Acute Measles Encephalitis in Children With Immunosuppression

1977 • 103 citations

A Phase III comparison of BCNU, hydroxyurea, and radiation therapy to BCNU and radiation therapy for treatment of primary malignant gliomas

1979 • 102 citations

Chronic Renal Failure in Children Treated with Methyl CCNU

1979 • 99 citations

Neurotoxicities of current leukemia therapy.

1979 • 98 citations

The effects of cancer therapy on the nervous system

1978 • 98 citations

Fatal measles infection in children with leukemia.

1973 • 95 citations

Central nervous system lesions in childhood leukemia

1978 • 95 citations

Paraplegia following intrathecal methotrexate

1973 • 94 citations

Parenchymatous degeneration of the central nervous system in childhood leukemia

1974 • 93 citations

Intracerebral calcifications appearing during the course of acute lymphocytic leukemia treated with methotrexate and X rays

1975 • 92 citations

Glioblastoma multiforme: Morphology and biology

1978 • 88 citations

Controlled study of CCNU and radiation therapy in malignant astrocytoma

1976 • 88 citations

Long‐term neurological implications of somnolence syndrome in children with acute lymphocytic leukemia

1980 • 86 citations

Intracranial calcifications in childhood leukemia

1977 • 86 citations

Combination clinical trials with thymidine and fluorouracil: A phase I and clinical pharmacologic evaluation

1980 • 85 citations

[Progressive multifocal leukoencephalopathy and multiple gliomas].

1974 • 80 citations

Herpes simplex encephalitis in an anergic patient

1973 • 80 citations

Five years after central nervous system irradiation of children with leukemia

1976 • 77 citations

Combination chemotherapy and radiation therapy in the treatment of metastatic osteogenic sarcoma

1975 • 76 citations

Long Term Survival among Patients with Malignant Brain Tumors

1982 • 75 citations

VINCRISTINE-INDUCED AXONAL ALTERATIONS IN RAT PERIPHERAL NERVE

1971 • 73 citations

Gemistocytic Astrocytes in Gliomas

1975 • 73 citations

Methotrexate and central nervous system toxicity.

1978 • 72 citations

Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphocytic leukemia

1981 • 71 citations

Axonal transport disturbances in the vincristine-induced peripheral neuropathy.

1975 • 71 citations

Polyneuropathy and Folate Deficiency

1978 • 70 citations

Paraparesis following intrathecal cytosine arabinoside.A case report with neuropathologic findings

1977 • 70 citations

DEATH AFTER INTRATHECAL METHOTREXATE

1969 • 68 citations

INTRATHECAL METHOTREXATE

1969 • 68 citations

Transient cerebral dysfunction following chemotherapy for osteogenic sarcoma

1978 • 68 citations

Fatal myeloencephalopathy caused by intrathecal vincristine

1980 • 67 citations

Response of cultured human brain tumors to nitrosoureas: Correlation with clinical data

1981 • 66 citations

Cis-platinum vestibular toxicity

1981 • 66 citations

The neuromyopathy of vincristine in the guinea pig

1970 • 65 citations

High-dose methotrexate with citrovorum factor rescue for the treatment of central nervous system tumors in children.

1977 • 65 citations

Osmotic blood-brain barrier disruption: pharmacodynamic studies in dogs and a clinical phase I trial in patients with malignant brain tumors.

1981 • 64 citations

Computed tomography brain scans in children with acute lymphocytic leukemia receiving methotrexate alone as central nervous system prophylaxis

1980 • 62 citations

Neurotoxicity Due to CNS Therapy for Leukemia

1977 • 62 citations

Atypical measles infections in leukaemic children on immunosuppressive treatment.

1976 • 61 citations

Axonal transport disturbances in vincristine‐induced peripheral neuropathy

1977 • 61 citations

Encephalomyelopathy following intrathecal methotrexate treatment in a child with acute leukemia

1978 • 60 citations

Human cerebral candidosis — A postmortem evaluation of 19 patients

1981 • 59 citations

Three to ten years after cessation of therapy in children with leukemia

1978 • 59 citations

White-Gray Matter Differentiation in Computed Tomography

1977 • 57 citations

Accidental intrathecal administration of vincristine

1978 • 56 citations

Methotrexate encephalopathy

1978 • 54 citations

Brain-tumor therapy

1977 • 53 citations

Encephalopathy following measles infection in children with chronic illness

1976 • 53 citations

Fatal Graft Versus Host Disease Following a Blood Transfusion in a Child with Neuroblastoma

1981 • 52 citations

Multifocal pontine lesions in cancer patients treated with chemotherapy and cns radiotherapy

1978 • 51 citations

Tumors of the central nervous system (atlas of tumor pathology, 2nd series, fascicle 6)

1975 • 50 citations

THE EFFECT OF VINCRISTINE ON SKELETAL MUSCLE IN THE RAT

1972 • 50 citations

CANCER AND CHEMOTHERAPY

1981 • 49 citations

Progressive Multifocal Leukoencephalopathy

1980 • 48 citations

Adjuvant Nitrosourea Therapy for Glioblastoma

1976 • 46 citations

The development of non-Hodgkin's lymphoma following therapy for Hodgkin's disease

1980 • 46 citations

CSF infections complicating the management of neoplastic meningitis. Clinical features and results of therapy.

1982 • 46 citations

CSF Infections Complicating the Management of Neoplastic Meningitis

1982 • 46 citations

Enlargement of subarachnoid spaces and lateral ventricles in pediatric patients undergoing chemotherapy

1978 • 45 citations

Neurological Lesions in Cats Following Cerebrospinal Fluid Manipulation¹*

1957 • 45 citations

High incidence of vincristine-induced neuropathy in lymphomas.

1978 • 44 citations

Cerebral calcifications associated with intrathecal methotrexate therapy in acute lymphocytic leukemia

1976 • 42 citations

CEREBRAL CALCIFICATION IN CHILDHOOD LEUKEMIA MIMICKING STURGE-WEBER SYNDROME

1974 • 42 citations

Neurological complications of childhood leukaemia.

1977 • 42 citations

Absence of neurotoxicity following massive intrathecal administration of methotrexate.Case report

1967 • 42 citations

Seizures: A significant side effect of chlorambucil therapy in children

1978 • 42 citations

Leukoencephalopathy in childhood leukemia

1977 • 41 citations

METHOTREXATE MENINGITIS

1972 • 40 citations

Atypical progressive multifocal leukoencephalopathy and primary cerebral malignant lymphoma

1978 • 40 citations

Subacute measles encephalitis complicating Hodgkin's disease in an adult

1977 • 40 citations

INTRATHECAL METHOTREXATE

1970 • 39 citations

POSTIRRADIATION SYNDROME AND EEG FINDINGS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKAEMIA

1975 • 38 citations

Neurologic Infections In Children.

1976 • 38 citations

Intrathecal methotrexate overdose without neurotoxicity.Case report and literature review

1978 • 38 citations

Histological observations on the regrowth of malignant gliomas after radiotherapy and chemotherapy

1982 • 37 citations

Leukoencephalopathyfollowing chemotherapy for rhabdomyosarcoma: Reversibility of cerebral changes demonstrated by computed tomography

1977 • 37 citations

Cerebral necrosis following irradiation and chemotherapy for metastatic choriocarcinoma.

1977 • 37 citations

Acute and late effects of multimodal therapy on normal tissues

1977 • 36 citations

Central and peripheral myelinopathy associated with systemic neoplasia and chemotherapy

1981 • 36 citations

ACUTE ENCEPHALOPATHY AFTER INITIATION OF CRANIAL IRRADIATION FOR MENINGEAL LEUKÆMIA

1978 • 36 citations

Central Pontine Myelinolysis in a Child With Leukemia

1966 • 35 citations

Morphological changes in anaplastic gliomas treated with radiation and chemotherapy

1977 • 35 citations

INTRATHECAL METHOTREXATE

1971 • 35 citations

Central pontine myelinolysis in childhood and adolescence.

1969 • 35 citations

Chronic methotrexate toxicity to the central nervous system.

1980 • 33 citations

Measles inclusion-body encephalitis in a child with treated acute lymphoblastic leukaemia.

1976 • 33 citations

Progressive multifocal leukoencephalopathy and malignant lymphoma of the brain in a patient with immunosuppressive therapy

1980 • 33 citations

Neurotoxicity of cis-platinum: Pathology of the central and peripheral nervous systems

1980 • 32 citations

Wernicke's Encephalopathy in Patients With Tumors of the Lymphoid-Hemopoietic Systems

1980 • 32 citations

Acute leukemia complicating treatment of glioblastoma multiforme

1978 • 31 citations

Cerebral lymphomatoid granulomatosis

1976 • 31 citations

Role of infection in the death of children with acute lymphoblastic leukaemia.

1977 • 31 citations

Glioblastoma multiforme in a patient with acute lymphoblastic leukemia who received a marrow transplant.

1982 • 31 citations

Fatal Graft-versus-Host reaction following granulocyte transfusions

1982 • 30 citations

Clinical pharmacology of anti-neoplastic drugs

1978 • 30 citations

Necrotizing myelopathy associated with acute lymphoblastic leukemia

1980 • 30 citations

Cardiotoxic effects of antitumor agents

1978 • 30 citations

Cancer and the nervous system

2001 • 30 citations

Central Pontine Myelinolysis in Childhood

1971 • 29 citations

Morphologic changes associated with combined BCNU and radiation therapy in glioblastoma multiforme

1974 • 29 citations

Kombinierte Strahlen- und Chemotherapie

1979 • 29 citations

Pathology of human malignant gliomas after radiation and chemotherapy

1980 • 26 citations

CT studies before and after CNS treatment for acute lymphoblastic leukemia and malignant non-Hodgkin's lymphoma in childhood

1980 • 26 citations

Vincristine polyneuropathy in man

1977 • 26 citations

ADRIAMYCIN IN ADVANCED BREAST CANCER

1976 • 25 citations

ATYPICAL MEASLES ENCEPHALITIS IN LEUKÆMIC CHILDREN IN REMISSION

1976 • 25 citations

Transient, Severe Periventricular Hypodensity After Leukemic Prophylaxis with Cranial Irradiation and Intrathecal Methotrexate

1978 • 24 citations

Enhancement of the white matter following prophylactic therapy of the central nervous system for leukemia: radiation effects and methotrexate leukoencephalopathy.

1981 • 24 citations

Late Side Effects of Treatment: Skeletal, Genetic, Central Nervous System, and Oncogenic

1976 • 24 citations

Response of cultured human glioblastomas to radiation and BCNU chemotherapy

1974 • 23 citations

Presence of lymphocyte membrane surface markers on “small cells” in a pineal germinoma

1979 • 23 citations

[Graft versus host disease, a little known complication of blood transfusion].

1976 • 22 citations

Neurologic infections in children

1982 • 21 citations

THERAPY OF ACUTE LYMPHOBLASTIC LEUKAEMIA IN CHILDHOOD: EFFECTS ON THE NERVOUS SYSTEM¹

1980 • 21 citations

DISSEMINATED NECROTIZING LEUKOENCEPHALOPATHY

1980 • 21 citations

Malignant gliomas treated after surgery by combination chemotherapy and delayed irradiation

1979 • 21 citations

Late results of multimodality therapy of high-grade supratentorial astrocytomas

1981 • 21 citations

Human central nervous system lesions following radiation therapy.

1977 • 20 citations

Thiamine deficiency: probable Wernicke's encephalopathy successfully treated in a child with acute lymphocytic leukemia.

1973 • 19 citations

Biochemical basis of the acute cerebellar syndrome in 5-fluorouracil chemotherapy.

1969 • 19 citations

Fatal measles encephalopathy with retinopathy during cytotoxic chemotherapy

1977 • 18 citations

SSPE-Like Inclusion Body Disorder in Treated Childhood Leukemia

1975 • 18 citations

Encephalitis due to simultaneous infection by herpes simplex and measles viruses

1971 • 17 citations

Vincristine toxicity unrelated to dose.

1976 • 17 citations

Review of selected experimental brain tumor models used in chemotherapy experiments.

1975 • 16 citations

Cerebral space-occupying cysts following radiation and chemotherapy of malignant gliomas

1981 • 16 citations

IMMUNOSUPPRESSIVE MEASLES ENCEPHALOPATHY

1978 • 15 citations

Cranial computed tomography in leukaemia

1978 • 15 citations

Vindesine a clinical trial with special reference to neurological side effects

1979 • 15 citations

An Analysis of the Interaction between Two Nitrosourea Compounds and X-radiation in Rat Brain Tumour Cells

1980 • 15 citations

Malignant gliomas treated after surgery by combination chemotherapy and delayed radiation therapy

1979 • 14 citations

Acute ascending poliomyelomalacia after treatment of acute lymphocytic leukemia

1979 • 14 citations

Neurological Complications in Clinical Haematology

1981 • 14 citations

Unusual Encephalitic Illnesses in a Child with Acute Leukaemia in Remission: Possible Role of Measles Virus and Toxoplasma Gondii

1976 • 14 citations

Intermittent meningitic reaction with severe basophilia and eosinophilia in CNS leukaemia

1976 • 14 citations

Chemotherapy of nonirradiated malignant gliomas.Phase II: Study of the combination of methyl-CCNU, vincristine, and procarbazine

1979 • 14 citations

Computerized axial tomography in the study of intracranial complications in hematology

1978 • 13 citations

Combined cyclotron fast-neutron and BCNU therapy in a rat brain-tumor model

1981 • 13 citations

Multifocal leukoencephalopathy in adult leukemia: Histologic features and etiologic considerations

1977 • 13 citations

Thiamine Deficiency: Probable Wernicke's Encephalopathy Successfully Treated in a Child With Acute Lymphocytic Leukemia

1973 • 13 citations

Human Malignant Gliomas Treated with Chemotherapy

1978 • 13 citations

Combination chemotherapy of malignant glioma. Effect of postoperative treatment with CCNU, vincristine, amethopterine and procarbazine

1978 • 13 citations

Prospective Neuropathologic Study on the Occurrence of Wernicke’s Encephalopathy in Patients With Tumours of the Lymphoid-Hemopoietic Systems

1981 • 12 citations

Brain calcification in a case of acute lymphoblastic leukaemia

1975 • 12 citations

Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU

1976 • 12 citations

Infantile cortical measles inclusion body encephalitis during combined treatment of acute lymphoblastic leukemia

1979 • 12 citations

Basophilic meningitis secondary to lymphoma

1976 • 12 citations

Encephalitis due to herpes simplex in a patient with treated carcinoma of the uterus

1967 • 11 citations

Ein licht- und elektronenoptischer Beitrag zur Vinca-Alkaloid-Polyneuropathie

1972 • 10 citations

Analysis of the effects of antitumor drugs on cell cycle kinetics.

1975 • 10 citations

Neurological complications in clinical haematology

1980 • 9 citations

Communicating Hydrocephalus in Treated Leukemic Patients

1979 • 9 citations

Findings in Computerized Axial Tomography after Intrathecal Methotrexate and Radiation

1978 • 8 citations

Neuropathologic Effects of Intrathecal Water

1975 • 8 citations

A possible neurologic complication of DTIC.

1977 • 8 citations

Normal computed tomograms of the brain in osteosarcoma patients treated with high-dose methotrexate

1981 • 8 citations

Findings in computerized axial tomography after intrathecal methotrexate and radiation

1978 • 7 citations

Auffällige CT-Befunde des Schädels nach präventiver ZNS-Behandlung akuter Leukämien bei Kindern

1979 • 7 citations

Exacerbation of Myotonia Dystrophica by Vincristine

1976 • 6 citations

Symptomatic hypophosphatemia secondary to 5-azacytidine therapy of acute nonlymphocytic leukemia.

1976 • 6 citations

Iatrogenic Damage to the Central Nervous System in Malignant Systemic Disease

1981 • 6 citations

Multimodality treatment of malignant gliomas. Comparison of several adjuvant approaches.

1981 • 4 citations

Central Nervous System Toxicities from Combined Therapies

2015 • 4 citations

Submicroscopic changes in leukaemia cells of the cerebrospinal fluid following intrathecal methotrexate

1974 • 3 citations

[Intrathecal application of antineoplastic agents (author's transl)].

1978 • 3 citations

Complications of cytostatic therapy in childhood leukemia.

1973 • 3 citations

Acute necrotizing encephalitis in a patient with Hodgkin's disease. A case report.

1971 • 3 citations

Autobiography of a Physiologist--II

1971 • 3 citations

Micronodular Encephalitis and Acute Leukemia Treated with Immunosuppressives in a Child

1975 • 2 citations

Encephalopathie apparue au cours d'un traitement par la vincristine. Observation anatomo-clinique

1974 • 1 citations