Heterozygosity for HLA-Linked Hemochromatosis as a Likely Cause of the Hepatic Siderosis Associated With Sporadic Porphyria Cutanea Tarda

An inherited enzymatic defect in porphyria cutanea tarda: decreased uroporphyrinogen decarboxylase activity.

1976 • 283 citations

DEANOL IN SPONTANEOUS AND INDUCED DYSKINESIAS

1975 • 254 citations

Decreased Activity of Hepatic Uroporphyrinogen Decarboxylase in Sporadic Porphyria Cutanea Tarda

1978 • 204 citations

Familial and sporadic porphyria cutanea

1978 • 181 citations

Hereditary Hemochromatosis: Analysis of Laboratory Expression of the Disease by Genotype in 18 Pedigrees

1982 • 181 citations

Hereditary Hemochromatosis

1977 • 141 citations

Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III.

1983 • 138 citations

The role of iron in the pathogenesis of porphyria cutanea tarda. II. Inhibition of uroporphyrinogen decarboxylase.

1975 • 132 citations

Iron Deficiency Prevents Liver Toxicity of 2,3,7,8-Tetrachlorodibenzo- p -Dioxin

1979 • 110 citations

Prevalence of Iron Overload in Central Sweden

1983 • 110 citations

Measuring the genetic contribution of a single locus to a multilocus disease

1984 • 108 citations

IRON STORAGE IN PORPHYRIA CUTANEA TARDA

1970 • 107 citations

Hereditary Haemochromatosis

1982 • 105 citations

Hemochromatosis: Genetic or alcohol-induced?

1983 • 105 citations

Porphyria Cutanea Tarda in Three Generations of a Single Family

1978 • 90 citations

Decreased Hepatic Uroporphyrinogen Decarboxylase Activity in Porphyria Cutanea Tarda

1982 • 82 citations

HLA typing in idiopathic hemochromatosis: Distinction between homozygotes and heterozygotes with biochemical expression

1981 • 81 citations

The Treatment of Porphyria Cutanea Tarda by Venesection

1974 • 78 citations

Idiopathic Hemochromatosis and Iron Overload in Alcoholic Liver Disease: Differentiation by HLA Phenotype

1977 • 78 citations

Dual mechanism of inhibition of rat liver uroporphyrinogen decarboxylase activity by ferrous iron: Its potential role in the genesis of porphyria cutanea tarda

1984 • 77 citations

The genetics of hemochromatosis.

1980 • 77 citations

Treatment of porphyria cutanea tarda by phlebotomy.

1977 • 75 citations

Purification and characterization of bovine hepatic uroporphyrinogen decarboxylase

1983 • 75 citations

Hereditary hemochromatosis: contributions of genetic analyses.

1981 • 70 citations

Enzymatic and immunological studies of uroporphyrinogen decarboxylase in familial porphyria cutanea tarda and hepatoerythropoietic porphyria.

1984 • 68 citations

Identification of Two Types of Porphyria Cutanea Tarda by Measurement of Erythrocyte Uroporphyrinogen Decarboxylase

1980 • 67 citations

Iron Metabolism in Porphyria Cutanea Tarda and in Erythropoietic Protoporphyria

1973 • 66 citations

THE EFFECT OF REPLENISHMENT OF IRON STORES AFTER PHLEBOTOMY THERAPY IN PORPHYRIA CUTANEA TARDA

1971 • 66 citations

Acute ethanol ingestion and haem biosnthesis in health subjects

1980 • 64 citations

Idiopathic hemochromatosis: A study of biochemical expression in 247 heterozygous members of 63 families: Evidence for a single major HLA-linked gene

1980 • 59 citations

Red-Cell Uroporphyrinogen Decarboxylase Activity in Porphyria Cutanea Tarda and in Other Forms of Porphyria

1978 • 58 citations

Abnormal haem biosynthesis in chronic alcoholics

1981 • 52 citations

Studies on the action of porphyrinogenic trace metals on the activity of hepatic uroporphyrinogen decarboxylase

1981 • 43 citations

IMMUNOREACTIVE UROPORPHYRINOGEN DECARBOXYLASE IN PORPHYRIA CUTANEA TARDA

1983 • 42 citations

THE HISTOPATHOLOGY OF THE LIVER IN ACQUIRED (SYMPTOMATIC) PORPHYRIA.

1963 • 42 citations

Iron and Hepatic Uroporphyrin Synthesis

1973 • 36 citations

Alcohol-Induced Decrease in Uroporphyrinogen Decarboxylase Activity in Rat Liver and Spleen

1981 • 33 citations

Porphyrin Metabolism in Experimental Hepatic Siderosis in the Rat

1972 • 33 citations

Porphyria cutanea tarda-a genetic disease? A biochemical and fluorescence microscopical study in four families.

1973 • 30 citations

Uroporphyrinogen decarboxylase. A method for measuring enzyme activity.

1982 • 28 citations

Purification and properties of human erythrocyte uroporphyrinogen decarboxylase: immunological demonstration of the enzyme defect in porphyria cutanea tarda.

1983 • 25 citations

Uroporphyrinogen Decarboxylase

1982 • 23 citations

PORPHYRIA CUTANEA TARDA—A GENETIC DISEASE?

1973 • 22 citations

HLA and porphyria cutanea tarda

1980 • 22 citations

High-performance liquid chromatography of porphyrin esters

1981 • 21 citations

Iron Metabolism in Porphyria Cutanea Tarda

1975 • 18 citations

[Porphyrins and idiopathic hemochromatosis. Study of 32 cases (author's transl)].

1978 • 3 citations