Demonstration by electrospray mass spectrometry that the peptidyldipeptidase activity of cathepsin B is capable of rat cathepsin B C-terminal processing

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Electrospray Ionization for Mass Spectrometry of Large Biomolecules

1989 • 7,324 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

[41] Cathepsin B, cathepsin H, and cathepsin L

1981 • 1,678 citations

New developments in biochemical mass spectrometry: electrospray ionization

1990 • 1,048 citations

Polypeptides of the tail fibres of bacteriophage T4

1971 • 956 citations

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity.

1991 • 595 citations

The determination of protein, oligonucleotide and peptide molecular weights by ion‐spray mass spectrometry

1988 • 592 citations

Human cathepsin B1. Purification and some properties of the enzyme

1973 • 322 citations

Peptide and protein analysis by electrospray ionization-mass spectrometry and capillary electrophoresis-mass spectrometry

1989 • 256 citations

Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs.

1986 • 245 citations

Homology of amino acid sequences of rat liver cathepsins B and H with that of papain.

1983 • 231 citations

Rat procathepsin B. Proteolytic processing to the mature form in vitro.

1992 • 181 citations

The specificity of cathepsin B. Hydrolysis of glucagon at the C-terminus by a peptidyldipeptidase mechanism

1978 • 159 citations

Carboxyl-terminal proteolytic processing during biosynthesis of the lysosomal enzymes .beta.-glucuronidase and cathepsin D

1983 • 95 citations

Degradation of fructose-1,6-bisphosphate aldolase by cathepsin B

1980 • 95 citations

Characterization of recombinant rat cathepsin B and nonglycosylated mutants expressed in yeast. New insights into the pH dependence of cathepsin B-catalyzed hydrolyses.

1992 • 89 citations

Amino acid sequence of human liver cathepsin B

1985 • 82 citations

Identification of cDNA clones encoding a precursor of rat liver cathepsin B.

1985 • 73 citations

Porcine spleen cathepsin B is an exopeptidase.

1986 • 52 citations

Expression of lysosomal cathepsin B during calf myoblast-myotube differentiation. Characterization of a cDNA encoding bovine cathepsin B

1991 • 48 citations

Interaction of lysosomal cysteine proteinases with α2-macroglobulin: Conclusive evidence for the endopeptidase activities of cathepsins B and H

1989 • 41 citations

Chromophoric and fluorophoric peptide substrates cleaved through the dipeptidyl carboxypeptidase activity of cathepsin B

1987 • 38 citations

Comparative studies of two cathepsin B isozymes from porcine spleen. Isolation, polypeptide chain arrangements, and enzyme specificity.

1986 • 33 citations

Crystallization of recombinant rat cathepsin B.

1990 • 20 citations

Disulfide Bridges of Boviae Spleen Cathepsin B

1990 • 13 citations