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Anorexia of aging: physiologic and pathologic

Data up to Jan 2025

Published1997
Citations751
References184
Clinical Trials (1)

Total Citations Per Year

Abstract

References (184)

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

1984 • 1,490 citations

Prognostic nutritional index in gastrointestinal surgery

1980 • 1,374 citations

Precipitating Factors for Delirium in Hospitalized Elderly Persons

1996 • 1,300 citations

Smell Identification Ability: Changes with Age

1984 • 1,295 citations

Perioperative Total Parenteral Nutrition in Surgical Patients

1991 • 1,201 citations

Biological Actions of Androgens

1987 • 1,093 citations

Leptin: The Tale of an Obesity Gene

1996 • 987 citations

Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity

1986 • 856 citations

Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men

1997 • 822 citations

Dietary supplementation in elderly patients with fractured neck of the femur

1990 • 812 citations

Clinical and Metabolic Efficacy of Glutamine-supplemented Parenteral Nutrition after Bone Marrow Transplantation

1992 • 763 citations

Diabetes and Cardiovascular Disease: The “Common Soil” Hypothesis

1995 • 673 citations

Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis

1995 • 604 citations

Neuropeptide Regulation of Appetite and Weight*

1987 • 598 citations

Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation.

1994 • 586 citations

Abdominal obesity as important component of insulin-resistance syndrome.

1993 • 568 citations

Benefits of supplementary tube feeding after fractured neck of femur: a randomised controlled trial.

1983 • 493 citations

Association Between Nutritional Status and Cognitive Functioning in a Healthy Elderly Population

1983 • 480 citations

Effects of Testosterone Replacement Therapy in Old Hypogonadal Males: A Preliminary Study

1993 • 474 citations

Opioid modulation of appetite

1983 • 452 citations

Nutrition and health risks in the elderly: the nutrition screening initiative.

1993 • 448 citations

Control of Food Intake in Older Men

1994 • 396 citations

A Randomized Trial of Isonitrogenous Enteral Diets After Severe Trauma

1996 • 387 citations

Dementia: The Experience of Family Caregivers

1986 • 382 citations

Growth Hormone, Body Composition, and Aging

1985 • 365 citations

Economic Impact of Malnutrition: A Model System for Hospitalized Patients

1988 • 346 citations

Smell and taste in health and disease

1992 • 334 citations

The neuroendocrine control of appetite: The role of the endogenous opiates, cholecystokinin, TRH, gamma-amino-butyric-acid and the diazepam receptor

1980 • 331 citations

Causes of Weight Loss in a Community Nursing Home

1994 • 324 citations

Nutritional Epidemiology

2011 • 320 citations

Secondary Hypogonadism in Older Men: Its Relation to Impotence*

1990 • 318 citations

Effect of dietary supplement on nutritional status and clinical outcome in 501 geriatric patients—a randomised study

1990 • 314 citations

The Dietary Variety Score

1997 • 306 citations

Nutritional Issues in Nursing Home Care

1995 • 306 citations

Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates

1996 • 305 citations

Effect of neuropeptide Y on ingestive behaviors in the rat

1987 • 293 citations

Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults

1997 • 286 citations

Impact of nutritional status on DRG length of stay

1987 • 274 citations

1 Physical Disability in Older Americans

1993 • 273 citations

Behavioral effects of corticotropin-releasing factor: localization and characterization of central effects

1988 • 267 citations

Accelerated improvement of alcoholic liver disease with enteral nutrition

1992 • 263 citations

Olfactory Dysfunction and Related Nutritional Risk in Free-Living, Elderly Women

1995 • 249 citations

The Importance of Dietary Protein in Healing Pressure Ulcers

1993 • 246 citations

Effect of flavor enhancement of foods for the elderly on nutritional status: Food intake, biochemical indices, and anthropometric measures

1993 • 245 citations

Involuntary Weight Loss: Diagnostic and Prognostic Significance

1981 • 232 citations

A controlled trial of cyproheptadine in cancer patients with anorexia and/or cachexia

1990 • 230 citations

Nutritional Status and Dietary Intake in Institutionalized Patients With Alzheimer's Disease and Multiinfarct Dementia

1987 • 218 citations

Effect of age on gastric emptying of liquid-solid meals in man

1983 • 216 citations

A Phase II Study of Delta-9-Tetrahydrocannabinol for Appetite Stimulation in Cancer-Associated Anorexia

1994 • 211 citations

Changes in Gastric Emptying Rates with Age

1984 • 209 citations

Age-related impairments in the regulation of food intake

1995 • 207 citations

Cost Containment Through Nutrition Intervention

2009 • 189 citations

Naloxone, an opiate blocker, reduces the consumption of sweet high-fat foods in obese and lean female binge eaters

1995 • 189 citations

Time course of effects of preloads high in fat or carbohydrate on food intake and hunger ratings in humans

1991 • 188 citations

Social facilitation of the spontaneous meal size of humans occurs regardless of time, place, alcohol or snacks

1990 • 188 citations

Taste and Aging

1986 • 186 citations

Relation between postprandial satiation and antral area in normal subjects

1997 • 184 citations

Effects of age on sensory-specific satiety

1991 • 182 citations

Food Recognition by the Elderly

1977 • 181 citations

Effect of age on bone density and bone turnover in men

1995 • 179 citations

Relationships between Taste and Smell across the Adult Life Spana

1989 • 174 citations

Unexplained Weight Loss in the Ambulatory Elderly

1991 • 173 citations

The Nutrition Implications of Cardiac Cachexia

2009 • 169 citations

The Effects of Bereavement on Eating Behaviors and Nutrient Intakes in Elderly Widowed Persons

1993 • 165 citations

Neuropeptide Y increases food intake in mice

1987 • 161 citations

Protein‐Energy Undernutrition and the Risk of Mortality Within One Year of Hospital Discharge: A Follow‐Up Study

1995 • 155 citations

Social Support, Stressful Events, Strain, Dietary Intake, and the Elderly

1989 • 148 citations

The Effect of Recombinant Human Growth Hormone on Malnourished Older Individuals

1991 • 146 citations

Nutritional Status in an Academic Nursing Home

1988 • 145 citations

Oral Health Problems and Involuntary Weight Loss in a Population of Frail Elderly

1993 • 140 citations

Randomized clinical trial of nutritional supplementation shows little effect on functional status among free-living frail elderly.

1995 • 138 citations

Carpal tunnel syndrome and gynaecomastia during growth hormone treatment of elderly men with low circulating IGF‐I concentrations

1993 • 138 citations

Calorie and Nutrient Intakes of Elderly and Young Subjects Measured Under Identical Conditions

1988 • 133 citations

Taste Sensitivity and Aging: High Incidence of Decline Revealed by Repeated Threshold Measures

1995 • 129 citations

Continuing Diet Trends in Men: The Baltimore Longitudinal Study of Aging (1961-1987)

1990 • 126 citations

Dietary patterns and their associations with demographic, lifestyle and health variables in a random sample of British adults

1996 • 125 citations

Bacterial contamination of the small intestine is an important cause of occult malabsorption in the elderly.

1983 • 119 citations

Regulation of Energy Expenditure in Aging Humans

1993 • 115 citations

Sensory Perception and Pleasantness of Food Flavors in Elderly Subjects

1994 • 114 citations

The effects of aging on opioid modulation of feeding in rats

1983 • 112 citations

Appetite regulation by carbohydrate: role of blood glucose and gastrointestinal hormones

1996 • 109 citations

Polycythemia as a Complication of Testosterone Replacement Therapy in Nursing Home Men with Low Testosterone Levels

1995 • 109 citations

The Role of Nutrition in Increased Morbidity and Mortality

1995 • 107 citations

Major Depression with Melancholia: A Comparison of Middle‐Aged and Elderly Adults

1987 • 107 citations

Modulation of food intake by peripherally administered amylin

1994 • 107 citations

Location and variation in number of taste buds in human fungiform papillae

1979 • 107 citations

Taste Intensity Perception in Aging

1986 • 106 citations

Competitive antagonism of nitric oxide synthetase causes weight loss in mice

1992 • 103 citations

Effect of aging on gallbladder contraction and release of cholecystokinin-33 in humans.

1985 • 102 citations

Intra-abdominal fat: is it a major factor in developing diabetes and coronary artery disease?

1996 • 100 citations

Review article: symptom improvement through eradication of Helicobacter pylori in patients with non‐ulcer dyspepsia

1996 • 99 citations

Effect of Aging on Body Fat

1993 • 98 citations

Consensus of the Nutrition Screening Initiative: Risk factors and indicators of poor nutritional status in older Americans

1991 • 96 citations

Salt Taste Perceptions and Preferences are Unrelated to Sodium Consumption in Healthy Older Adults

1996 • 94 citations

Evidence for a physiological role for CCK in the regulation of food intake in mice

1989 • 93 citations

Influence of age on energy requirements

1995 • 91 citations

Unintentional Weight Loss

1986 • 85 citations

Sensory evaluations of fat-sucrose and fat-salt mixtures: Relationship to age and weight status

1990 • 84 citations

The relation of body weight to length of stay and charges for hospital services for patients undergoing elective surgery: a study of two procedures.

1987 • 83 citations

Clinical Physiology of Taste and Smell

1993 • 83 citations

Distributions of serial changes in stature and weight in a healthy elderly population.

1988 • 82 citations

Hypocholesterolemia As a Predictor of Death: A Prospective Study of 224 Nursing Home Residents

1991 • 81 citations

Formal Geriatric Assessment Instruments and the Care of Older General Medical Outpatients

1990 • 80 citations

Gustatory and olfactory dysfunction in dementia: Not specific to Alzheimer's disease

1990 • 79 citations

Prognostic Significance of Serum Cholesterol in Nursing Home Men

1988 • 78 citations

Nutritional support in hospitalized patients with alcoholic liver disease.

1989 • 77 citations

Induction of Obesity by Psychotropic Drugs

1987 • 77 citations

Mental Depression Is Associated With Malnutrition in Patients With Head and Neck Cancer

1988 • 73 citations

Intake of Energy, Nutrients and Food Items in a Ten-year Cohort Comparison and in a Six-year Longitudinal Perspective: A Population Study of 70- and 76-year-old Swedish People

1994 • 72 citations

On the discrimination of missing ingredients: Aging and salt flavor

1991 • 72 citations

Good Nutritional Oral Intake Is Associated with Equal Survival in Demented and Nondemented Very Old Patients

1996 • 72 citations

Effect of Sucrose in Breakfast Items on Pleasantness and Food Intake in The Elderly

1996 • 71 citations

Geriatric Grand Rounds: Nutrition and the Elderly: University of California, Los Angeles

1986 • 70 citations

The correctability of the nutritional, immune, and hematopoietic manifestations of protein calorie malnutrition in the elderly.

1982 • 70 citations

Inhibition of feeding by a nitric oxide synthase inhibitor: effects of aging

1996 • 68 citations

Role of the Opioid System in the Hypodipsia Associated with Aging

1992 • 67 citations

Age-related differences in the pleasantness of chemosensory stimuli.

1986 • 67 citations

The influence of opiate agonists on day-night feeding rhythms in young and old mice

1985 • 65 citations

Effect of Ageing on the Gastro-Intestinal Transit of a Lactulose-Supplemented Mixed Solid-Liquid Meal in Humans

1988 • 64 citations

Effects of Age on Energy Expenditure and Substrate Oxidation During Experimental Overfeeding in Healthy Men

1996 • 63 citations

A Two-centre, Randomized, Double-blind Trial of Ornithine Oxoglutarate in 194 Elderly, Ambulatory, Convalescent Subjects

1994 • 63 citations

The New Mexico Aging Process Study

2009 • 62 citations

Depression

1989 • 61 citations

A Study of the Nutritional Status of Elderly Patients with Parkinson′s Disease

1994 • 60 citations

Insulin, Neuropeptide Y, and Food Intake

1993 • 60 citations

Measurement of nitric oxide synthase and its mRNA in genetically obese (ob/ob) mice

1995 • 60 citations

Failure To Thrive in the Elderly: Exploration of the Concept and Delineation of Psychiatric Components

1993 • 60 citations

Resting Energy Expenditure in Relation to Energy Intake in Patients with Alzheimer's Disease, Multi-infarct Dementia and in Control Women

1993 • 58 citations

Nutritional Risk in Inner‐City‐Dwelling Older Black Americans

1996 • 57 citations

Anorexia tardive—Late onset marital anorexia nervosa

1984 • 57 citations

Prevalence of obesity in Sweden: cross‐sectional study of a representative adult population

1990 • 57 citations

Abnormal Eating Attitudes and Body Image in Older Undernourished Individuals

1991 • 56 citations

Amylin given by central or peripheral routes decreases gastric emptying and intestinal transit in the rat

1996 • 56 citations

Alterations in plasma and cerebrospinal fluid levels of neuropeptides in idiopathic senile anorexia

1993 • 56 citations

Missing Ingredients

1990 • 56 citations

Sugar, opioids and binge eating

1985 • 55 citations

The Management of Diabetes Mellitus in Older Individuals

1991 • 55 citations

Energy Intake and In-Hospital Starvation

1996 • 55 citations

Racial Differences in Plasma Leptin Concentrations in Obese Postmenopausal Women

1997 • 53 citations

Feeding and drinking responses to neuropeptide Y injections in the paraventricular hypothalamic nucleus of aged rats

1992 • 53 citations

Recognizing Elder Abuse and Neglect

1993 • 51 citations

Sertoli cell function declines earlier than leydig cell function in aging Japanese men

1994 • 49 citations

Postprandial Cholecystokinin Secretion in Elderly with Protein‐Energy Undernutrition

1992 • 48 citations

Idpathic CD4+ T Lymphopenia in Older Persons

1994 • 48 citations

Nutritional assessment of the elderly in the ambulatory care setting.

1994 • 47 citations

Suprathreshold sour taste intensity and pleasantness perception with age

1988 • 44 citations

Elevated postprandial insulin levels do not induce satiety in normal-weight humans

1984 • 44 citations

Opioid Peptides and Aging

1990 • 43 citations

Relationship of age and calcitonin gene-related peptide to postprandial hypotension

1996 • 43 citations

Corticotropin releasing factor (CRF) and age-related differences in behavior of mice

1989 • 42 citations

Aging in women—the four-compartment model of body composition

1996 • 42 citations

Appetite stimulation and weight gain with megestrol acetate.

1990 • 42 citations

Anorexia in older patients: its meaning and management.

1990 • 41 citations

Amylin

1992 • 41 citations

Changes in Taste Sensitivity with Advancing Age

1969 • 40 citations

The Anorexia of the Elderly

1989 • 40 citations

Taste acuity and aging

1982 • 38 citations

Taste and Smell

1992 • 38 citations

Effects of amylin on appetite regulation and memory

1995 • 36 citations

Aggressive oral refeeding in hospitalized patients

1990 • 35 citations

Effects of Acute and Chronic Infusion of Islet Amyloid Polypeptide on Food Intake in Rats

1996 • 34 citations

Management of anorexia-cachexia associated with cancer and HIV infection.

1991 • 33 citations

Effect of aging on plasma cholecystokinin secretion and gallbladder emptying

1988 • 30 citations

Effects of Age on Energy Expenditure and Substrate Oxidation During Experimental Underfeeding in Healthy Men

1996 • 30 citations

Prevalence of depressive and other symptoms in elderly Finnish men

1986 • 29 citations

Innervation in Human Taste Buds and Its Decrease in Alzheimer's Disease Patients

1995 • 29 citations

Effect of Aging on Fluid Ingestion in Mice

1991 • 28 citations

Failure to Thrive in the Elderly

1995 • 27 citations

Death by Starvation

1989 • 26 citations

An approach to nutrition screening for older Americans.

1992 • 26 citations

Age-related changes in amylin secretion

1996 • 25 citations

Interactions among aging, gender, and gonadectomy effects upon naloxone hypophagia in rats

1993 • 24 citations

D‐E‐N‐T‐A‐L: A Rapid Self‐Administered Screening Instrument to Promote Referrals for Further Evaluation in Older Adults

1996 • 24 citations

Weight loss and weight gain in a nursing home: A prospective study

1993 • 23 citations

Helicobacter pylori Infection and Anorexia of Aging

1997 • 22 citations

Effect of cyproheptadine on anorexia and loss of weight in adults.

1972 • 20 citations

Altered cerebrospinal fluid amino acid pattern in the anorexia of aging: Relationship with biogenic amine metabolism

1993 • 18 citations

Primary Hyperparathyroidism and Delirium in The Elderly

1988 • 18 citations

Nutritional Survey of an Elderly Russian Population

1994 • 13 citations

Post-prandial hypotension in the elderly.

1995 • 13 citations

Diagnosis and Treatment of Dyspepsia in the Elderly

1995 • 10 citations

Enteral feeding--problems and solutions.

1994 • 6 citations

Considerations for Those Providing Nutritional Care to the Elderly

1986 • 5 citations

Ornithine Oxoglutarate Therapy Improves Nutrition Status

2009 • 4 citations

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