The Role of the Cell Surface in Contact Inhibition of Cell Division

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Lectins: Cell-Agglutinating and Sugar-Specific Proteins

1972 • 1,716 citations

The locomotion of fibroblasts in culture

1971 • 955 citations

The initiation of cell division in a contact‐inhibited mammalian cell line

1965 • 807 citations

Observations on the social behaviour of cells in tissue culture

1954 • 606 citations

A DIFFERENCE IN THE ARCHITECTURE OF THE SURFACE MEMBRANE OF NORMAL AND VIRALLY TRANSFORMED CELLS

1969 • 549 citations

"Contact inhibition" of cell division in 3T3 cells.

1968 • 547 citations

The Covalent and Three-Dimensional Structure of Concanavalin A

1972 • 533 citations

INTERACTION OF THE CARBOHYDRATE-BINDING PROTEIN CONCANAVALIN A WITH NORMAL AND TRANSFORMED CELLS

1969 • 525 citations

Proteolytic Enzymes Initiating Cell Division and Escape from Contact Inhibition of Growth

1970 • 513 citations

IDENTIFICATION OF A TUMOR-SPECIFIC DETERMINANT ON NEOPLASTIC CELL SURFACES

1967 • 458 citations

Topoinhibition and Serum Requirement of Transformed and Untransformed Cells

1970 • 444 citations

Rous Sarcoma Virus: a Function required for the Maintenance of the Transformed State

1970 • 444 citations

Restoration of Several Morphological Characteristics of Normal Fibroblasts in Sarcoma Cells Treated with Adenosine-3′:5′-Cyclic Monophosphate and Its Derivatives

1971 • 440 citations

Density Dependent Inhibition of Cell Growth in Culture

1967 • 440 citations

MICROFILAMENTS AND CELL LOCOMOTION

1971 • 437 citations

“Pleiotypic Response”

1971 • 415 citations

Difference in the Cyclic Adenosine 3′,5′-Monophosphate Levels in Normal and Transformed Cells

1972 • 396 citations

The locomotion of fibroblasts in culture I. Movements of the leading edge

1970 • 389 citations

Guanosine 3′:5′-Cyclic Monophosphate: A Possible Intracellular Mediator of Mitogenic Influences in Lymphocytes

1972 • 381 citations

The growth of the retina in Xenopus laevis: an autoradiographic study

1971 • 370 citations

Contact inhibition in tissue culture

1970 • 369 citations

Chapter 4 Low-Resistance Junctions Between Cells in Embryos and Tissue Culture

1968 • 349 citations

Restoration of Normal Growth by Covering of Agglutinin Sites on Tumour Cell Surface

1970 • 347 citations

EVIDENCE FOR CELL-SURFACE GLYCOSYLTRANSFERASES

1971 • 339 citations

Release from Density Dependent Growth Inhibition by Proteolytic Enzymes

1970 • 338 citations

Glycolipids of hamster fibroblasts and derived malignant-transformed cell lines.

1968 • 336 citations

Comparative study of glycoproteins from the surface of control and Rous sarcoma virus transformed hamster cells

1970 • 335 citations

Transport of Amino Acids by Confluent and Nonconfluent 3T3 and Polyoma Virus-transformed 3T3 Cells Growing on Glass Cover Slips

1969 • 335 citations

Chemical dissolution and in vitro reconstruction of sponge cell adhesions

1963 • 327 citations

Restoration of Contact-Inhibited Growth to Transformed Cells by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1971 • 321 citations

Regulation of Cell Growth by Cyclic Adenosine 3′,5′-Monophosphate

1972 • 314 citations

Heparan sulfates of cultured cells. I. Membrane-associated and cell-sap species in Chinese hamster cells

1971 • 313 citations

Uptake of Heterologous Genome by Mammalian Spermatozoa and Its Transfer to Ova through Fertilization

1971 • 298 citations

CONTACT INHIBITION, MACROMOLECULAR SYNTHESIS, AND POLYRIBOSOMES IN CULTURED HUMAN DIPLOID FIBROBLASTS

1965 • 298 citations

Growth Control and Cyclic Alterations of Cyclic AMP in the Cell Cycle

1972 • 292 citations

A Unifying Hypothesis Concerning the Nature of Malignant Growth

1972 • 282 citations

Increased Uptake of Amino Acids and 2-Deoxy-D-Glucose by Virus-Transformed Cells in Culture

1972 • 277 citations

Ferritin-Conjugated Plant Agglutinins as Specific Saccharide Stains for Electron Microscopy: Application to Saccharides Bound to Cell Membranes

1971 • 275 citations

MEMBRANES OF ANIMAL CELLS

1968 • 275 citations

REGULATION OF INITIATION OF DNA SYNTHESIS IN CHINESE HAMSTER CELLS

1970 • 271 citations

Comparative Studies on the Carbohydrate-containing membrane components of normal and virus-transformed mouse fibroblasts. II. Separation of glycoproteins and glycopeptides by Sephadex chromatography

1969 • 259 citations

Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability.

1968 • 256 citations

Surface Glycoproteins of Normal and Transformed Cells: A Difference Determined by Sialic Acid and a Growth-Dependent Sialyl Transferase

1972 • 256 citations

REACTIONS OF NORMAL AND TUMOR CELL SURFACES TO ENZYMES, I. WHEAT-GERM LIPASE AND ASSOCIATED MUCOPOLYSACCHARIDES

1963 • 240 citations

TRANSFORMATION OF PROPERTIES OF AN ESTABLISHED CELL LINE BY SV40 AND POLYOMA VIRUS

1964 • 236 citations

pH as a Determinant of Cellular Growth and Contact Inhibition

1971 • 236 citations

Analysis of a functional change in membrane in the process of cell transformation by Rous sarcoma virus; alteration in the characteristics of sugar transport

1970 • 235 citations

TIME SEQUENCE OF NUCLEAR PORE FORMATION IN PHYTOHEMAGGLUTININ-STIMULATED LYMPHOCYTES AND IN H<scp>E</scp>L<scp>A</scp> CELLS DURING THE CELL CYCLE

1972 • 230 citations

Calcium as a Regulator of the Proliferation of Normal, but Not of Transformed, Chicken Fibroblasts in a Plasma-Containing Medium

1971 • 230 citations

Further Changes in Differentiation State Accompanying the Conversion of Chinese Hamster Cells to Fibroblastic Form by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate and Hormones

1971 • 227 citations

Lateral Diffusion of Phospholipids in a Vesicle Membrane

1971 • 219 citations

Binding of Radioactively Labelled Concanavalin A and Wheat Germ Agglutinin to Normal and Virus-transformed Cells

1971 • 214 citations

Reduced Adenyl Cyclase Activity in a Polyoma Virus Transformed Cell Line

1968 • 214 citations

Complementation and transformation by temperature-sensitive mutants of polyoma virus

1969 • 212 citations

Growth Inhibition of Polyoma-Transformed Cells by Contact with Static Normal Fibroblasts

1966 • 210 citations

The partial purification from calf serum of a fraction with multiplication‐stimulating activity for chicken fibroblasts in cell culture and with non‐suppressible insulin‐like activity

1972 • 209 citations

CELL-TRANSFORMING ABILITY OF A TEMPERATURE-SENSITIVE MUTANT OF POLYOMA VIRUS

1965 • 198 citations

Requirement of Serum for DNA Synthesis in BHK 21 Cells : Effects of Density, Suspension and Virus Transformation

1970 • 197 citations

CELL-CYCLE DEPENDENT DESQUAMATION OF HEPARAN SULFATE FROM THE CELL SURFACE

1972 • 197 citations

Cyclic Membrane Changes in Animal Cells: Transformed Cells Permanently Display a Surface Architecture Detected in Normal Cells Only during Mitosis

1971 • 193 citations

STUDIES ON CELL AGGREGATION: DEMONSTRATION OF MATERIALS WITH SELECTIVE CELL-BINDING ACTIVITY

1963 • 193 citations

Cell Density-Dependent Changes of Glycolipid Concentrations in Fibroblasts, and Loss of This Response in Virus-Transformed Cells

1970 • 190 citations

Reversible arrest of growth in G1 of an established fibroblast line (3T3)

1965 • 189 citations

A Side View of Moving Fibroblasts

1969 • 188 citations

Induction of cell division in medium lacking serum growth factor by SV40

1971 • 185 citations

Cell Aggregation: Role of Acid Mucopolysaccharides

1972 • 182 citations

Carbohydrate-containing membrane components of normal and virus-transformed mouse fibroblasts. I. Glucosamine-labeling patterns in 3T3, spontaneously transformed 3T3, and SV-40-transformed 3T3 cells

1969 • 180 citations

Glycopeptides from the Surface of Control and Virus-Transformed Cells

1971 • 179 citations

Intercellular Contact and Cell-Surface Galactosyl Transferase Activity

1972 • 178 citations

Studies on carcinogenesis by avian sarcoma viruses. VI. Differential multiplication of uninfected and of converted cells in response to insulin

1967 • 174 citations

Sialic acid transferases and sialic acid levels in normal and transformed cells

1970 • 174 citations

Enzymatic Basis for Platelet: Collagen Adhesion as the Primary Step in Haemostasis

1971 • 172 citations

CONTACT-INHIBITED REVERTANT CELL LINES ISOLATED FROM SV40-TRANSFORMED CELLS

1973 • 171 citations

Temperature-Dependent Alterations in Sugar Transport in Cells Infected by a Temperature-Sensitive Mutant of Rous Sarcoma Virus

1971 • 168 citations

Antigen Cap Formation in Cultured Fibroblasts: A Reflection of Membrane Fluidity and of Cell Motility

1972 • 167 citations

Binding of [3H]Concanavalin A to Normal and Transformed Cells

1973 • 165 citations

Regulation of growth and orientation in hamster cells transformed by polyoma virus

1964 • 164 citations

AN ASSAY FOR INTERCELLULAR ADHESIVE SPECIFICITY

1971 • 158 citations

PRODUCTION AND CHARACTERIZATION OF MULTIPLE-LAYERED POPULATIONS OF ANIMAL CELLS

1965 • 154 citations

FORMATION AND DISTRIBUTION OF NUCLEAR PORE COMPLEXES IN INTERPHASE

1971 • 153 citations

Serum Factor Requirements of Normal and Simian Virus 40-Transformed 3T3 Mouse Fibroblasts

1971 • 151 citations

The role of cell‐cell contact in “contact” inhibition of cell division: A review and new evidence

1972 • 150 citations

GANGLIOSIDES IN DNA VIRUS-TRANSFORMED AND SPONTANEOUSLY TRANSFORMED TUMORIGENIC MOUSE CELL LINES

1969 • 150 citations

Stimulation of cell growth in vitro by serum with and without growth factor Relation to contact inhibition and viral transformation

1970 • 145 citations

Temperature-Dependent Surface Changes in Cells Infected or Transformed by a Thermosensitive Mutant of Polyoma Virus

1971 • 144 citations

Regulation of Adenosine 3′:5′-Cyclic Monophosphate Phosphodiesterase Activity in Fibroblasts by Intracellular Concentrations of Cyclic Adenosine Monophosphate

1972 • 141 citations

Regulation of the Synthesis and the Stability of Ribosomal RNA during Contact Inhibition of Growth

1971 • 140 citations

Early alterations in amino acid pools and protein synthesis of diploid fibroblasts stimulated to synthesize DNA by addition of serum

1969 • 140 citations

pH AND POPULATION DENSITY IN THE REGULATION OF ANIMAL CELL MULTIPLICATION

1971 • 136 citations

Surface Glycoproteins and Glycolipids of Chicken Embryo Cells transformed by a Temperature-sensitive Mutant of Rous Sarcoma Virus

1972 • 136 citations

The Synthesis of Acidic Nuclear Proteins in the Prereplicative Phase of the Isoproterenol-stimulated Salivary Gland

1970 • 135 citations

Control of the Reversion of Properties in Transformed Cells

1970 • 133 citations

Effect of growth on the glycoproteins from the surface of control and Rous sarcoma virus transformed hamster cells

1971 • 132 citations

Enzymatic Block in the Synthesis of Gangliosides in DNA Virus-Transformed Tumorigenic Mouse Cell Lines

1970 • 130 citations

Nutritional Effects on the Polyribosome Distribution and Rate of Protein Synthesis in Ehrlich Ascites Tumor Cells in Culture

1970 • 130 citations

Reversion of Properties in Cells transformed by Polyoma Virus

1968 • 128 citations

SURFACE-SPECIFIC CHARACTERISTICS OF A CONTACT-INHIBITED CELL LINE CONTAINING THE SV40 VIRAL GENOME

1969 • 128 citations

Adenyl Cyclase in Normal and Transformed Fibroblasts in Tissue Culture

1971 • 124 citations

Conditions Determining Initiation of DNA Synthesis in 3T3 Cells

1970 • 124 citations

Studies on reactivity of tumor and normal cells to a wheat germ agglutinin.

1965 • 122 citations

CONTACT-INHIBITED REVERTANT CELL LINES ISOLATED FROM SV40-TRANSFORMED CELLS

1971 • 120 citations

Uridine transport and RNA synthesis in growing and in density‐inhibited animal cells

1971 • 118 citations

Quantitative Binding of ¹²⁵ I-Concanavalin A to Normal and Transformed Cells

1971 • 118 citations

Agglutination of Cells transformed by Rous Sarcoma Virus by Wheat Germ Agglutinin and Concanavalin A

1972 • 118 citations

CONTACT-INHIBITED REVERTANT CELL LINES ISOLATED FROM SV40-TRANSFORMED CELLS

1971 • 118 citations

Ultrastructural modifications of the cell surface and intercellular contacts of some transformed cell strains.

1969 • 118 citations

Migration of Mouse 3T3 Fibroblasts in Response to a Serum Factor

1971 • 117 citations

THE RELATIONSHIP OF CONCANAVALIN A BINDING TO LECTIN-INITIATED CELL AGGLUTINATION

1973 • 116 citations

Glycolipid Synthesis in Normal and Virus-Transformed Hamster Cell Lines

1972 • 115 citations

Contact-Inhibited Revertant Cell Lines Isolated from Simian Virus 40-Transformed Cells III. Concanavalin A-Selected Revertant Cells

1972 • 113 citations

Gene Activation in WI-38 Fibroblasts Stimulated to Proliferate

1972 • 112 citations

Platelet collagen adhesion characterization of collagen glucosyltransferase of plasma membranes of human blood platelets

1971 • 108 citations

Platelet adhesiveness and aggregation: The collagen:Glycosyl, polypeptide:N-acetylgalactosaminyl and glycoprotein:Galactosyl transferases of human platelets

1971 • 107 citations

Inhibition of DNA Synthesis in Animal Cells by Ethylene Diamine Tetraacetate, and Its Reversal by Zinc

1972 • 105 citations

Transfer of growth inhibition between normal and virus-transformed cells: autoradiographic studies using marked cells

1967 • 104 citations

Composition and Synthesis of Gangliosides in Rat Hepatocyte and Hepatoma Cell Lines

1969 • 103 citations

Reversion of Virus-transformed Cell Lines: Hyperploidy accompanies Retention of Viral Genes

1970 • 100 citations

Contact regulation of cell division in an epithelial‐like cell line

1968 • 99 citations

Levels of Cyclic AMP in Sparse and Dense Cultures of Growing and Quiescent 3T3 Cells

1972 • 96 citations

Mutation Causing Temperature-Sensitive Expression of Cell Transformation by a Tumor Virus

1972 • 96 citations

Glycosyltransferase Activities in Normal and Polyoma-transformed BHK Cells

1971 • 93 citations

Nucleotide pool levels in growing, inhibited, and transformed chick fibroblast cells

1970 • 91 citations

Induction of cell division: Role of cell membrane sites

1972 • 90 citations

Stimulation of DNA synthesis by isoproterenol and its inhibition by actinomycin D

1967 • 90 citations

Neoplastic Transformation In Vitro of a Clone of Adult Liver Epithelial Cells into Differentiated Hepatoma-Like Cells Under Conditions of Nutritional Stress

1972 • 86 citations

Advances in Calcitonin Research

1971 • 83 citations

Macromolecular glucosamine-containing component of the surface of cultivated mouse cells

1970 • 80 citations

Production of Mucopolysaccharides by Normal and Transformed Cells

1973 • 79 citations

A DIFFUSIBLE FACTOR WHICH SUSTAINS CONTACT INHIBITION OF REPLICATION

1969 • 76 citations

Control of Glycolipid Synthesis in a Cultured Hamster Cell Line

1971 • 75 citations

Birefringent Filamentous Organelle in BHK-21 Cells and Its Possible Role in Cell Spreading and Motility

1970 • 73 citations

Potassium: Effect on DNA Synthesis and Multiplication of Baby-Hamster Kidney Cells

1972 • 71 citations

Contact Inhibition of Transformed Cells Incompletely Restored by Dibutyryl Cyclic AMP

1972 • 69 citations

LOW-RESISTANCE JUNCTIONS BETWEEN CANCER CELLS IN VARIOUS SOLID TUMORS

1970 • 68 citations

A common biochemical change in SV40 and polyoma virus transformed mouse cells coupled to control of cell growth in culture

1971 • 68 citations

LOCAL STIMULATION OF GROWTH IN PRIMARY CULTURES OF CHICK EMBRYO FIBROBLASTS

1969 • 64 citations

Differences in the Binding of Fluorescent Concanavalin A to the Surface Membrane of Normal and Transformed Cells

1972 • 59 citations

The need for direct cell contact in “contact” inhibition of cell division in culture

1968 • 57 citations

Growth Inhibitor of Hamster Fibroblast Cells

1966 • 57 citations

The quantitative utilization of amino acids and glucose and contact inhibition of growth in cultures of the human diploid cell, WI-38

1970 • 57 citations

Induction of 3T3 cell division at the monolayer stage

1973 • 56 citations

Variable Behaviour of Blood Group H on HeLa Cell Populations synchronized with Thymidine

1968 • 55 citations

Surface alterations in transformed epithelial and fibroblastic cells in culture: A disturbance of membrane degradation versus biosynthesis?

1973 • 54 citations

DIBUTYRYL CYCLIC ADENOSINE 3' 5' MONOPHOSPHATE, SUGAR TRANSPORT, AND REGULATORY CONTROL OF CELL DIVISION IN NORMAL AND TRANSFORMED CELLS

1973 • 53 citations

CELL CYCLE-DEPENDENT CHANGES IN THE SURFACE MEMBRANE AS DETECTED WITH [3H]CONCANAVALIN A

1973 • 53 citations

Characterization of membrane-bound collagen galactosyltransferase of human blood platelets

1971 • 52 citations

Flattening, movement and control of division of epithelial-like cells

1970 • 51 citations

Changes in the carbohydrate content of the KB cell during the growth cycle

1971 • 49 citations

COMPARATIVE STUDIES IN ROUS SARCOMA WITH VIRUS, TUMOR CELLS, AND CHICK EMBRYO CELLS TRANSFORMED IN VITRO BY VIRUS

1961 • 48 citations

INHIBITION OF DNA SYNTHESIS IN CHICK EMBRYO CULTURES BY DEPRIVATION OF EITHER SERUM OR ZINC

1973 • 48 citations

Relationship of contact inhibition to tumor transplantability, morphology, and growth rate.

1969 • 47 citations

Migration and proliferation of diploid human fibroblasts following “wounding” of confluent monolayers

1969 • 46 citations

Turnover of Molecules Which Maintain the Normal Surfaces of Contact-Inhibited Cells

1972 • 46 citations

Stimulation of DNA and Protein Synthesis in Fetal-Rat Liver Cells by Serum from Partially Hepatectomized Rats

1972 • 45 citations

Defective Formation of the Lamellar Cytoplasm by Neoplastic Fibroblasts

1972 • 42 citations

Reversible Transformation by Urea of Contact-Inhibited Fibroblasts

1972 • 41 citations

Interaction between normal and transformed bovine fibroblasts in culture: I. cells transformed by rous sarcoma virus

1967 • 40 citations

Surface Changes in Temperature-Sensitive Simian Virus 40-Transformed Cells

1973 • 38 citations

Serum-Stimulated Release of Cell Contacts and the Initiation of Growth in Contact-Inhibited Chick Fibroblasts

1971 • 37 citations

TRANSPORT INHIBITORS RELEASED BY 3T3 MOUSE CELLS AND THEIR RELATION TO GROWTH CONTROL

1971 • 31 citations

A working hypothesis explaining the maintenance of the transformed state by SV40 and polyoma

1972 • 31 citations

Expression of Adenylate Cyclase, Catecholamine Receptor, and Cyclic Adenosine Monophosphate-Dependent Protein Kinase in Synchronized Culture of Chang's Liver Cells

1972 • 29 citations

Retransformation of ts SV40 Transformants by Murine Sarcoma Virus at Non-permissive Temperature

1972 • 29 citations

The effect of medium changes on the growth and metabolism of the human diploid cell, W1-38

1971 • 29 citations

Selective growth of human neoplastic cells in medium lacking serum growth factor

1971 • 24 citations

Interaction between normal and transformed bovine fibroblasts in culture: II cells transformed by polyoma virus

1968 • 24 citations

Trace Element Geochemistry of Apollo 16 Soil 68501

1972 • 16 citations

Cancer Research

1972 • 14 citations

Some theoretical aspects of intercellular bridges as a potential mechanism of cancerous proliferation

1969 • 10 citations

FORMATION OF POLYRIBOSOMES DURING RECOVERY FROM CONTACT INHIBITION OF REPLICATION

1971 • 9 citations

Fulfilling Fulton

1971 • 2 citations