Intraclonal molecular heterogeneity suggests a hierarchy of pathogenetic events in Burkitt's lymphoma

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents.

1994 • 410 citations

p53 mutations are associated with histologic transformation of follicular lymphoma

1993 • 367 citations

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma.

1995 • 359 citations

Point mutations in the c–Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas

1993 • 283 citations

Patterns of chromosomal breakpoint locations in Burkitt's lymphoma: relevance to geography and Epstein-Barr virus association

1991 • 257 citations

Binding and Suppression of the Myc Transcriptional Activation Domain by p107

1994 • 242 citations

Epstein-Barr virus infection precedes clonal expansion in Burkitt's and acquired immunodeficiency syndrome-associated lymphoma [see comments]

1991 • 205 citations

Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection.

1992 • 167 citations

Epstein-Barr virus in benign lymph node biopsies from individuals infected with the human immunodeficiency virus is associated with concurrent or subsequent development of non-Hodgkin's lymphoma

1991 • 159 citations

Epstein-Barr virus and Burkitt's lymphoma.

1992 • 118 citations

The pattern of p53 mutations in Burkitt's lymphoma differs from that of solid tumors.

1992 • 113 citations

Frequent mutation of the 5' noncoding region of the BCL-6 gene in acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas.

1997 • 110 citations

The Non-Hodgkin's Lymphomas

1997 • 77 citations

Role of the p53 tumor suppressor gene in the tumorigenicity of Burkitt's lymphoma cells.

1997 • 53 citations

Analysis of clonal rearrangements of the Ig heavy chain locus in acute leukemia

1996 • 45 citations

Cell populations during tumorigenesis in Eu-myc transgenic mice.

1993 • 22 citations

Cytogenetic Rearrangement of C-MYC Oncogene Occurs Prior to Infection with Epstein-Barr Virus in the Monoclonal Malignant B Cells From an AIDS Patient

1993 • 15 citations

PROGNOSTIC-SIGNIFICANCE OF P53 MUTATIONS IN SMALL NON-CLEAVED CELL LYMPHOMAS

1994 • 14 citations

Burkitt’s Lymphoma Cells Frequently Carry Monoallelic DJ Rearrangements

1992 • 6 citations