Peroxisome-Proliferator-Activated Receptor (PPAR)-γ Activation Stimulates Keratinocyte Differentiation

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

1999 • 2,880 citations

Nuclear Receptors and Lipid Physiology: Opening the X-Files

2001 • 2,040 citations

PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development

1999 • 1,904 citations

Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

1998 • 1,408 citations

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

2003 • 1,260 citations

Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression

1996 • 1,201 citations

PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

2001 • 1,062 citations

Epidermal differentiation: the bare essentials.

1990 • 651 citations

Growth, Adipose, Brain, and Skin Alterations Resulting from Targeted Disruption of the Mouse Peroxisome Proliferator-Activated Receptor β(δ)

2000 • 641 citations

Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta

1999 • 589 citations

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.

1989 • 569 citations

Orphan Nuclear Receptors: Shifting Endocrinology into Reverse

1999 • 498 citations

Peroxisome Proliferator-Activated Receptors: From Genes to Physiology

2001 • 425 citations

Critical roles of PPARβ/δ in keratinocyte response to inflammation

2001 • 408 citations

Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPARβ mutant mice

2001 • 407 citations

The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation

1997 • 370 citations

Antiapoptotic Role of PPARβ in Keratinocytes via Transcriptional Control of the Akt1 Signaling Pathway

2002 • 334 citations

Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis

2000 • 307 citations

Membrane Structures in Normal and Essential Fatty Acid-Deficient Stratum Corneum: Characterization by Ruthenium Tetroxide Staining and X-Ray Diffraction

1991 • 296 citations

Modulation of Keratinocyte Gene Expression and Differentiation by PPAR-Selective Ligands and Tetradecylthioacetic Acid

2001 • 241 citations

Peroxisome Proliferator-Activated Receptor (PPAR)-β/δ Stimulates Differentiation and Lipid Accumulation in Keratinocytes

2004 • 230 citations

Barrier function regulates epidermal lipid and DNA synthesis

1993 • 228 citations

Liver X Receptor Activators Display Anti-Inflammatory Activity in Irritant and Allergic Contact Dermatitis Models: Liver-X-Receptor-Specific Inhibition of Inflammation and Primary Cytokine Production

2003 • 224 citations

Troglitazone Improves Psoriasis and Normalizes Models of Proliferative Skin Disease

2000 • 206 citations

Keratinocyte Differentiation is Stimulated by Activators of the Nuclear Hormone Receptor PPARα

1998 • 175 citations

Topical Peroxisome Proliferator Activated Receptor-α Activators Reduce Inflammation in Irritant and Allergic Contact Dermatitis Models

2002 • 171 citations

Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier.

1997 • 161 citations

Stimulation of PPARα Promotes Epidermal Keratinocyte Differentiation In Vivo

2000 • 159 citations

Differential Expression of Peroxisome Proliferator-Activated Receptor Subtypes During the Differentiation of Human Keratinocytes

1998 • 159 citations

Peroxisome Proliferator-activated Receptor β Regulates Acyl-CoA Synthetase 2 in Reaggregated Rat Brain Cell Cultures

1999 • 132 citations

Peroxisome Proliferator-Activated Receptor-α Enhances Lipid Metabolism in a Skin Equivalent Model

2000 • 116 citations

Keratinocyte Differentiation in Hyperproliferative Epidermis: Topical Application of PPARα Activators Restores Tissue Homeostasis

2000 • 106 citations

Ligands and Activators of Nuclear Hormone Receptors Regulate Epidermal Differentiation During Fetal Rat Skin Development

1998 • 104 citations

Oxysterols Induce Differentiation in Human Keratinocytes and Increase Ap-1-Dependent Involucrin Transcription

2000 • 96 citations

Coordinate Regulation of Epidermal Differentiation and Barrier Homeostasis

2001 • 96 citations

Peroxisome proliferator-activated receptor gamma and the control of adipogenesis

1997 • 91 citations

Oxysterol Stimulation of Epidermal Differentiation is Mediated by Liver X Receptor-β in Murine Epidermis

2002 • 85 citations

Effect of Topical PPARβ/δ and PPARγ Agonists on Plaque Psoriasis

2003 • 58 citations