Antiapoptotic Role of PPARβ in Keratinocytes via Transcriptional Control of the Akt1 Signaling Pathway

How Matrix Metalloproteinases Regulate Cell Behavior

2001 • 3,860 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

1999 • 2,880 citations

NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

1999 • 2,147 citations

The protein kinase B/Akt signalling pathway in human malignancy

2002 • 1,609 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

TRANSFAC: an integrated system for gene expression regulation

2000 • 1,236 citations

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1997 • 1,050 citations

Akt1/PKBα Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice

2001 • 950 citations

Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene

2001 • 908 citations

NF-κB signaling pathways in mammalian and insect innate immunity

2001 • 892 citations

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

1998 • 654 citations

Growth, Adipose, Brain, and Skin Alterations Resulting from Targeted Disruption of the Mouse Peroxisome Proliferator-Activated Receptor β(δ)

2000 • 641 citations

Effects of peroxisome proliferator-activated receptor δ on placentation, adiposity, and colorectal cancer

2001 • 591 citations

Integrin-linked kinase (ILK) and its interactors

2001 • 441 citations

Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways

1998 • 421 citations

Critical roles of PPARβ/δ in keratinocyte response to inflammation

2001 • 408 citations

Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPARβ mutant mice

2001 • 407 citations

Peroxisome Proliferator-Activated Receptors

2003 • 373 citations

Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN

2001 • 358 citations

Genetic approaches in mice to understand Rel/NF-κB and IκB function: transgenics and knockouts

1999 • 322 citations

Anti-apoptotic Role of Focal Adhesion Kinase (FAK)

2000 • 291 citations

Positive regulation of the peroxisomal β‐oxidation pathway by fatty acids through activation of peroxisome proliferator‐activated receptors (PPAR)

1993 • 284 citations

Functional roles of Akt signaling in mouse skin tumorigenesis

2002 • 185 citations

Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation

2000 • 137 citations

A Tyrosine Kinase Signaling Pathway Accounts for the Majority of Phosphatidylinositol 3,4,5-Trisphosphate Formation in Chemoattractant-stimulated Human Neutrophils

1996 • 115 citations

Protein Kinase B and Rac Are Activated in Parallel within a Phosphatidylinositide 3OH-kinase-controlled Signaling Pathway

1998 • 88 citations

Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival

2000 • 87 citations

A Central Role of Bcl-XL in the Regulation of Keratinocyte Survival by Autocrine EGFR Ligands

1999 • 50 citations

Peroxisome proliferator-activated receptors: roles in tumorigenesis and chemoprevention in human cancer

2001 • 45 citations