BRAIN AMINO ACIDS

Tyrosine Hydroxylase

1964 • 2,038 citations

ISOLATION OF MELATONIN, THE PINEAL GLAND FACTOR THAT LIGHTENS MELANOCYTES¹

1958 • 1,634 citations

GABA in nervous system function

1977 • 1,087 citations

Brain Serotonin Content: Physiological Dependence on Plasma Tryptophan Levels

1971 • 1,006 citations

Aromatic l-Amino Acid Decarboxylase

1962 • 841 citations

Brain Serotonin Content: Increase Following Ingestion of Carbohydrate Diet

1971 • 721 citations

Applied Neurochemistry.

1969 • 587 citations

SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

1965 • 539 citations

Über Ausscheidung von Phenylbrenztraubensäure in den Harn als Stoffwechselanomalie in Verbindung mit Imbezillität.

1934 • 526 citations

Hydroxylation-Induced Migration: The NIH Shift

1967 • 519 citations

Homocystinuria: An Enzymatic Defect

1964 • 515 citations

Metabolic Abnormalities Detected in a Survey of Mentally Backward Individuals in Northern Ireland

1962 • 494 citations

B. TYROSINE HYDROXYLASE

1966 • 493 citations

3,4-Dihydroxyphenylethylamine β-Hydroxylase

1965 • 451 citations

Partial Purification and Characterization of Tryptophan Hydroxylase from Rabbit Hindbrain

1972 • 445 citations

The influence of chemical agents on the accumulation of adenosine 3',5'-Phosphate in slices of rabbit cerebellum.

1968 • 435 citations

Solubilization and Partial Purification of Tyrosine Hydroxylase from Bovine Adrenal Medulla

1971 • 412 citations

Purification and Properties of Hydroxyindole-O-methyl Transferase

1961 • 409 citations

A NEW SYNDROME: PROGRESSIVE FAMILIAL INFANTILE CEREBRAL DYSFUNCTION ASSOCIATED WITH AN UNUSUAL URINARY SUBSTANCE

1954 • 408 citations

Biochemical-physiology correlations in studies of the γ-aminobutyric acid system

1968 • 408 citations

Isolation of Melatonin and 5-Methoxyindole-3-acetic Acid from Bovine Pineal Glands

1960 • 408 citations

Transsulfuration in Mammals

1965 • 403 citations

HEREDITARY PELLAGRA-LIKE SKIN RASH WITH TEMPORARY CEREBELLAR ATAXIA, CONSTANT RENAL AMINO-ACIDURIA, AND OTHER BIZARRE BIOCHEMICAL FEATURES

1956 • 402 citations

ORGANIC-ACIDURIA, DECREASED RENAL AMMONIA PRODUCTION, HYDROPHTHALMOS, AND MENTAL RETARDATION<subtitle>A Clinical Entity</subtitle>

1952 • 397 citations

THE STRUCTURE OF THE PHENYLALANINE-HYDROXYLATION COFACTOR

1963 • 378 citations

The Distribution and Properties of a Histamine-methylating Enzyme

1959 • 371 citations

SPECIFICITY OF AMINO ACID ACYLASES

1952 • 349 citations

The pharmacology of amino acids related to gamma-aminobutyric acid.

1965 • 333 citations

Mechanism of inhibition of glutamine synthetase by methionine sulfoximine

1969 • 328 citations

Inhibitors of purified beef adrenal tyrosine hydroxylase

1965 • 327 citations

N-ACETYL-l-ASPARTIC ACID IN BRAIN

1956 • 325 citations

Purification and Characterization of Glutamate Decarboxylase from Mouse Brain

1973 • 318 citations

Phenylketonuria Due to a Deficiency of Dihydropteridine Reductase

1975 • 317 citations

AMINO ACID AND PROTEIN METABOLISM‐VI CEREBRAL COMPARTMENTS OF GLUTAMIC ACID METABOLISM

1961 • 295 citations

STUDIES ON THE DISTRIBUTION OF N-ACETYL-l-ASPARTIC ACID IN BRAIN

1957 • 292 citations

Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome

1969 • 287 citations

Release of gamma-aminobutyric acid from inhibitory nerves of lobster.

1966 • 284 citations

Mobilization and formation of histamine in the gastric mucosa as related to acid secretion

1964 • 284 citations

The identification of homocystine in the urine

1962 • 278 citations

Substrate specificity of steady-state amino acid transport in mouse brain slices

1965 • 263 citations

Biosynthesis of melatonin: enzymic conversion of serotonin to N-acetylserotonin

1960 • 256 citations

The Isolation and Characterization of Dihydropteridine Reductase from Sheep Liver

1972 • 256 citations

Amino Acid Transmitters

1970 • 235 citations

Serotonin as a mediator of reserpine action in brain.

1956 • 230 citations

Trans-sulfuration in Mammals

1967 • 223 citations

A DISEASE, PROBABLY HEREDITARY, CHARACTERISED BY SEVERE MENTAL DEFICIENCY AND A CONSTANT GROSS ABNORMALITY OF AMINOACID METABOLISM

1958 • 219 citations

Localized action of gamma‐aminobutyric acid on the crayfish muscle

1965 • 214 citations

Compartmentation of Amino Acid Metabolism

1969 • 209 citations

Phenylpyruvic oligophrenia deficiency of phenylalanine-oxidizing system.

1953 • 195 citations

Studies on Aromatic Amino Acid Uptake by Rat Brain in Vivo

1962 • 195 citations

Tryptophan Hydroxylation in Mammalian Systems

1968 • 194 citations

ATP, cyclic AMP, and magnesium increase the affinity of rat striatal tyrosine hydroxylase for its cofactor.

1975 • 184 citations

Uptake of Tyrosine by Rat Brain in Vivo

1960 • 182 citations

Subcellular distribution of taurine and cysteinesulphinate decarboxylase in developing rat brain

1971 • 179 citations

STUDIES ON PHENYLPYRUVIC OLIGOPHRENIA

1947 • 178 citations

Metabolism of norepinephrine in the central nervous system.

1966 • 178 citations

Increased Cystine in Leukocytes from Individuals Homozygous and Heterozygous for Cystinosis

1967 • 172 citations

HISTAMINE FORMATION IN RAT BRAIN IN VIVO: EFFECTS OF HISTIDINE LOADS¹²

1972 • 170 citations

UPTAKE AND RELEASE OF TAURINE FROM RAT BRAIN SLICES

1972 • 168 citations

The γ-Aminobutyric Acid-α-Ketoglutaric Acid Transaminase of Beef Brain

1958 • 168 citations

THE UPTAKE OF GLUTAMIC ACID AND GLUTAMINE BY BRAIN AND OTHER TISSUES OF THE RAT AND MOUSE

1950 • 167 citations

γ-AMINOBUTYRIC ACID-GLUTAMIC ACID TRANSAMINATION IN BRAIN

1953 • 166 citations

Heterogeneity of the mediated transport systems of amino acid uptake in brain

1966 • 166 citations

End-product inhibition of tyrosine hydroxylase as a possible mechanism for regulation of norepinephrine synthesis.

1967 • 163 citations

Purification and Some Physical Properties of Phenylalanine Hydroxylase from Rat Liver

1970 • 162 citations

PROPERTIES AND REGIONAL DISTRIBUTION OF HISTIDINE DECARBOXYLASE IN RAT BRAIN

1970 • 160 citations

ACETATE METABOLISM IN THE NERVOUS SYSTEM. N‐ACETYL‐<scp>l</scp>‐ASPARTIC ACID AND THE BIOSYNTHESIS OF BRAIN LIPIDS*

1966 • 159 citations

Inhibition of glutamine synthetase by methionine sulfoximine. Studies On Methionine sulfoximine phosphate

1969 • 158 citations

Amino Acid Transport

1972 • 157 citations

Phosphorylation of methionine sulfoximine by glutamine synthetase.

1968 • 156 citations

In vitro activation of rat liver phenylalanine hydroxylase by phosphorylation.

1976 • 149 citations

A Familial Disturbance of Histidine Metabolism

1961 • 148 citations

Inhibition of dopamine β-hydroxylase by fusaric acid (5-butylpicolinic acid) in vitro and in vivo

1970 • 145 citations

Rat Liver Phenylalanine Hydroxylase, an Iron Enzyme

1972 • 143 citations

The Stimulation of Rat Liver Phenylalanine Hydroxylase by Lysolecithin and α-Chymotrypsin

1973 • 143 citations

ORNITHINE DECARBOXYLASE ACTIVITY IN DEVELOPING RAT BRAIN

1972 • 141 citations

ACTIVE TRANSPORT OF AMINO ACID INTO CEREBRAL CORTEX SLICES*

1963 • 139 citations

The Phenylalanine Hydroxylating System from Mammalian Liver

1971 • 137 citations

DYNAMICS OF THE REGULATION OF HISTAMINE LEVELS IN MOUSE BRAIN¹

1972 • 134 citations

On the ultrastructural localization of noradrenaline in the central nervous system of the rat

1967 • 133 citations

Factor I and γ-Aminobutyric Acid

1956 • 132 citations

Brain Dysfunction in Metabolic Disorders

1975 • 132 citations

Control of cerebral metabolite levels

1968 • 131 citations

PURIFICATION STUDIES OF TYROSINE-α-KETOGLUTARIC ACID TRANSAMINASE

1956 • 131 citations

Tyrosinemia

1965 • 130 citations

Control of Pyrimidine Biosynthesis in Mammalian Tissues

1969 • 129 citations

THE BRAIN BARRIER SYSTEM‐II UPTAKE AND TRANSPORT OF AMINO ACIDS BY THE BRAIN*

1961 • 129 citations

The gamma-aminobutyric acid system in rabbit cerebellum.

1966 • 126 citations

Hyperpipecolatemia: A new metabolic disorder associated with neuropathy and hepatomegaly: A case study.

1968 • 122 citations

Pipecolic acid pathway: The major lysine metabolic route in the rat brain

1976 • 119 citations

Binding of γ-aminobutyric acid by mouse brain preparations

1963 • 119 citations

Kinetic studies of the enzymic dopamine β-hydroxylation reaction

1968 • 119 citations

Acetyl transport mechanisms. Involvement of N-Acetyl aspartic acid in de novo fatty acid biosynthesis in the developing rat brain

1968 • 119 citations

THE BLOCKING EFFECT OF y‐AMINOBUTYRIC ACID (GABA) AND THE ACTION OF RELATED COMPOUNDS ON SINGLE NERVE CELLS*

1959 • 118 citations

The Uptake of Tyrosine by Rat Brain in Vitro

1961 • 118 citations

Familial Hyperprolinemia

1965 • 116 citations

Control of cerebral metabolite levels

1967 • 116 citations

An anion stimulated l-glutamic acid decarboxylase in non-neural tissues

1970 • 114 citations

Neuropathological Findings in Phenyl-Pyruvic Oligophrenia (Phenyl-Ketonuria)

1950 • 113 citations

THE METABOLISM OF γ‐AMINOBUTYRIC ACID (GABA) IN THE LOBSTER NERVOUS SYSTEM—I

1967 • 112 citations

A CHEMICAL INVESTIGATION OF THE DEFECTS OF MYELINATION IN PHENYLKETONURIA

1962 • 111 citations

A carrier-mediated transfer model for the accumulation of 14C γ-aminobutyric acid by subcellular brain particles

1965 • 110 citations

Biochemical Studies of Synapses in Vitro

1969 • 110 citations

Initial Steps in Pyrimidine Synthesis in Ehrlich Ascites Carcinoma in Vitro

1967 • 110 citations

Oculo-Cerebro-Renal Syndrome

1968 • 109 citations

The enzymic acetylation of serotonin and other naturally ocurring amines

1961 • 109 citations

Inherited propionyl-CoA carboxylase deficiency in “ketotic hyperglycinemia”

1971 • 106 citations

CONCENTRATION OF HISTAMINE IN DIFFERENT PARTS OF BRAIN AND HYPOPHYSIS OF CAT AND ITS MODIFICATION BY DRUGS

1966 • 104 citations

Enzymes of arginine metabolism in brain

1960 • 103 citations

ARGININOSUCCINATE SYNTHETASE ACTIVITY AND CITRULLINE METABOLISM IN CELLS CULTURED FROM A CITRULLINEMIC SUBJECT

1967 • 102 citations

THE BRAIN BARRIER SYSTEM–III

1962 • 101 citations

HISTAMINE AND SOME ANTIHISTAMINES: THEIR ACTIONS ON CEREBRAL CORTICAL NEURONES

1968 • 100 citations

Characteristics of mammalian histidine decarboxylating enzymes

1961 • 99 citations

Hydroxylation of phenylalanine by purified preparations of adrenal and brain tyrosine hydroxylase

1965 • 98 citations

ARGININÆMIA WITH ARGINASE DEFICIENCY

1969 • 98 citations

COMPARTMENTATION OF GLUTAMIC ACID METABOLISM IN BRAIN SLICES*

1968 • 95 citations

Histidinemia

1962 • 94 citations

STUDIES ON THE CYCLOPHORASE SYSTEM

1949 • 94 citations

On the Nature of Enzymatic Defect in Phenylpyruvic Oligophrenia

1957 • 94 citations

Evidence for the lack of direct phosphorylation of bovine caudate tyrosine hydroxylase following activation by exposure to enzymatic phosphorylating conditions

1975 • 93 citations

ARGININOSUCCINIC ACIDURIA. ARGININOSUCCINASE AND ARGINASE IN HUMAN BLOOD CELLS.

1964 • 92 citations

The occurrence of N‐acetylaspartate amidohydrolase (Aminoacylase II) in the developing rat¹

1973 • 92 citations

The Nature of γ-Aminobutyric Acid

1970 • 87 citations

Studies on Conversion of Phenylalanine to Tyrosine in Phenylpyruvic Oligophrenia.

1957 • 85 citations

Histamine and Spermidine Content in Brain during Development

1969 • 84 citations

The Stimulation of Rat Liver Phenylalanine Hydroxylase by Phospholipids

1972 • 82 citations

Hartnup Disease

1965 • 80 citations

The Enzymatic Synthesis of N-Acetyl-L-aspartic Acid by Subcellular Preparations of Rat Brain

1969 • 80 citations

Studies on the glutamine and glutamic acid content of the rat brain during insulin hypoglycaemia

1950 • 80 citations

Effects of ouabain on cerebral metabolism and transport mechanisms in vitro

1962 • 79 citations

Association of the γ-aminobutyric acid system with a synaptic vesicle fraction from mouse brain

1968 • 78 citations

Lysine-ketoglutarate reductase in human tissues

1975 • 77 citations

Glutaric aciduria: Inherited deficiency of glutaryl-CoA dehydrogenase activity

1975 • 77 citations

The production of meta-chlorotyrosine from para-chlorophenylalanine by phenylalanine hydroxylase

1966 • 75 citations

Tryptophan-5-Hydroxylase in Mammalian Brain

1968 • 74 citations

Free Amino-Acids in Rat Brain During Insulin Shock

1951 • 73 citations

Alpha-ketoadipic aciduria, a new inborn error of lysine metabolism; biochemical studies

1975 • 72 citations

THE SUBCELLULAR DISTRIBUTION OF HISTAMINE, SLOW‐REACTING SUBSTANCE AND 5‐HYDROXYTRYPTAMINE IN THE BRAIN OF THE RAT

1963 • 72 citations

Detection of Hepatic Phenylalanine 4-Hydroxylase in Classical Phenylketonuria

1973 • 72 citations

Glutamate and Glutamine

1970 • 71 citations

The Biosynthesis of Serine in Mouse Brain Extracts

1965 • 71 citations

Purification and Characterization of Phenylalanine Hydroxylase-stimulating Protein from Rat Liver

1973 • 71 citations

�ber die Dopadecarboxylase und Histidindecarboxylase des Nervengewebes

1956 • 70 citations

THE BRAIN BARRIER SYSTEM—I THE EXCHANGE OF FREE AMINO ACIDS BETWEEN PLASMA AND BRAIN

1961 • 70 citations

Preparation and characterization of sheep brain glutamine synthetase

1969 • 69 citations

Nature of the Molecular Defect in Phenylketonuria and Hyperphenylalaninaemia

1972 • 67 citations

Substrate specificity of cerebral amino acid exit in vitro

1966 • 65 citations

Specificity of Cerebral Amino Acid Transport: A Kinetic Analysis

1968 • 65 citations

Biosynthesis of N-Acetyl-l-aspartic Acid

1959 • 65 citations

Lipid alterations in human brains in phenylketonuria

1967 • 65 citations

Perinatal changes in the free amino acid pool of the brain in mice

1973 • 64 citations

Initial Steps in Pyrimidine Synthesis in Ehrlich Ascites Carcinoma in Vitro

1965 • 64 citations

THE BRAIN BARRIER SYSTEM—V STEREOSPECIFICITY OF AMINO ACID UPTAKE, EXCHANGE AND EFFLUX

1963 • 64 citations

Compartmentation of Glutamic Acid Metabolism in Developing Cerebral Cortex

1965 • 64 citations

Sodium-dependent binding of γ-aminobutyric acid by morphologically characterized subcellular brain particles

1965 • 63 citations

Branched Chain α-Keto Acid Metabolism

1968 • 62 citations

Development of Myelin in Inherited Disorders of Amino Acid Metabolism

1968 • 62 citations

Hematoencephalic Exchange as a Function of Age

1957 • 62 citations

Isolation and characterization of a tyrosine hydroxylase cofactor from bovine adrenal medulla.

1971 • 62 citations

ADENOSYLMETHIONINE DECARBOXYLASE IN DEVELOPING RAT BRAIN

1973 • 61 citations

CLINICAL AND BIOCHEMICAL STUDIES ON TWO CASES OF HISTIDINEMIA.

1963 • 61 citations

Adaptive increase in mammalian histidine decarboxylase activity in response to nonspecific stress

1959 • 60 citations

TRANSAMINATION OF AROMATIC AMINO ACIDS IN RAT BRAIN

1964 • 60 citations

Junction potentials at adrenergic synapses.

1966 • 59 citations

The production of meta-tritiotyrosine from p-tritiophenylalanine by phenylalanine hydroxylase

1966 • 58 citations

DEVELOPMENTAL CHANGES IN Na⁺, K⁺AND ATP AND IN THE LEVELS AND TRANSPORT OF AMINO ACIDS IN INCUBATED SLICES OF RAT BRAIN

1971 • 56 citations

Characterization of succinate semialdehyde dehydrogenase from rat brain

1968 • 55 citations

THE MEASUREMENT OF FREE AND N‐ACETYLATED ASPARTIC ACIDS IN THE NERVOUS SYSTEM*

1966 • 55 citations

The uptake of amino acids by particulate fractions from brain

1969 • 54 citations

MAPLE SYRUP URINE DISEASE METABOLITES STUDIED IN CEREBELLUM CULTURES¹

1969 • 54 citations

CLINICAL AND BIOCHEMICAL STUDIES ON TWO CASES OF HISTIDINEMIA

1963 • 54 citations

CEREBRAL AMINO ACID TRANSPORT IN VITRO–III*

1965 • 54 citations

IN VIVO FORMATION AND CATABOLISM OF [¹⁴C]HISTAMINE IN MOUSE BRAIN

1970 • 54 citations

Retention of deuterium in p-tyrosine formed enzymatically from p-deuterophenylalanine

1966 • 53 citations

AMINO ACID TRANSPORT IN BRAIN CORTEX SLICES: III. THE UTILIZATION OF ENERGY FOR TRANSPORT

1962 • 53 citations

On the presence of different histidine decarboxylating enzymes in mammalian tissues

1961 • 52 citations

Succinic semialdehyde dehydrogenase: Purification and properties of the enzyme from monkey brain

1961 • 52 citations

L-Glutamic Acid Decarboxylase: A New Type in Glial Cells and Human Brain Gliomas

1970 • 50 citations

Occurrence of Gamma-Guanidinobutyric Acid

1957 • 50 citations

ACTIVATORS and INHIBITORS OF BRAIN GLUTAMINASE

1969 • 48 citations

Cerebral proteolipids in phenylketonuria

1968 • 48 citations

Kinetic properties of mammalian histidine decarboxylase

1967 • 48 citations

BRAIN CHOLESTEROL: BIOSYNTHESIS WITH SELECTED PRECURSORS IN VIVO

1961 • 47 citations

CEREBRAL AMINO ACID TRANSPORT IN VITRO—IV

1967 • 47 citations

Genetic Diseases of Metabolism

1972 • 46 citations

Relationship of ATP levels to amino acid transport in slices of mouse brain

1971 • 46 citations

Separation of enzyme activities catalysing spermidine and spermine synthesis in rat brain

1971 • 45 citations

BRAIN SUCCINATE SEMIALDEHYDE DEHYDROGENASE—I ASSAY AND DISTRIBUTION

1965 • 44 citations

IN VITRO RNA SYNTHESES BY INTACT RAT BRAIN NUCLEI¹

1968 • 44 citations

UREA SYNTHESIS IN BRAIN

1966 • 44 citations

Cerebral amino acid transport in vitro during development: A kinetic analysis

1970 • 43 citations

Sulfur Amino Acids

1970 • 43 citations

Production of m-methyltyrosine and p-hydroxymethylphenylalanine from p-methylphenylalanine by phenylalanine hydroxylase

1968 • 42 citations

Characterization of histidine decarboxylase from rat peritoneal fluid mast cells

1959 • 42 citations

α-Ketoadipic Aciduria: A Description of a New Metabolic Error in Lysine-Tryptophan Degradation

1975 • 41 citations

Citrullinemia with defective urea production.

1967 • 41 citations

Studies on the Biosynthesis of Carnitine

1965 • 41 citations

Separation and purification of aromatic amino acid transaminases from rat brain

1965 • 41 citations

Incorporation of 14C from glucose into α-keto acids and amino acids in rat brain and liver in vivo

1966 • 40 citations

ELECTROPHORESIS OF GLUTAMIC ACID DECARBOXYLASE (EC 4.1.1.15) FROM MOUSE BRAIN IN SODIUM DODECYL SULPHATE POLYACRYLAMIDE GELS¹

1973 • 40 citations

Biosynthesis and disposition of γ-guanidinobutyric acid in mammalian tissues

1963 • 40 citations

CITRULLINEMIA WITH DEFECTIVE UREA PRODUCTION

1967 • 40 citations

Occurence of a new L-glutamic acid decarboxylase in several blood vessels of the rabbit

1970 • 39 citations

A METHOD FOR STUDYING METABOLIC PATHWAYS IN THE BRAIN OF THE INTACT ANIMAL

1959 • 39 citations

Properties of a Carrier System to transport L–Dopa into Brain Slices

1963 • 38 citations

Studies on the distribution of free carnitine and the occurrence and nature of bound carnitine

1962 • 38 citations

Glycine: 2-oxoglutarate transaminase in rat cerebral cortex

1969 • 37 citations

REGIONAL DEVELOPMENT OF GLUTAMIC ACID COMPARTMENTATION IN IMMATURE BRAIN*

1966 • 37 citations

Inhibition of glutamine synthetase by methionine sulfone

1973 • 37 citations

SOME PHYSICAL PROPERTIES OF BOVINE ADRENAL MEDULLARY DOPAMINE β‐HYDROXYLASE

1973 • 37 citations

Lipid changes in the brain in phenylketonuria.

1968 • 36 citations

Energy dependence of amino acid uptake in brain slices

1969 • 36 citations

Enzyme Studies in a Patient with Saccharopinuria: A Defect of Lysine Metabolism

1974 • 35 citations

FURTHER STUDIES ON THE BINDING OF γ-AMINOBUTYRIC ACID BY BRAIN

1967 • 34 citations

ARGININOSUCCINIC ACIDURIA.

1969 • 33 citations

Isotope studies on the mechanism of action of adrenal tyrosine hydroxylase

1968 • 32 citations

On the hydroxylation of γ-butyrobetaine to carnitine invitro

1962 • 31 citations

The biosynthesis of phosphorylated tyrosine hydroxylase by organ cultures of rat adrenal medulla and superior cervical ganglia

1977 • 31 citations

FORMATION OF PUTREANINE, N‐(4‐AMINOBUTYL)‐3‐AMINOPROPIONIC ACID FROM SPERMIDINE IN RAT BRAIN AND LIVER

1973 • 31 citations

Polyamines and amino acid incorporation in vitro into microsomes of rat cerebral cortex

1970 • 30 citations

Effect of elevated blood tyrosine on subsequent intellectual development of premature infants

1966 • 30 citations

Hepatic phenylalanine 4-monooxygenase is a phosphoprotein.

1976 • 30 citations

Alpha-ketoadipic aciduria: Degradation studies with fibroblasts

1975 • 30 citations

CEREBRAL LIPIDS IN PHENYLKETONURIA

1966 • 30 citations

Cerebral lipids in phenylketonuria.

1966 • 30 citations

Uptake and metabolism of exogenous γ-aminobutyric acid by subcellular particles in a sodium-containing medium

1965 • 29 citations

Purification and properties of l-lysine-α-ketoglutarate reductase from human placenta

1975 • 29 citations

Central Synaptic Effects of ω-Guanidino Acids and Amino Acid Derivatives

1958 • 29 citations

Effect of Ferrous Ion on Tyrosine Hydroxylase of Bovine Adrenal Medulla

1972 • 28 citations

Saccharopinuria

1972 • 27 citations

Determination of gamma‐aminobutyric acid in single nerve cells of cat central nervous system

1970 • 27 citations

CHARACTERIZATION OF A NEW PHENYLALANINE METABOLITE IN PHENYLKETONURIA

1967 • 26 citations

Serine hydroxymethyltransferase in the central nervous system: regional and subcellular distribution studies

1973 • 26 citations

α-Amino adipic aciduria in an oligophrenic child

1974 • 25 citations

Mammalian histidine decarboxylase: Interaction between apoenzyme and pyridoxal-5'-phosphate

1967 • 24 citations

Familial hyperprolinemia and mental retardation

1969 • 23 citations

THE METABOLISM OF γ‐AMINOBUTYRIC ACID (GABA) IN THE LOBSTER NERVOUS SYSTEM—II

1967 • 23 citations

OXIDATION OF LEUCINE, ISOLEUCINE AND RELATED KETOACIDS IN DEVELOPING RABBIT BRAIN

1965 • 23 citations

Effect of spermidine on DNA‐dependent RNA polymerases from brain cell nuclei

1972 • 22 citations

Pyridoxal Phosphate: a Coenzyme for Histidine Decarboxylase

1959 • 21 citations

Histidine Decarboxylase and Dopa Decarboxylase

1970 • 20 citations

Synthesis of urea-cycle intermediates from citrulline in brain

1965 • 20 citations

Physiological release of histamine-14-C in the pyramidal cat

1967 • 19 citations

HYPERPROLINAEMIA TYPE 2

1968 • 18 citations

Gene therapy: a potentially invaluable aid to medicine and mankind.

1971 • 18 citations

New Metabolites of Phenylalanine

1964 • 17 citations

Metabolism of Catecholamines

1970 • 17 citations

DEFICIENT ARGININOSUCCINASE ACTIVITY IN BRAIN IN ARGININOSUCCINICACIDURIA

1968 • 15 citations

A Defect in Intestinal Amino Acid Transport in Lowe's Syndrome

1969 • 15 citations

Storage and Release of Monoamines in the Central Nervous System

1970 • 13 citations

An enzymatic basis for a blood-brain barrier? The gamma-glutamyl cycle-background and considerations relating to amino acid transport in the brain.

1974 • 11 citations

Occurrence of putreanine in human brain¹

1972 • 11 citations

The Urea Cycle

1971 • 11 citations

Brain Damage in the Aminoacidurias

1972 • 11 citations

Biochemistry of mental disease

1963 • 11 citations

The isolation of γ-butyrobetaine, crotonbetaine and carnitine from brains of animals killed during induced convulsions

1963 • 10 citations

The enzymic synthesis of γ-butyrobetaine and its CoA ester derivative

1962 • 10 citations

Excretion of Hypusine by Children and by Patients with Familial Hyperlysinemia

1973 • 9 citations

Biochemistry of Selected Amino Acids

1970 • 8 citations

Mescaline-induced changes of brain-cortex ribosomes. Role of spermidine in counteracting the destabilizing effect of mescaline on brain-cortex ribosomes

1971 • 8 citations

FATTY ACIDS OF THE BRAIN IN PHENYLKETONURIA*

1964 • 8 citations

EFFECTS OF GUANIDINOACETIC ACID, γ-GUANIDINOBUTYRIC ACID AND γ-GUANIDINOBUTYRYLMETHYLESTER ON THE MAMMALIAN CEREBRAL CORTEX

1961 • 7 citations

BRAIN γ-AMINOBUTYRIC-α-KETOGLUTARIC TRANSAMINASE

1959 • 7 citations

Mescaline-induced changes of brain-cortex ribosomes

1973 • 5 citations