The Nature of γ-Aminobutyric Acid

Thomas, Springfield, Illinois

1965 • 2,935 citations

Chromatographic and Electrophoretic Techniques

1961 • 1,691 citations

Organization of the primate retina: electron microscopy

1966 • 1,018 citations

METHODS IN MEDICAL RESEARCH

1967 • 890 citations

Regional Neurochemistry

1962 • 815 citations

γ-AMINOBUTYRIC ACID IN BRAIN: ITS FORMATION FROM GLUTAMIC ACID

1950 • 679 citations

The action of γ-Aminobutyric acid on cortical neurones

1967 • 612 citations

SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

1965 • 539 citations

THE FLUOROMETRIC MEASUREMENT OF PYRIDINE NUCLEOTIDES

1957 • 535 citations

STUDIES ON THE FREE AMINO ACIDS AND RELATED COMPOUNDS IN THE TISSUES OF THE CAT

1954 • 476 citations

The application of subcellular fractionation techniques to the study of brain function

1965 • 466 citations

Inhibition in the nervous system and gamma-aminobutyric acid

1961 • 412 citations

Biochemical-physiology correlations in studies of the γ-aminobutyric acid system

1968 • 408 citations

Fluorometric determination of aspartate, glutamate, and γ-aminobutyrate in nerve tissue using enzymic method

1966 • 388 citations

DISTRIBUTION OF SOME SYNAPTIC TRANSMITTER SUSPECTS IN CAT SPINAL CORD: GLUTAMIC ACID, ASPARTIC ACID, γ‐AMINOBUTYRIC ACID, GLYCINE, AND GLUTAMINE *

1967 • 373 citations

The Distribution of Glutamic Decarboxylase in the Nervous System of the Rhesus Monkey

1959 • 367 citations

FREE γ-AMINOBUTYRIC ACID IN BRAIN

1950 • 362 citations

Pharmacological properties of the postsynaptic inhibition by Purkinje cell axons and the action of ?-aminobutyric acid on Deiters neurones

1967 • 346 citations

Some properties of L-glutamic decarboxylase in mouse brain

1963 • 335 citations

The pharmacology of amino acids related to gamma-aminobutyric acid.

1965 • 333 citations

THE FLUORIMETRIC MEASUREMENT OF GLUTAMIC DECARBOXYLASE and ITS DISTRIBUTION IN BRAIN*

1958 • 330 citations

Progress in Brain Research

1968 • 324 citations

Physiological and chemical architecture of a lobster ganglion with particular reference to gamma-aminobutyrate and glutamate.

1967 • 296 citations

AMINO ACID AND PROTEIN METABOLISM‐VI CEREBRAL COMPARTMENTS OF GLUTAMIC ACID METABOLISM

1961 • 295 citations

Studies on the GABA pathway—I

1961 • 287 citations

Release of gamma-aminobutyric acid from inhibitory nerves of lobster.

1966 • 284 citations

Localization of origins of electroretinogram components by intraretinal recording in the intact cat eye

1961 • 280 citations

Protein Metabolism of The Nervous System

1964 • 275 citations

MECHANISM OF GAMMA AMINOBUTYRIC ACID (GABA) ACTION AND ITS RELATION TO SYNAPTIC INHIBITION

1958 • 275 citations

REGIONAL DISTRIBUTION OF γ‐AMINOBUTYRIC ACID (GABA) IN BRAIN OF THE RHESUS MONKEY*

1968 • 255 citations

Amino acid pools

1962 • 252 citations

Sodium 4-hydroxybutyrate

1964 • 251 citations

The distribution of glutamate decarboxylase and aspartate transaminase in subcellular fractions of rat and guinea-pig brain

1968 • 249 citations

Micro‐iontophoretic studies on neurones in the cuneate nucleus

1967 • 227 citations

Elevation of γ-Aminobutyric Acid in Brain: Selective Inhibition of γ-Aminobutyric-α-ketoglutaric Acid Transaminase

1961 • 224 citations

Localized action of gamma‐aminobutyric acid on the crayfish muscle

1965 • 214 citations

Convulsant hydrazides. I. In vitro and in vivo inhibition of vitamin B6 enzymes by convulsant hydrazides.

1957 • 213 citations

Soluble γ-Aminobutyric-Glutamic Transaminase from Pseudomonas fluorescens

1959 • 212 citations

CHANGES IN AMINO ACID CONCENTRATIONS ASSOCIATED WITH LOSS OF SPINAL INTERNEURONS *

1967 • 211 citations

Methods in Medical Research.

1960 • 207 citations

The Distribution of Glutamic-γ-Aminobutyric Transaminase in the Nervous System of the Rhesus Monkey

1959 • 192 citations

Gamma-Aminobutyric Acid

1959 • 192 citations

Is Glycine a Neurotransmitter ?: Inhibition of Motoneurones by Iontophoresis of Glycine

1967 • 189 citations

POSTNATAL CHANGES IN FREE AMINO ACID POOL OF RAT BRAIN

1966 • 176 citations

Ueber die Oxydation des Piperidins

1884 • 174 citations

FREE AMINO ACIDS AND RELATED COMPOUNDS IN DOG BRAIN: POST‐MORTEM AND ANOXIC CHANGES, EFFECTS OF AMMONIUM CHLORIDE INFUSION, AND LEVELS DURING SEIZURES INDUCED BY PICROTOXIN AND BY PENTYLENETETRAZOL*

1963 • 168 citations

The γ-Aminobutyric Acid-α-Ketoglutaric Acid Transaminase of Beef Brain

1958 • 168 citations

Heterogeneity of the mediated transport systems of amino acid uptake in brain

1966 • 166 citations

Elevation of γ-aminobutyric acid in brain with amino-oxyacetic acid and susceptibility to convulsive seizures in mice: A quantitative re-evaluation

1966 • 166 citations

γ-AMINOBUTYRIC ACID-GLUTAMIC ACID TRANSAMINATION IN BRAIN

1953 • 166 citations

ENTRY OF GLUCOSE CARBON INTO AMINO ACIDS OF RAT BRAIN AND LIVER IN VIVO AFTER INJECTION OF UNIFORMLY 14C-LABELLED GLUCOSE

1965 • 165 citations

GLUTAMIC ACID DECARBOXYLASE IN BRAIN

1951 • 161 citations

Amino Acids Released from the Cerebral Cortex in Relation to Its State of Activation

1965 • 158 citations

OCCLUSION AND METABOLISM OF γ‐AMINOBUTYRIC ACID BY BRAIN TISSUE*

1958 • 157 citations

Biochemical and Neurophysiological Development of the Brain in the Neonatal Period

1962 • 155 citations

The distribution of free amino acids in subcellular fractions of guinea-pig brain

1966 • 155 citations

IDENTIFICATION OF γ-AMINOBUTYRIC ACID IN BRAIN BY THE ISOTOPE DERIVATIVE METHOD

1950 • 154 citations

PHARMACOLOGICAL ASPECTS OF VITAMIN B6.

1964 • 152 citations

Thin-layer chromatography of 1-dimethylaminonaphthalene-5-sulphonyl derivatives of amino acids present in superfusates of cat cerebral cortex

1967 • 149 citations

DISPOSITION OF γ‐AMINOBUTYRIC ACID ADMINISTERED TO MAMMALS*

1958 • 148 citations

THE EXCITATION AND DEPRESSION OF MAMMALIAN CORTICAL NEURONES BY AMINO ACIDS

1964 • 143 citations

Gamma aminobutyric acid: circulatory and respiratory effects in different species; re‐investigation of the anti‐strychnine action in mice

1959 • 142 citations

ACTIVE TRANSPORT OF AMINO ACID INTO CEREBRAL CORTEX SLICES*

1963 • 139 citations

Pyridoxal Phosphokinases

1961 • 138 citations

THE α‐AMINOBUTYRIC ACID AND FACTOR I CONTENT OF BRAIN *

1963 • 131 citations

AMINO ACID METABOLISM IN RAT BRAIN STUDIED WITH ¹⁴C‐LABELLED GLUCOSE

1964 • 130 citations

On the permeability of the presynaptic terminal of the crayfish neuromuscular junction during synaptic inhibition and the action of γ‐aminobutyric acid

1966 • 129 citations

Some Metabolic Studies of -Aminobutyric Acid.

1958 • 129 citations

Energy-Linked Pyridine Nucleotide Reduction: Inhibitory Effects of Hyperbaric Oxygen In Vitro and In Vivo

1965 • 128 citations

THE METABOLISM OF GLUTAMATE IN HOMOGENATES AND SLICES OF BRAIN CORTEX

1963 • 127 citations

The gamma-aminobutyric acid system in rabbit cerebellum.

1966 • 126 citations

THE ROLE OF CARBON DIOXIDE IN THE NERVOUS SYSTEM

1960 • 126 citations

INTRACELLULAR LOCALIZATION OF GLUTAMATE DECARBOXYLASE, γ‐AMINOBUTYRATE TRANSAMINASE AND SOME OTHER ENZYMES IN BRAIN TISSUE

1965 • 123 citations

Protein Metabolism in the Nervous System

1961 • 119 citations

Binding of γ-aminobutyric acid by mouse brain preparations

1963 • 119 citations

THE BLOCKING EFFECT OF y‐AMINOBUTYRIC ACID (GABA) AND THE ACTION OF RELATED COMPOUNDS ON SINGLE NERVE CELLS*

1959 • 118 citations

DETERMINATION OF GLUTAMIC ACID, GLUTAMINE, GLUTATHIONE AND γ‐AMINOBUTYRIC ACID AND THEIR DISTRIBUTION IN BRAIN TISSUE

1958 • 117 citations

THE HISTOCHEMICAL DEMONSTRATION OF γ‐AMINOBUTYRIC ACID METABOLISM BY REDUCTION OF A TETRAZOLIUM SALT*

1965 • 116 citations

Metabolic and Neurophysiological Roles of γ-Aminobutyric Acid

1960 • 114 citations

THE METABOLISM OF γ‐AMINOBUTYRIC ACID (GABA) IN THE LOBSTER NERVOUS SYSTEM—I

1967 • 112 citations

A Simulation Study of the Metabolism and Compartmentation in Brain of Glutamate, Aspartate, the Krebs Cycle, and Related Metabolites

1966 • 111 citations

The Occurrence of γ-Aminobutyric Acid in Human Tissues Other than Brain

1966 • 110 citations

DISTRIBUTION OF γ‐AMINOBUTYRIC ACID IN THE LAYERS OF THE CEREBRAL AND CEREBELLAR CORTEX. IMPLICATIONS FOR ITS PHYSIOLOGICAL ROLE*

1962 • 110 citations

A carrier-mediated transfer model for the accumulation of 14C γ-aminobutyric acid by subcellular brain particles

1965 • 110 citations

γ-Hydroxybutyrate in Mammalian Brain

1964 • 109 citations

The distribution of homocarnosine in mammals

1962 • 108 citations

SUBCELLULAR DISTRIBUTION OF ENZYMES OF GLUTAMATE METABOLISM IN RAT BRAIN

1966 • 106 citations

On the relationship of brain gamma-aminobutyric acid to convulsions.

1962 • 103 citations

THE METABOLISM OF ?-AMINOBUTYRIC ACID (GABA) IN THE LOBSTER NERVOUS SYSTEM?GLUTAMIC DECARBOXYLASE

1968 • 102 citations

THE SUBCELLULAR DISTRIBUTIONS OF ACETYLCHOLINE, SUBSTANCE P, 5‐HYDROXYTRYPTAMINE, γ‐AMINOBUTYRIC ACID AND GLUTAMIC ACID IN BRAIN HOMOGENATES

1964 • 102 citations

THE METABOLISM OF AMINO ACIDS IN DEVELOPING RAT BRAIN*

1967 • 101 citations

Changes during growth in the volume and surface area of cortical neurons in the rabbit

1960 • 100 citations

Studies of sub-cellular distribution of γ-aminobutyric acid and glutamic decarboxylase in mouse brain

1963 • 99 citations

Purification and Some Properties of Mouse Brain L-Glutamic Decarboxylase^*

1966 • 99 citations

DISTRIBUTION OF SOME ENZYMES ASSOCIATED WITH THE METABOLISM OF GLUTAMATE, ASPARTATE, γ‐AMINOBUTYRATE AND GLUTAMINE IN CAT SPINAL CORD¹

1969 • 97 citations

Protein Synthesis Systems from Rat Brain^*

1966 • 95 citations

COMPARTMENTATION OF GLUTAMIC ACID METABOLISM IN BRAIN SLICES*

1968 • 95 citations

Differential Estimation of Gamma-butyrolactone and Gamma-hydroxybutyric Acid in Rat Blood and Brain

1964 • 95 citations

γ-butyrolactone and γ-hydroxybutyric acid—II. The pharmacologically active form

1966 • 92 citations

γ-Aminobutyric Acid (γABA), Vitamin B6, and Neuronal Function—A Speculative Synthesis

1964 • 91 citations

Inhibition of brain glutamic acid decarboxylase by phenylalanine, valine, and leucine derivatives: a suggestion concerning the etiology of the neurological defect in phenylketonuria and branched-chain ketonuria.

1961 • 90 citations

Synthesis of γ-aminobutyric acid from a pool of glutamic acid in brain after decapitation

1966 • 87 citations

γ-Aminobutyric Acid Content and Glutamic Decarboxylase and γ-Aminobutyrate Transaminase Activities in the Optic Lobe of the Developing Chick

1961 • 86 citations

Elevation of -Aminobutyric Acid in Rat Brain with Hydroxylamine.

1959 • 86 citations

PYRIDOXAL KINASE OF HUMAN BRAIN AND ITS INHIBITION BY HYDRAZINE DERIVATIVES

1959 • 85 citations

EFFECTS OF ENVIRONMENTAL COMPLEXITY ON CONSTITUENTS OF BRAIN AND LIVER*

1965 • 84 citations

γ-Guanidinobutyric Acid as a Convulsive Substance

1966 • 83 citations

Convulsant hydrazides. II. Comparison of electrical changes and enzyme inhibition induced by the administration of thiosemicarbazide.

1957 • 81 citations

The effect of aminooxyacetic acid on the metabolism of γ-aminobutyric acid in brain

1966 • 79 citations

γ-AMINOBUTYRIC ACID AND OTHER INHIBITORY SUBSTANCES

1965 • 78 citations

Subcellular distribution of glutamic decarboxylase and gamma- aminobutyric alpha-ketoglutaric transaminase

1963 • 78 citations

LEVELS AND INTRACELLULAR LOCALIZATION OF GLUTAMATE DECARBOXYLASE AND γ‐AMINOBUTYRATE TRANSAMINASE AND OTHER ENZYMES DURING THE DEVELOPMENT OF THE BRAIN*

1965 • 78 citations

Association of the γ-aminobutyric acid system with a synaptic vesicle fraction from mouse brain

1968 • 78 citations

A comparison of the enzymes and substrates of gamma-aminobutyric acid metabolism in lobster excitatory and inhibitory axons.

1965 • 76 citations

Carnitine precursors in the rat

1962 • 75 citations

CONTROL OF GLUTAMATE METABOLISM. THE EFFECT OF PYRUVATE

1965 • 74 citations

Metabolism of γ-hydroxybutyric acid

1964 • 72 citations

THE METABOLISM OF GAMMA AMINOBUTYRIC ACID IN THE LOBSTER NERVOUS SYSTEM

1970 • 72 citations

Métabolisme des dérivés guanidylés

1954 • 71 citations

Mode of action of gamma amino butyric acid on the cardiovascular system.

1963 • 71 citations

Distribution of γ‐aminobutyric acid and other amino acids in nervous tissue of various species

1958 • 70 citations

Toxic effects of oxygen at high pressure on the metabolism of <scp>d</scp>-glucose by dispersions of rat brain

1963 • 69 citations

The in vivo effects of hydrazines and vitamin B6 on the metabolism of gamma-aminobutyric acid.

1963 • 69 citations

Accurate freehand injection into the lateral brain ventricle of the conscious mouse.

1968 • 68 citations

Preliminary report on the metabolism of γ-butyrolactone and γ-hydroxybutyric acid

1965 • 67 citations

The inhibitory action of β‐hydroxy‐γ‐aminobutyric acid upon the seizure following stimulation of the motor cortex of the dog

1959 • 67 citations

-Aminobutyric Acid Content and Glutamic Decarboxylase Activity in Developing Mouse Brain

1951 • 67 citations

SOME NEUROCHEMICAL ASPECTS OF THE DEPRESSANT ACTION OF γ‐BUTYROLACTONE ON THE CENTRAL NERVOUS SYSTEM

1963 • 67 citations

The state of Factor I in rat brain: the effects of metabolic conditions and drugs

1960 • 64 citations

EXCHANGE TRANSAMINATION AND THE METABOLISM OF GLUTAMATE IN BRAIN

1965 • 63 citations

Sodium-dependent binding of γ-aminobutyric acid by morphologically characterized subcellular brain particles

1965 • 63 citations

Cerebellar Ataxia in Hamsters Inoculated with Rat Virus

1964 • 62 citations

Pharmacological studies of the optic system of the chick: Effect of γ-aminobutyric acid and pentobarbital

1964 • 61 citations

Demonstration of Thiosemicarbazide-Induced Convulsions in Rats with Elevated Brain Levels of -Aminobutyric Acid.

1960 • 60 citations

Glycine and spinal inhibition

1967 • 58 citations

A COMPARATIVE STUDY OF HYPERBARIC OXYGENINDUCED AND DRUG‐INDUCED CONVULSIONS WITH PARTICULAR REFERENCE TO γ‐AMINOBUTYRIC ACID METABOLISM*

1966 • 58 citations

A COMPARISON OF γ‐AMINOBUTYRIC ACID METABOLISM IN RABBIT AND MOUSE NERVOUS TISSUE*

1965 • 58 citations

The effects of hydrazines on rat brain 5-hydroxytryptamine, norepinephrine, and gamma-aminobutyric acid

1964 • 57 citations

THE ENZYMIC MEASUREMENT OF ? -AMINOBUTYRIC-? -OXOGLUTARIC TRANSAMINASE

1965 • 57 citations

THE INCORPORATION OF ¹⁴C DERIVED FROM GLUCOSE INTO THE PROTEINS OF THE BRAIN CORTEX, AT REST AND DURING ACTIVITY*

1960 • 56 citations

Characterization of succinate semialdehyde dehydrogenase from rat brain

1968 • 55 citations

Synaptic Effects of Systemic -Amino Butyric Acid in Cortical Regions of Increased Vascular Permeability

1958 • 55 citations

POSTNATAL CHANGES IN AMINO ACID CONTENT OF KITTEN CEREBRAL CORTEX*

1963 • 54 citations

Kinetics of Beef Heart Glutamic-Alanine Transaminase

1965 • 52 citations

Succinic semialdehyde dehydrogenase: Purification and properties of the enzyme from monkey brain

1961 • 52 citations

Purification and Some Properties of Mouse Brain γ-Aminobutyric-α-Ketoglutaric Acid Transaminase^*

1965 • 51 citations

Free amino acids and glutamate decarboxylase activity in brain of mice during drug-induced convulsions

1967 • 50 citations

Occurrence of Gamma-Guanidinobutyric Acid

1957 • 50 citations

Glucose Metabolism in Rat Brain In Vivo

1962 • 49 citations

Untersuchungen �ber die biochemischen Grundlagen der konvulsiven Wirkung von Hydraziden

1960 • 47 citations

INFLUENCE OF NEONATAL HYPOTHYROIDISM ON AMINO ACIDS IN DEVELOPING RAT BRAIN

1966 • 47 citations

The effect of central nervous system agents on rat-brain γ-aminobutyric acid level

1961 • 47 citations

Determination of Amino Acids from Plants by Paper Chromatography

1959 • 47 citations

STIMULATORY EFFECT OF γ‐AMINOBUTYRIC ACID UPON AMINO ACID INCORPORATION INTO PROTEIN BY A RIBOSOMAL SYSTEM FROM IMMATURE RAT BRAIN¹

1969 • 47 citations

BRAIN SUCCINATE SEMIALDEHYDE DEHYDROGENASE—II. CHANGES IN THE DEVELOPING RAT BRAIN

1967 • 47 citations

Effect of K⁺‐stimulation on GABA metabolism in brain slices in vitro

1967 • 46 citations

HYDRAZINOPROPIONIC ACID: A NEW INHIBITOR OF AMINOBUTYRATE TRANSAMINASE AND GLUTAMATE DECARBOXYLASEI

1968 • 46 citations

THE EFFECT OF ETHANOL ON THE CONCENTRATION OF γ-AMINOBUTYRIC ACID IN THE RAT BRAIN

1967 • 46 citations

DISTRIBUTION OF GLUTAMIC ACID DECARBOXYLASE ACTIVITY IN HUMAN BRAIN*

1962 • 46 citations

A METHOD OF DETERMINATION OF HOMOCARNOSINE AND ITS DISTRIBUTION IN MAMMALIAN TISSUES

1967 • 45 citations

BRAIN SUCCINATE SEMIALDEHYDE DEHYDROGENASE—I ASSAY AND DISTRIBUTION

1965 • 44 citations

EFFECT OF DIETARY PROTEIN CONTENT ON VISUAL DISCRIMINATION LEARNING and BRAIN BIOCHEMISTRY IN THE ALBINO RAT

1965 • 43 citations

THE EFFECTS OF PYRIDOXINE ANTAGONISTS AND OTHER CONVULSIVE AGENTS ON AMINO ACID CONCENTRATIONS OF THE MOUSE BRAIN*

1961 • 43 citations

Postnatal changes in free amino acid pool of rabbit brain

1967 • 43 citations

Inhibition of norepinephrine synthesis in mouse brain by blockade of dopamine-β-oxidase

1962 • 42 citations

Excitation and depression of cortical neurones by brain fractions released from micropipettes.

1965 • 42 citations

ON THE SITE OF ACTION OF γ-AMINOBUTYRIC ACID ON BLOOD PRESSURE

1958 • 42 citations

Gamma Hydroxybutyrate and Gamma Butyrolactone: Concentration in Rat Tissues during Anesthesia

1964 • 42 citations

The effect of gamma-amino-n-butyric acid and some related compounds on the cardiovascular system of anesthetized dogs.

1960 • 42 citations

THE ISOLATION OF HOMOANSERINE FROM BOVINE BRAIN^?

1967 • 42 citations

The action of inhibitory drugs on nerve terminals in crayfish muscle

1965 • 41 citations

THE EFFECT OF PERIODIC CONVULSIONS INDUCED BY 1,1‐DIMETHYLHYDRAZINE ON THE SYNTHESIS OF RAT BRAIN METABOLITES FROM [2‐¹⁴C]GLUCOSE

1966 • 41 citations

Studies on the Biosynthesis of Carnitine

1965 • 41 citations

Biosynthesis and disposition of γ-guanidinobutyric acid in mammalian tissues

1963 • 40 citations

Incorporation of 14C from glucose into α-keto acids and amino acids in rat brain and liver in vivo

1966 • 40 citations

The non‐selective blocking action of γ‐aminobutyric acid on the sensory cerebral cortex of the rat

1962 • 39 citations

Uptake of L‐histidine, L‐proline, L‐tyrosine and L‐ornithine by brain, intestinal mucosa, testis, kidney, spleen, liver, heart muscle, skeletal muscle and erythrocytes of the rat in vitro

1962 • 39 citations

Studies on the distribution of free carnitine and the occurrence and nature of bound carnitine

1962 • 38 citations

Modifications of brain glutamate decarboxylase activity by pyridoxal phosphate-γ-glutamyl hydrazone

1967 • 38 citations

Gamma-aminobutyric acid: a substrate for oxidative metabolism of cerebral cortex

1958 • 37 citations

REGIONAL DEVELOPMENT OF GLUTAMIC ACID COMPARTMENTATION IN IMMATURE BRAIN*

1966 • 37 citations

Succinate: Protective Agent against Hyperbaric Oxygen Toxicity

1965 • 37 citations

DETERMINATION OF γ‐AMINOBUTYRIC ACID AND OTHER FREE AMINO ACIDS IN WHOLE BRAINS OF RATS POISONED WITH β,β′‐IMINODIPROPIONITRILE AND α,γ‐DIAMINOBUTYRIC ACID WITH, OR WITHOUT, ADMINISTRATION OF THYROXINE

1966 • 36 citations

COMPARISON OF VARIOUS METHODS FOR THE DETERMINATION OF γ‐AMINOBUTYRIC AClD AND OTHER AMINO ACIDS IN RAT BRAIN WITH REFERENCE TO ETHANOL INTOXICATION

1963 • 36 citations

The influence of potassium on respiration and glycolysis by brain slices

1962 • 36 citations

The Metabolism of γ-Aminobutyric Acid-4-C14 by Intact Rats

1959 • 36 citations

Gamma-Aminobutyrylcholine

1958 • 35 citations

IDENTIFICATION OF 1, 4‐METHYLHISTAMINE, 1, 3‐DIAMINOPROPANE AND 2, 4‐DIAMINOBUTYRIC ACID IN BOVINE BRAIN*^†

1967 • 35 citations

Neurochemical and behavioral effects of isolation-rearing in the dog

1967 • 35 citations

The effeect of ethanol on GABA content of rat brain

1962 • 35 citations

THE REGULATION OF γ‐AMINOBUTYRIC ACID METABOLISM IN CEREBRAL CORTEX MITOCHONDRIA

1961 • 34 citations

FURTHER STUDIES ON THE BINDING OF γ-AMINOBUTYRIC ACID BY BRAIN

1967 • 34 citations

IDENTIFICATION OF MULTIPLE FORMS OF AMINOBUTYRATE TRANSAMINASE IN MOUSE AND RAT BRAIN : SUBCELLULAR LOCALIZATION

1968 • 33 citations

Über die freien gehirnaminosAuren und das äthanolamin der normalen ratte, sowie über das verhalten dieser stoffe nach experimenteller insulinhypoglykämie

1961 • 33 citations

THE INFLUENCE OF POTASSIUM CYANIDE POISONING ON THE γ‐AMINOBUTYRIC ACID LEVEL IN RAT BRAIN

1962 • 33 citations

Comparative Inhibition of Pyridoxal Kinase and Glutamic Acid Decarboxylase by Carbonyl Reagents.

1960 • 32 citations

Ueber die Oxydation des Piperidins

1883 • 32 citations

OXYGEN POISONING IN VARIOUS MAMMALIAN SPECIES AND THE POSSIBLE ROLE OF GAMMA‐AMINOBUTYRIC ACID METABOLISM *

1967 • 32 citations

Métabolisme des dérivés guanidylés I. Dégradation de l'arginine chez les invertébrés marins

1953 • 31 citations

On the hydroxylation of γ-butyrobetaine to carnitine invitro

1962 • 31 citations

NEUROCHEMICAL STUDIES WITH <scp>l</scp>‐CYCLOSERINE, A CENTRAL DEPRESSANT AGENT

1963 • 31 citations

Reserpin und γ-Aminobuttersäuregehalt des Gehirns

1961 • 30 citations

Cycloserine inhibition of gamma-aminobutyric-alpha-ketoglutaric transaminase

1964 • 30 citations

Effects of gamma-aminobutyric acid (GABA) and sodiumL-glutamate (glutamate) on the visual system and EEG if chicks

1967 • 30 citations

GAMMA-AMINOBUTYRIC ACID LEVELS IN THE BRAIN OF RATS EXPOSED TO OXYGEN AT HIGH PRESSURES

1963 • 30 citations

A new test preparation for bio‐assay of Factor I and gamma‐aminobutyric acid

1961 • 30 citations

Uptake and metabolism of exogenous γ-aminobutyric acid by subcellular particles in a sodium-containing medium

1965 • 29 citations

Central Synaptic Effects of ω-Guanidino Acids and Amino Acid Derivatives

1958 • 29 citations

METABOLIC AND PHARMACOLOGlCAL EFFECTS OF INJECTED AMINO ACIDS AND AMMONIA ON CORTICAL EPILEPTOGENIC LESIONS*

1961 • 29 citations

AMINO ACID CONTENT OF MONKEY BRAIN‐I

1962 • 29 citations

A GABA-related hypothesis on the mechanism of action of the antimotion sickness drugs.

1967 • 29 citations

FREE AMINO ACIDS IN BRAIN AND LIVER OF DEOXYPYRIDOXINE‐TREATED MICE SUBJECTED TO INSULIN SHOCK*

1962 • 28 citations

Nachweis von 4-Amino-n-butyrylcholin im Warmbl�tergehirn

1959 • 28 citations

BOUND γ-AMINOBUTYRIC AND OTHER AMINO ACIDS IN BRAIN

1965 • 28 citations

REACTIONS OF THE RESPIRATORY CHAIN IN BRAIN MITOCHONDRIAL PREPARATIONS

1962 • 28 citations

In vivo Conversion of γ-Hydroxybutyrate into γ-Aminobutyrate

1966 • 27 citations

Increase in the γ-Aminobutyric Acid Content of Rat Brain After Ingestion of Ethanol

1959 • 27 citations

SOME FREE AMINO ACIDS IN DOG BRAIN DURING DEVELOPMENT

1965 • 27 citations

AMINO ACID CONTENT OF MONKEY BRAIN—III

1964 • 27 citations

Liquid scintillation counting of C14-labeled amino acids on paper, using trinitrobenzene-1-sulfonic acid, and a modified combustion apparatus

1964 • 27 citations

Gamma-hydroxybutyric acid and sleep

1968 • 26 citations

Ion exchange chromatography of free amino acids in aqueous fluid and lens of the human eye.

1968 • 26 citations

Amino acid metabolism in various fractions of rat-brain homogenates with special reference to the effect of ethanol

1967 • 26 citations

The distribution of free amino acids in the central nervous system of garden dormice during hibernation

1966 • 25 citations

PENETRATION OF BLOOD‐BRAIN BARRIER BY γ‐AMINOBUTYRIC ACID AT SITES OF FREEZING

1967 • 25 citations

Convulsant effect of l-glutamic acid-γ-hydrazide by simultaneous treatment with pyridoxal phosphate

1964 • 24 citations

Characteristics of Blood-Brain Barrier to Gamma-Aminobutyric Acid in Neonatal Cat

1960 • 24 citations

VENTRICULO‐CISTERNAL PERFUSION OF AMINO ACIDS IN CAT BRAIN*—II

1966 • 24 citations

Pharmacological properties of γ-aminobutyrylcholine a supposed inhibitory neutrotransmitter

1960 • 24 citations

Succinic semialdehyde dehydrogenase from human brain

1964 • 24 citations

Formation of -Aminobutyric Acid (GABA) in Brain of Mice Treated with L-Glutamic Acid- -Hydrazide and Pyridoxal Phosphate- -Glutamyl Hydrazone.

1967 • 24 citations

The Protective Effect of Hyperbaric Oxygenation in Cerebral Anoxia

1966 • 23 citations

Studies on the mechanism of action of aminooxyacetic acid

1964 • 23 citations

THE METABOLISM OF γ‐AMINOBUTYRIC ACID (GABA) IN THE LOBSTER NERVOUS SYSTEM—II

1967 • 23 citations

Studies on the GABA pathway-II. The lack of effect of pyridoxal phosphate on GABA-KGA transaminase inhibition induced by amino-oxyacetic acid

1961 • 23 citations

Changes of Gamma-aminobutyric Acid, Glutamic Acid and Aspartic Acid in Various Brain Structures of Cats deprived of Paradoxical Sleep

1967 • 22 citations

Isolation and Probable Functions of Betaine Esters in Brain Metabolism

1960 • 22 citations

The γ-Aminobutyric Acid and Glutamic Acid Content of Brains of Rats treated with Toxopyrimidine

1959 • 22 citations

A neuropharmacological study of gamma-aminobutyryl-choline, gamma-aminobutyric acid, physostigmine and atropine.

1963 • 22 citations

SOME PROPERTIES OF RAT BRAIN MITOCHONDRIAL PREPARATIONS: RESPIRATORY CONTROL

1963 • 21 citations

Effects in vivo and in vitro of l-glutamic acid-γ-hydrazide on metabolism of some free amino acids in brain and liver

1966 • 21 citations

Acetylcholine-like activity in subcellular particles isolated from rat brain

1964 • 21 citations

Gamma aminobutyric acid and 5-hydroxytryptamine concentration in neurons and glial cells in the medical geniculate body of the cat

1963 • 21 citations

Anticonvulsive action of substances designed as inhibitors of γ-aminobutyric acid-α-ketoglutaric acid transaminase

1964 • 21 citations

Effects ofγ-amino-butyric acid on the potentials evoked in vitro in the superior colliculus

1967 • 21 citations

Glutamate decarboxylase and γ-Aminobutyrate transaminase in developing rat brain

1964 • 20 citations

Amino Acids in the Brain

1961 • 20 citations

BRAIN γ‐AMINOBUTYRATE‐α‐OXOGLUTARATE TRANSAMINASE—II. ACTIVITIES IN TWENTY‐FOUR REGIONS OF HUMAN BRAIN *

1967 • 20 citations

Studies on the mechanism of action of aminooxyacetic acid

1964 • 20 citations

The Neurochemistry of Nucleotides and Amino Acids.

1960 • 20 citations

BRAIN SUCCINATE SEMIALDEHYDE DEHYDROGENASE.—III. ACTIVITIES IN TWENTY‐FOUR REGIONS OF HUMAN BRAIN

1967 • 20 citations

The effect of iontophoretic injection of l-glutamic acid and γ-amino-N-butyric acid on the miniature end-plate potentials and contractures of the coxal muscles of the cockroach Periplaneta americana L.

1967 • 19 citations

Free β-Hydroxy-γ-amino-butyric Acid in Brain

1959 • 19 citations

DISTRIBUTION DES ACIDES AMINÉS LIBRES DANS LE SYSTÈME NERVEUX CENTRAL DU RAT AU COURS DU SOMMEIL ET DE L'ETAT DE VEILLE PROLONGÉE. THE DISTRIBUTION OF FREE AMINO ACIDS IN THE RAT BRAIN DURING SLEEP AND WAKEFULNESS

1965 • 19 citations

Postnatal changes in the concentration of nucleic acids, nucleotides and amino acids in the rat brain.

1966 • 19 citations

AMINO ACID TRANSPORT BY SLICES FROM VARIOUS REGIONS OF THE BRAIN

1966 • 19 citations

The determination of gamma-aminobutyric acid in brain

1962 • 19 citations

METABOLIC CONSEQUENCES OF LOCALIZED APPLICATION OF ELECTRICAL PULSES TO SECTIONS OF CEREBRAL WHITE MATTER

1960 • 19 citations

Synthesis of homocarnosine in muscle in vivo

1961 • 18 citations

The effect of various agents on the levels of homocarsonine in rat brain

1968 • 18 citations

Isolation and identification of homocarnosine from bovine brain

1965 • 18 citations

IN VITRO REVERSAL OF GLUTAMATE DECARBOXYLASE INHIBITION INDUCED BY 1,1‐DIMETHYLHYDRAZINE

1962 • 18 citations

THE SUBCELLULAR LOCALIZATION OF GLUTAMIC DECARBOXYLASE IN RAT BRAIN

1961 • 18 citations

Effect of γ-Aminobutyryl-Choline upon the Electrical Activity of the Cerebral Cortex

1958 • 18 citations

Horizontal cells of the retina as regulators of synaptic transmission

1967 • 18 citations

Critical period for detour learning in developing chicks

1966 • 17 citations

Effects of parenterally administered gamma-aminobutyric acid on the general behavior of the young chick

1965 • 17 citations

Action of penicillamine on mice, with special reference to its effect on glutamic acid decarboxylase in brain

1961 • 17 citations

Inhibition of pyridoxal phosphokinase by aminooxyacetic acid

1966 • 17 citations

Some correlations between picrotoxin-induced seizures and gamma-aminobutyric acid in animal brain.

1967 • 16 citations

The comparative production of γ-amino butyric acid in the maudsley reactive and non-reactive strains of rat

1967 • 15 citations

DELAY OR INHIBITION OF CONVULSIONS BY INTRAPERITONEAL INJECTIONS OF DIVERSE SUBSTANCES

1967 • 15 citations

On the glutamine and γ-aminobutyric acid contents of various regions of the cat brain

1962 • 15 citations

ON THE INTRACELLULAR LOCALIZATION OF GLUTAMATE DECARBOXYLASE AND γ‐AMINOBUTYRIC ACID IN MAMMALIAN BRAIN

1964 • 15 citations

The Neurochemistry of Nucleotides and Amino Acids

1961 • 15 citations

Metabolism of γ-Aminobutyric Acid in Brain Slices

1957 • 14 citations

Trennungsgang zur quantitativen bestimmung von keto- und aminosäuren in kleinen mengen des liquor cerebrospinalis

1962 • 14 citations

THE DISTRIBUTION OF γ‐AMINOBUTYRIC ACID IN THE MONKEY BRAIN DURING PICROTOXIN‐INDUCED SEIZURES*

1964 • 14 citations

DÉCARBOXYLASE GLUTAMIQUE ET HYDRAZONES DE PHOSPHO‐5‐PYRIDOXAL

1962 • 13 citations

THE RESPIRATORY CHAIN OF RAT CEREBRUM AND CEREBELLUM MITOCHONDRIA: RESPIRATION AND OXIDATIVE PHOSPHORYLATION

1964 • 13 citations

Exchange reactions catalyzed by γ-aminobutyric-glutamic transaminase

1960 • 13 citations

Sequential one-dimensional chromatography: Analysis of free amino acids in the brain

1960 • 13 citations

NEUROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES WITH THE ISONICOTINOYLHYDRAZONE OF PYRIDOXAL 5‐PHOSPHATE*

1964 • 13 citations

Cholinesterase and Glutamic Decarboxylase Levels in the Brain of the Hibernating Hamster

1963 • 13 citations

Changes of glutamine, glutamic acid and GABA in cortical and subcortical brain structures of hibernating and fully aroused ground squirrels (Citellus citellus)

1965 • 13 citations

Water and electrolytes in hydrated gray and white matter

1967 • 13 citations

Anticonvulsant properties of diacetylmonoxime (DAM)

1961 • 12 citations

Dünnschichtchromatographische Abtrennung von γ-aminobuttersäure aus hirnextrakten

1965 • 11 citations

Inhibition of Ascaris Muscle by γ-Aminobutyric Acid: a Possible New Assay Method

1966 • 11 citations

The isolation of γ-butyrobetaine, crotonbetaine and carnitine from brains of animals killed during induced convulsions

1963 • 10 citations

MOLECULAR STRUCTURE–ACTIVITY RELATIONSHIPS OF COMPOUNDS PROTECTING RATS AGAINST OXYGEN POISONING

1964 • 10 citations

THE ROLE OF γ‐AMINOBUTYRIC ACID IN THE METABOLISM OF GLUTAMIC ACID AND GLUTAMINE IN BRAIN

1963 • 10 citations

The enzymic synthesis of γ-butyrobetaine and its CoA ester derivative

1962 • 10 citations

THE γ‐AMINOBUTYRIC ACID CONTENT AND GLUTAMATE DECARBOXYLASE ACTIVITY OF BRAIN TUMOURS

1963 • 10 citations

Acetylcholine-like Activity of Acetyl-l-carnityl CoA in the Brains of Narcotized Rats

1966 • 9 citations

COMPARATIVE ASPECTS OF THE DISTRIBUTION OF NINHYDRIN-REACTIVE CONSTITUENTS IN NERVOUS TISSUE

1964 • 9 citations

EFFECTS OF SEVERAL EXCITANTS AND DEPRESSANTS ON GLUTAMIC ACID AND ITS METABOLITES CONCENTRATION IN RABBIT AND RAT BRAIN

1964 • 8 citations

Effect of Cations on γ-Aminobutyric Acid Level in Slices of Brain Cortex

1960 • 7 citations

EFFECTS OF GUANIDINOACETIC ACID, γ-GUANIDINOBUTYRIC ACID AND γ-GUANIDINOBUTYRYLMETHYLESTER ON THE MAMMALIAN CEREBRAL CORTEX

1961 • 7 citations

BRAIN γ-AMINOBUTYRIC-α-KETOGLUTARIC TRANSAMINASE

1959 • 7 citations

Aminooxyacetic Acid: Interactions with Gamma-Aminobutyric Acid and the Blood-Brain Barrier

1966 • 7 citations

Identification de la transaminase glutamique-γ-aminobutyrique dans le cerveau humain

1960 • 7 citations

INFLUENCES OF γ-AMINOBUTYRIC ACID AND SUBSTANCES POSSESSING SIMILAR CHEMICAL STRUCTURE ON HEXOKINASE OF THE BRAIN AND HEART MUSCLE

1958 • 7 citations

Effect of gamma-aminobutyric acid on pulmonary stretch receptors in the cat

1960 • 6 citations

Der Einbau von Glucose-Kohlenstoff in die freien Aminosäuren des Mäusegehirns unter dem Einfluß von Pyritinol

1967 • 6 citations

RELATIONSHIP BETWEEN THE HYPOTENSIVE ACTIVITY AND CHEMICAL STRUCTURE OF γ-AMINOBUTYRIC ACID IN THE RABBIT

1962 • 6 citations

Anti-convulsive Action of Gamma-Aminobutyryl Choline

1965 • 6 citations

Vorkommen und Bedeutung der γ-Aminobuttersäure im Zentralnervensystem

1961 • 5 citations

Chemical and enzymatic synthesis of γ-pantothenate

1964 • 4 citations

ACTION DE LA CYANACETYLHYDRAZONE DE PHOSPHO‐5′‐PYRIDOXAL SUR LA GLUTAMATE DECARBOXYLASE CEREBRALE. MODIFICATION DU TRACE ELECTROCORTICO‐GRAPHIQUE DU RAT. ACTION OF CYANACETYLHYDRAZONE OF PHOSPHO‐5′‐PYRIDOXAL ON THE CEREBRAL GLUTAMATE DECARBOXYLASE. MODIFICATION OF LECTROCORTICOGRAPHIC RECORD IN THE RAT

1966 • 4 citations

BRAIN γ-AMINOBUTYRIC ACID DURING AND ON SUPPRESSION OF THE RUNNING FIT

1960 • 4 citations

Über Peptidsynthesen, XLIV. Synthese von Ser4-Glu(NH2)8-Oxytocin (Glumitocin)

1968 • 4 citations

SOME NOTES ON THE COENZYME ACTIVITY OF PHOSPHOPYRIDOXAL DERIVATIVES FOR THE GLUTAMIC DECARBOXYLASE AND GLUTAMIC ASPARTIC TRANSAMINASE

1963 • 4 citations

INCORPORATION OF γ-AMINOBUTYRIC ACID (GABA) IN THE BRAIN AND INTERNAL ORGANS OF MICE

1961 • 4 citations

People and their Land

1967 • 3 citations

Studies on the glutamic acid decarboxylase activity of rat brain in the state of inhibition following electroshock.

1962 • 3 citations

Intracellular peptides of escherichia coli

1960 • 3 citations

TRANSAMINASE ACTIVITY OF NATURALLY OCCURRING INHIBITORY SUBSTANCES AND EFFECTS OF SOME DRUGS

1962 • 3 citations

TREATMENT OF EPILEPSY BY INTRASPINAL INJECTION OF γ‐AMINO‐β‐HYDROXYBUTYRIC ACID (GABOB)

1963 • 2 citations

[gamma-Aminobutyric acid-pyridoxine in the treatment of states of irritability and connected nervous disorders].

1962 • 2 citations

Bestimmung und Hydrolyse von 4-Amino-butyrylcholin

1960 • 2 citations

CHANGES IN GLUTAMIC ACID, GLUTAMINE, AND GAMMA-AMINOBUTYRIC ACID CONCENTRATIONS DURING POSTNATAL MATURATION OF THE CAT BRAIN.

1964 • 1 citations

NON-ENZYMIC TRANSAMINATION OF γ-AMINOBUTYRIC ACID

1963 • 1 citations

EFFECT OF ISONICOTINIC ACID HYDRAZIDE ON THE DECARBOXYLATION OF GLUTAMIC ACID IN BRAIN

1959 • 1 citations

AMINO ACIDS IN THE BRAIN —ANALYSIS OF AMINO ACIDS IN VARIOUS AREAS OF THE CEREBRAL CORTEX—

1963 • 1 citations

Effect of anoxia and acceleration on content of glutamic and gamma-aminobutyric acids in brain tissue.

1965 • 1 citations

[The specificity of the relations between gamma-aminobutyric acid and brain proteins].

1965 • 1 citations

The action of toxopyrimidine on glutamic decarboxylase and on some transaminase of rat tissues.

1959 • 1 citations

Regional changes in amino acid composition during anesthesia in the central nervous system of rats.

1966 • 1 citations