A Cdc2 dependent checkpoint maintains diploidy in Drosophila

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

1989 • 3,036 citations

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1989 • 1,237 citations

Drosophila: a laboratory manual

1990 • 1,081 citations

Expression of engrailed proteins in arthropods, annelids, and chordates

1989 • 1,019 citations

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2

1991 • 870 citations

Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryos.

1982 • 733 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Ordering S phase and M phase in the cell cycle

1994 • 596 citations

Genetic control of cell division patterns in the Drosophila embryo

1989 • 567 citations

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

1994 • 543 citations

Monoclonal antibodies against the Drosophila nervous system.

1982 • 534 citations

The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system

1991 • 504 citations

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

1991 • 502 citations

Three-dimensional architecture of a polytene nucleus

1983 • 453 citations

Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites.

1991 • 439 citations

The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string

1990 • 434 citations

The roles of Drosophila cyclins A and B in mitotic control

1990 • 429 citations

Expression and function of Drosophila cyclin a during embryonic cell cycle progression

1989 • 399 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

Drosophila: A laboratory manual

1990 • 350 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates.

1991 • 318 citations

Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis.

1994 • 301 citations

The regulation of the cell cycle during Drosophila embryogenesis: the transition to polyteny

1991 • 259 citations

Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis.

1995 • 220 citations

Drosophila cdc2 homologs: a functional homolog is coexpressed with a cognate variant.

1990 • 178 citations

Complementation of fission yeast cdc2ts and cdc25ts mutants identifies two cell cycle genes from Drosophila: a cdc2 homologue and string.

1990 • 139 citations

Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene.

1988 • 131 citations

The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes

1992 • 127 citations

Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.

1994 • 124 citations

Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a.

1991 • 121 citations

Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis

1989 • 120 citations

Genetic analysis of the Drosophila cdc2 homolog

1993 • 107 citations

Regulation and metamorphosis of the abdominal histoblasts ofDrosophila melanogaster

1979 • 102 citations

Control of imaginal cell development by the escargot gene of Drosophila

1993 • 100 citations

Control of imaginal cell development by the escargot gene of Drosophila

1993 • 83 citations

Embryonic origin of the imaginal discs of the head of Drosophila melanogaster

1993 • 66 citations

Qualifying for the license to replicate

1995 • 59 citations

A developmental and molecular analysis of Cdc2 mutations in Drosophila melanogaster

1993 • 17 citations