Purified plasma factor XIIa aggregates human neutrophils and causes degranulation

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

A biochemical abnormality in hereditary angioneurotic edema

1963 • 955 citations

Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site.

1979 • 602 citations

Human leukocyte granule elastase: rapid isolation and characterization

1976 • 550 citations

Neutrophil-mediated endothelial injury in vitro mechanisms of cell detachment.

1981 • 446 citations

Studies on the Pathogenesis of the Adult Respiratory Distress Syndrome

1982 • 359 citations

Mechanisms of Lysosomal Enzyme Release from Human Leukocytes: Microtubule Assembly and Membrane Fusion Induced by a Component of Complement

1973 • 329 citations

Experimental emphysema induced with purified human neutrophil elastase: tissue localization of the instilled protease.

1977 • 284 citations

Activation of plasma by contact with glass: evidence for a common reaction which releases plasma kinin and initiates coagulation

1958 • 255 citations

Activation of the classical pathway of complement by Hageman factor fragment.

1981 • 255 citations

A PREALBUMIN ACTIVATOR OF PREKALLIKREIN

1972 • 244 citations

Cytochalasin B: Effect on Lysosomal Enzyme Release from Human Leukocytes

1973 • 243 citations

Amino acid sequence of the heavy chain of human alpha-factor XIIa (activated Hageman factor).

1985 • 232 citations

Inhibition of activated Hageman factor and activated plasma thromboplastin antecedent by purified serum C1 inactivator.

1970 • 224 citations

Plasma Kallikrein and Hageman Factor in Gram-Negative Bacteremia

1970 • 221 citations

Human plasma kallikrein releases neutrophil elastase during blood coagulation.

1983 • 221 citations

Activation of plasminogen by human plasma kallikrein

1969 • 219 citations

Inhibition by CaINH of Hageman Factor Fragment Activation of Coagulation, Fibrinolysis, and Kinin Generation

1973 • 211 citations

The regulation of human factor XIIa by plasma proteinase inhibitors.

1985 • 205 citations

Leukocyte Elastase Release during Blood Coagulation

1982 • 204 citations

Degranulating stimuli increase the availability of receptors on human neutrophils for the chemoattractant f-met-leu-phe.

1980 • 161 citations

Stimulation of human neutrophil leukocyte aerobic glucose metabolism by purified chemotactic factors.

1974 • 158 citations

Structural Changes Accompanying Enzymatic Activation of Human Hageman Factor

1974 • 152 citations

MECHANISMS OF ACTIVATION OF C'1 ESTERASE IN HEREDITARY ANGIONEUROTIC EDEMA PLASMA IN VITRO

1968 • 142 citations

The activation of plasminogen by Hageman factor (Factor XII) and Hageman factor fragments.

1978 • 138 citations

Purified human plasma kallikrein aggregates human blood neutrophils.

1982 • 131 citations

Mechanisms of lysosomal enzyme release from human polymorphonuclear leukocytes. Effects of phorbol myristate acetate.

1975 • 123 citations

A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy.

1982 • 108 citations

Glucocorticoid and Mineralocorticoid Effects on Adrenocorticotropin and β-Endorphin in the Adrenalectomized Rat

1982 • 93 citations

Effects of neutrophil elastase and other proteases on porcine aortic endothelial prostaglandin I2 production, adenine nucleotide release, and responses to vasoactive agents.

1984 • 93 citations

Platelet-derived growth factor stimulates mouse 3T3 cell mitogenesis and leukocyte chemotaxis through different structural determinants.

1983 • 81 citations

A simplified procedure for the purification of C1̄‐inactivator from human plasma Interaction with complement subcomponents C1̄r and C1̄s

1977 • 78 citations

Plasma Kallikrein Activation and Inhibition during Typhoid Fever

1978 • 78 citations

An Improved Procedure for the Preparation of Crystalline Lactic Dehydrogenase from Hog Heart

1963 • 65 citations

Human Plasma Prekallikrein: a Rapid High-Yield Method for Purification

1979 • 65 citations

Effect of cleavage of the heavy chain of human plasma kallikrein on its functional properties

1985 • 58 citations

Differences in polymorphonuclear leukocyte aggregating responses among several species in response to chemotactic stimulation.

1980 • 43 citations

Studies on the Interaction between Collagen and a Plasma Kallikrein-Like Activity EVIDENCE FOR A SURFACE-ACTIVE ENZYME SYSTEM

1972 • 34 citations

Activation of hageman factor in the nephrotic syndrome

1974 • 29 citations

Deficiency of Hageman factor (factor XII) in patients with the nephrotic syndrome

1971 • 27 citations

The Skin Window as a Monitor of Leukocytic Functions in Contact Activation Factor Deficiencies in Man

1983 • 26 citations

Separation of large numbers of lymphocytes from human blood

1965 • 22 citations

Solid-phase immunoassay of dog neutrophil elastase

1980 • 19 citations

Preparation of β-XIIa (Hageman factor fragment) from human plasma

1982 • 16 citations

Plasma kallikrein and prorenin in patients with hereditary angioedema.

1985 • 12 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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